![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: ZFP82 |
Gene summary for ZFP82 |
![]() |
Gene information | Species | Human | Gene symbol | ZFP82 | Gene ID | 284406 |
Gene name | ZFP82 zinc finger protein | |
Gene Alias | ZNF545 | |
Cytomap | 19q13.12 | |
Gene Type | protein-coding | GO ID | GO:0006139 | UniProtAcc | D3Y299 |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
284406 | ZFP82 | HCC1 | Human | Liver | HCC | 4.32e-24 | 2.68e+00 | 0.5336 |
284406 | ZFP82 | HCC2 | Human | Liver | HCC | 1.42e-29 | 2.39e+00 | 0.5341 |
284406 | ZFP82 | HCC5 | Human | Liver | HCC | 9.75e-34 | 2.48e+00 | 0.4932 |
284406 | ZFP82 | male-WTA | Human | Thyroid | PTC | 2.03e-06 | 4.03e-02 | 0.1037 |
284406 | ZFP82 | PTC01 | Human | Thyroid | PTC | 8.76e-07 | 5.17e-02 | 0.1899 |
284406 | ZFP82 | PTC04 | Human | Thyroid | PTC | 1.63e-02 | 3.42e-02 | 0.1927 |
284406 | ZFP82 | PTC06 | Human | Thyroid | PTC | 4.31e-02 | 7.02e-02 | 0.2057 |
284406 | ZFP82 | PTC07 | Human | Thyroid | PTC | 1.31e-09 | 7.27e-02 | 0.2044 |
284406 | ZFP82 | ATC12 | Human | Thyroid | ATC | 1.87e-02 | 4.69e-02 | 0.34 |
284406 | ZFP82 | ATC13 | Human | Thyroid | ATC | 2.57e-33 | 5.60e-01 | 0.34 |
284406 | ZFP82 | ATC2 | Human | Thyroid | ATC | 3.00e-05 | 5.14e-01 | 0.34 |
284406 | ZFP82 | ATC4 | Human | Thyroid | ATC | 5.63e-03 | 5.60e-02 | 0.34 |
284406 | ZFP82 | ATC5 | Human | Thyroid | ATC | 1.11e-34 | 6.21e-01 | 0.34 |
Page: 1 |
![]() |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZFP82 | SNV | Missense_Mutation | rs749551905 | c.490N>A | p.His164Asn | p.H164N | Q8N141 | protein_coding | tolerated(0.07) | benign(0.03) | TCGA-DD-AAE4-01 | Liver | liver hepatocellular carcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
ZFP82 | SNV | Missense_Mutation | c.1152N>G | p.His384Gln | p.H384Q | Q8N141 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-ED-A4XI-01 | Liver | liver hepatocellular carcinoma | Male | <65 | I/II | Unknown | Unknown | SD | |
ZFP82 | SNV | Missense_Mutation | c.854A>C | p.Lys285Thr | p.K285T | Q8N141 | protein_coding | deleterious(0.04) | benign(0.015) | TCGA-G3-A3CK-01 | Liver | liver hepatocellular carcinoma | Male | <65 | I/II | Unknown | Unknown | SD | |
ZFP82 | SNV | Missense_Mutation | c.332N>T | p.Gly111Val | p.G111V | Q8N141 | protein_coding | deleterious(0.04) | possibly_damaging(0.71) | TCGA-44-8120-01 | Lung | lung adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD | |
ZFP82 | SNV | Missense_Mutation | c.635A>G | p.His212Arg | p.H212R | Q8N141 | protein_coding | deleterious(0.04) | possibly_damaging(0.608) | TCGA-49-6743-01 | Lung | lung adenocarcinoma | Female | >=65 | III/IV | Chemotherapy | cisplatin | SD | |
ZFP82 | SNV | Missense_Mutation | c.1334T>C | p.Ile445Thr | p.I445T | Q8N141 | protein_coding | tolerated(1) | benign(0.001) | TCGA-49-6761-01 | Lung | lung adenocarcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD | |
ZFP82 | SNV | Missense_Mutation | c.1027T>C | p.Cys343Arg | p.C343R | Q8N141 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-69-7763-01 | Lung | lung adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD | |
ZFP82 | SNV | Missense_Mutation | c.699A>T | p.Glu233Asp | p.E233D | Q8N141 | protein_coding | deleterious(0) | benign(0.314) | TCGA-69-7979-01 | Lung | lung adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD | |
ZFP82 | SNV | Missense_Mutation | c.581N>C | p.Gly194Ala | p.G194A | Q8N141 | protein_coding | tolerated(0.06) | probably_damaging(0.992) | TCGA-86-8358-01 | Lung | lung adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD | |
ZFP82 | SNV | Missense_Mutation | novel | c.548A>T | p.Gln183Leu | p.Q183L | Q8N141 | protein_coding | tolerated(0.11) | benign(0.334) | TCGA-NJ-A4YQ-01 | Lung | lung adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
Page: 1 2 3 4 5 6 7 8 9 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |