GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:001603210 | Cervix | CC | viral process | 109/2311 | 415/18723 | 5.40e-15 | 6.46e-12 | 109 |
GO:001905810 | Cervix | CC | viral life cycle | 87/2311 | 317/18723 | 2.20e-13 | 1.20e-10 | 87 |
GO:004440310 | Cervix | CC | biological process involved in symbiotic interaction | 71/2311 | 290/18723 | 7.94e-09 | 6.98e-07 | 71 |
GO:001907910 | Cervix | CC | viral genome replication | 35/2311 | 131/18723 | 6.11e-06 | 1.49e-04 | 35 |
GO:00457876 | Cervix | CC | positive regulation of cell cycle | 66/2311 | 313/18723 | 7.78e-06 | 1.81e-04 | 66 |
GO:00073466 | Cervix | CC | regulation of mitotic cell cycle | 88/2311 | 457/18723 | 1.26e-05 | 2.60e-04 | 88 |
GO:00346129 | Cervix | CC | response to tumor necrosis factor | 55/2311 | 253/18723 | 1.75e-05 | 3.32e-04 | 55 |
GO:002261310 | Cervix | CC | ribonucleoprotein complex biogenesis | 88/2311 | 463/18723 | 2.11e-05 | 3.82e-04 | 88 |
GO:002261810 | Cervix | CC | ribonucleoprotein complex assembly | 49/2311 | 220/18723 | 2.52e-05 | 4.29e-04 | 49 |
GO:007182610 | Cervix | CC | ribonucleoprotein complex subunit organization | 49/2311 | 227/18723 | 5.91e-05 | 8.54e-04 | 49 |
GO:000838010 | Cervix | CC | RNA splicing | 76/2311 | 434/18723 | 9.79e-04 | 8.19e-03 | 76 |
GO:00457862 | Cervix | CC | negative regulation of cell cycle | 67/2311 | 385/18723 | 2.21e-03 | 1.59e-02 | 67 |
GO:00459302 | Cervix | CC | negative regulation of mitotic cell cycle | 44/2311 | 235/18723 | 3.02e-03 | 1.99e-02 | 44 |
GO:000037710 | Cervix | CC | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 55/2311 | 320/18723 | 6.71e-03 | 3.70e-02 | 55 |
GO:000039810 | Cervix | CC | mRNA splicing, via spliceosome | 55/2311 | 320/18723 | 6.71e-03 | 3.70e-02 | 55 |
GO:000037510 | Cervix | CC | RNA splicing, via transesterification reactions | 55/2311 | 324/18723 | 8.61e-03 | 4.44e-02 | 55 |
GO:0018958 | Cervix | HSIL_HPV | phenol-containing compound metabolic process | 12/737 | 110/18723 | 1.31e-03 | 1.50e-02 | 12 |
GO:0016032 | Colorectum | AD | viral process | 168/3918 | 415/18723 | 4.67e-20 | 3.66e-17 | 168 |
GO:0008380 | Colorectum | AD | RNA splicing | 169/3918 | 434/18723 | 3.59e-18 | 2.04e-15 | 169 |
GO:0000377 | Colorectum | AD | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 130/3918 | 320/18723 | 5.88e-16 | 2.16e-13 | 130 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
HDC | SNV | Missense_Mutation | | c.1639N>C | p.Asp547His | p.D547H | P19113 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.648) | TCGA-22-1012-01 | Lung | lung squamous cell carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
HDC | SNV | Missense_Mutation | novel | c.827N>G | p.Tyr276Cys | p.Y276C | P19113 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-22-5479-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Chemotherapy | carboplatin | SD |
HDC | SNV | Missense_Mutation | novel | c.994C>A | p.Pro332Thr | p.P332T | P19113 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-22-A5C4-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
HDC | SNV | Missense_Mutation | | c.377N>G | p.Met126Arg | p.M126R | P19113 | protein_coding | deleterious(0) | probably_damaging(0.94) | TCGA-33-4583-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
HDC | SNV | Missense_Mutation | | c.1915G>T | p.Val639Phe | p.V639F | P19113 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.999) | TCGA-39-5027-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |
HDC | SNV | Missense_Mutation | novel | c.1685N>G | p.Lys562Arg | p.K562R | P19113 | protein_coding | tolerated_low_confidence(0.09) | benign(0.001) | TCGA-52-7810-01 | Lung | lung squamous cell carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
HDC | SNV | Missense_Mutation | novel | c.37N>C | p.Glu13Gln | p.E13Q | P19113 | protein_coding | tolerated(0.11) | benign(0.057) | TCGA-52-7810-01 | Lung | lung squamous cell carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
HDC | SNV | Missense_Mutation | | c.848N>A | p.Cys283Tyr | p.C283Y | P19113 | protein_coding | deleterious(0) | probably_damaging(0.994) | TCGA-60-2710-01 | Lung | lung squamous cell carcinoma | Female | >=65 | I/II | Chemotherapy | pemetrexed | SD |
HDC | SNV | Missense_Mutation | | c.1575G>C | p.Gln525His | p.Q525H | P19113 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.707) | TCGA-66-2742-01 | Lung | lung squamous cell carcinoma | Male | >=65 | III/IV | Unknown | Unknown | SD |
HDC | SNV | Missense_Mutation | novel | c.11N>T | p.Pro4Leu | p.P4L | P19113 | protein_coding | tolerated(0.42) | benign(0) | TCGA-68-7757-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |