TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
ZNF790 | MAST | Esophagus | Healthy | C12orf66,CREB1,ORMDL1, etc. | 5.08e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Esophagus/Str/TF_Healthy/regulons_activity_in_dotplot.png) |
ZNF790 | PLA | Esophagus | Healthy | C12orf66,CREB1,ORMDL1, etc. | 4.71e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Esophagus/Str/TF_Healthy/regulons_activity_in_dotplot.png) |
ZNF790 | CD8TEREX | Liver | Cirrhotic | FAM49A,ICE2,ANKRD36B, etc. | 1.68e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Liver/Str/TF_Cirrhotic/regulons_activity_in_dotplot.png) |
ZNF790 | CD8TEREX | Liver | HCC | FAM49A,ICE2,ANKRD36B, etc. | 2.40e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Liver/Str/TF_HCC/regulons_activity_in_dotplot.png) |
ZNF790 | PLA | Prostate | Healthy | EGFL7,AARS,AASDH, etc. | 2.29e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Prostate/Str/TF_Healthy/regulons_activity_in_dotplot.png) |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF790 | SNV | Missense_Mutation | novel | c.1498N>A | p.His500Asn | p.H500N | Q6PG37 | protein_coding | deleterious(0) | probably_damaging(0.933) | TCGA-EO-A22X-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unspecific | Carboplatin | Complete Response |
ZNF790 | SNV | Missense_Mutation | novel | c.1141N>T | p.Leu381Phe | p.L381F | Q6PG37 | protein_coding | deleterious(0.01) | possibly_damaging(0.647) | TCGA-EO-A3B0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | novel | c.350N>C | p.Phe117Ser | p.F117S | Q6PG37 | protein_coding | tolerated(0.06) | benign(0.003) | TCGA-EO-A3B0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | novel | c.1747N>A | p.His583Asn | p.H583N | Q6PG37 | protein_coding | deleterious(0) | benign(0.233) | TCGA-EY-A1GD-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | | c.1427N>T | p.Arg476Ile | p.R476I | Q6PG37 | protein_coding | deleterious(0) | possibly_damaging(0.855) | TCGA-EY-A1GI-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | rs201218573 | c.158N>T | p.Ala53Val | p.A53V | Q6PG37 | protein_coding | tolerated(1) | benign(0) | TCGA-FI-A2D0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | novel | c.1051N>G | p.Ser351Ala | p.S351A | Q6PG37 | protein_coding | tolerated(0.19) | benign(0.285) | TCGA-FI-A2D5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatinum | PD |
ZNF790 | SNV | Missense_Mutation | novel | c.617N>A | p.Thr206Asn | p.T206N | Q6PG37 | protein_coding | tolerated(0.1) | benign(0.06) | TCGA-FI-A2D5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatinum | PD |
ZNF790 | SNV | Missense_Mutation | rs772363425 | c.239N>T | p.Ser80Leu | p.S80L | Q6PG37 | protein_coding | tolerated(0.06) | benign(0.139) | TCGA-FI-A2D5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatinum | PD |
ZNF790 | insertion | Frame_Shift_Ins | novel | c.282dupT | p.Glu95Ter | p.E95* | Q6PG37 | protein_coding | | | TCGA-B5-A3FC-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |