TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
ZNF197 | CD4TN | Breast | ADJ | NLN,SLC27A3,CENPB, etc. | 3.25e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Breast/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF197 | M2MAC | Breast | Healthy | NLN,SLC27A3,CENPB, etc. | 7.59e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Breast/Str/TF_Healthy/regulons_activity_in_dotplot.png) |
ZNF197 | TFH | Breast | Precancer | NLN,SLC27A3,CENPB, etc. | 2.24e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Breast/Str/TF_Precancer/regulons_activity_in_dotplot.png) |
ZNF197 | ECM | Lung | AAH | TAFA2,AGK,ATP1A1-AS1, etc. | 3.84e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_AAH/regulons_activity_in_dotplot.png) |
ZNF197 | ECM | Lung | ADJ | TAFA2,AGK,ATP1A1-AS1, etc. | 3.51e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF197 | ECM | Lung | AIS | TAFA2,AGK,ATP1A1-AS1, etc. | 3.25e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_AIS/regulons_activity_in_dotplot.png) |
ZNF197 | ECM | Lung | IAC | TAFA2,AGK,ATP1A1-AS1, etc. | 1.20e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_IAC/regulons_activity_in_dotplot.png) |
ZNF197 | BN | Prostate | ADJ | TM9SF3,ATF7IP2,PKD2, etc. | 2.75e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Prostate/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF197 | BN | Prostate | BPH | TM9SF3,ATF7IP2,PKD2, etc. | 2.00e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Prostate/Str/TF_BPH/regulons_activity_in_dotplot.png) |
ZNF197 | PLA | Prostate | BPH | TM9SF3,ATF7IP2,PKD2, etc. | 3.87e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Prostate/Str/TF_BPH/regulons_activity_in_dotplot.png) |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF197 | SNV | Missense_Mutation | | c.426N>T | p.Gln142His | p.Q142H | O14709 | protein_coding | tolerated(0.07) | probably_damaging(0.976) | TCGA-BS-A0UV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | | c.2728G>T | p.Asp910Tyr | p.D910Y | O14709 | protein_coding | deleterious(0.03) | probably_damaging(0.979) | TCGA-D1-A103-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | | c.1930N>T | p.His644Tyr | p.H644Y | O14709 | protein_coding | deleterious(0) | probably_damaging(0.997) | TCGA-D1-A163-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | taxol | SD |
ZNF197 | SNV | Missense_Mutation | novel | c.1468N>A | p.Val490Ile | p.V490I | O14709 | protein_coding | tolerated(0.07) | possibly_damaging(0.747) | TCGA-D1-A175-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | paclitaxel | SD |
ZNF197 | SNV | Missense_Mutation | novel | c.617N>C | p.Leu206Pro | p.L206P | O14709 | protein_coding | tolerated(0.11) | probably_damaging(0.991) | TCGA-DF-A2KN-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | | c.2728N>T | p.Asp910Tyr | p.D910Y | O14709 | protein_coding | deleterious(0.03) | probably_damaging(0.979) | TCGA-DF-A2KU-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | rs371514033 | c.1232C>T | p.Ser411Leu | p.S411L | O14709 | protein_coding | deleterious(0) | probably_damaging(0.91) | TCGA-E6-A1LX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | | c.2597G>T | p.Arg866Ile | p.R866I | O14709 | protein_coding | tolerated(0.05) | probably_damaging(0.995) | TCGA-E6-A1LX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | novel | c.146N>A | p.Arg49His | p.R49H | O14709 | protein_coding | tolerated(0.21) | probably_damaging(0.996) | TCGA-EO-A22R-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | novel | c.2093N>T | p.Arg698Ile | p.R698I | O14709 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-EO-A22R-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |