Tissue | Expression Dynamics | Abbreviation |
Cervix | | CC: Cervix cancer |
HSIL_HPV: HPV-infected high-grade squamous intraepithelial lesions |
N_HPV: HPV-infected normal cervix |
Colorectum (GSE201348) | | FAP: Familial adenomatous polyposis |
CRC: Colorectal cancer |
Colorectum (HTA11) | | AD: Adenomas |
SER: Sessile serrated lesions |
MSI-H: Microsatellite-high colorectal cancer |
MSS: Microsatellite stable colorectal cancer |
Esophagus | | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias |
LGIN: Low-grade intraepithelial neoplasias |
GC | | CAG: Chronic atrophic gastritis |
CAG with IM: Chronic atrophic gastritis with intestinal metaplasia |
CSG: Chronic superficial gastritis |
GC: Gastric cancer |
SIM: Severe intestinal metaplasia |
WIM: Wild intestinal metaplasia |
Liver | | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
Lung | | AAH: Atypical adenomatous hyperplasia |
AIS: Adenocarcinoma in situ |
IAC: Invasive lung adenocarcinoma |
MIA: Minimally invasive adenocarcinoma |
Oral Cavity | | EOLP: Erosive Oral lichen planus |
LP: leukoplakia |
NEOLP: Non-erosive oral lichen planus |
OSCC: Oral squamous cell carcinoma |
Prostate | | BPH: Benign Prostatic Hyperplasia |
Skin | | AK: Actinic keratosis |
cSCC: Cutaneous squamous cell carcinoma |
SCCIS:squamous cell carcinoma in situ |
Thyroid | | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis |
PTC: Papillary thyroid cancer |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00975817 | Cervix | CC | lamellipodium organization | 31/2311 | 90/18723 | 4.57e-08 | 2.76e-06 | 31 |
GO:00300325 | Cervix | CC | lamellipodium assembly | 26/2311 | 72/18723 | 1.87e-07 | 8.48e-06 | 26 |
GO:009758112 | Cervix | HSIL_HPV | lamellipodium organization | 10/737 | 90/18723 | 2.81e-03 | 2.66e-02 | 10 |
GO:0097581 | Colorectum | AD | lamellipodium organization | 35/3918 | 90/18723 | 7.39e-05 | 1.18e-03 | 35 |
GO:0030032 | Colorectum | AD | lamellipodium assembly | 26/3918 | 72/18723 | 2.12e-03 | 1.68e-02 | 26 |
GO:00975811 | Colorectum | SER | lamellipodium organization | 24/2897 | 90/18723 | 4.33e-03 | 3.47e-02 | 24 |
GO:00975812 | Colorectum | MSS | lamellipodium organization | 33/3467 | 90/18723 | 3.70e-05 | 7.09e-04 | 33 |
GO:00300321 | Colorectum | MSS | lamellipodium assembly | 24/3467 | 72/18723 | 1.91e-03 | 1.66e-02 | 24 |
GO:00975813 | Colorectum | MSI-H | lamellipodium organization | 15/1319 | 90/18723 | 1.48e-03 | 2.23e-02 | 15 |
GO:00975814 | Colorectum | FAP | lamellipodium organization | 29/2622 | 90/18723 | 8.11e-06 | 2.40e-04 | 29 |
GO:00300322 | Colorectum | FAP | lamellipodium assembly | 22/2622 | 72/18723 | 2.31e-04 | 3.25e-03 | 22 |
GO:00975815 | Colorectum | CRC | lamellipodium organization | 28/2078 | 90/18723 | 2.43e-07 | 2.27e-05 | 28 |
GO:00300323 | Colorectum | CRC | lamellipodium assembly | 22/2078 | 72/18723 | 6.40e-06 | 2.47e-04 | 22 |
GO:009758116 | Esophagus | ESCC | lamellipodium organization | 53/8552 | 90/18723 | 7.92e-03 | 2.82e-02 | 53 |
GO:00975816 | Liver | NAFLD | lamellipodium organization | 22/1882 | 90/18723 | 6.25e-05 | 1.37e-03 | 22 |
GO:00300324 | Liver | NAFLD | lamellipodium assembly | 18/1882 | 72/18723 | 2.09e-04 | 3.60e-03 | 18 |
GO:009758111 | Liver | Cirrhotic | lamellipodium organization | 40/4634 | 90/18723 | 3.48e-05 | 4.26e-04 | 40 |
GO:003003211 | Liver | Cirrhotic | lamellipodium assembly | 30/4634 | 72/18723 | 1.18e-03 | 7.98e-03 | 30 |
GO:009758121 | Liver | HCC | lamellipodium organization | 58/7958 | 90/18723 | 2.16e-05 | 2.30e-04 | 58 |
GO:003003221 | Liver | HCC | lamellipodium assembly | 44/7958 | 72/18723 | 1.10e-03 | 6.32e-03 | 44 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ABLIM1 | SNV | Missense_Mutation | novel | c.1889N>T | p.Arg630Met | p.R630M | O14639 | protein_coding | deleterious(0) | benign(0.028) | TCGA-38-4626-01 | Lung | lung adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
ABLIM1 | SNV | Missense_Mutation | | c.2143N>T | p.Ile715Leu | p.I715L | O14639 | protein_coding | tolerated(0.07) | benign(0.078) | TCGA-44-2657-01 | Lung | lung adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ABLIM1 | SNV | Missense_Mutation | novel | c.1869G>A | p.Met623Ile | p.M623I | O14639 | protein_coding | tolerated(0.09) | benign(0.313) | TCGA-21-1079-01 | Lung | lung squamous cell carcinoma | Male | >=65 | III/IV | Unknown | Unknown | PD |
ABLIM1 | SNV | Missense_Mutation | rs768481591 | c.1333C>T | p.Arg445Trp | p.R445W | O14639 | protein_coding | deleterious(0.03) | possibly_damaging(0.872) | TCGA-21-1079-01 | Lung | lung squamous cell carcinoma | Male | >=65 | III/IV | Unknown | Unknown | PD |
ABLIM1 | SNV | Missense_Mutation | novel | c.649C>T | p.Pro217Ser | p.P217S | O14639 | protein_coding | tolerated(0.07) | benign(0) | TCGA-22-0944-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
ABLIM1 | SNV | Missense_Mutation | | c.247N>T | p.Ala83Ser | p.A83S | O14639 | protein_coding | tolerated(0.69) | benign(0.003) | TCGA-33-4566-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
ABLIM1 | SNV | Missense_Mutation | novel | c.238N>T | p.Pro80Ser | p.P80S | O14639 | protein_coding | tolerated(0.13) | benign(0.001) | TCGA-51-6867-01 | Lung | lung squamous cell carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
ABLIM1 | SNV | Missense_Mutation | novel | c.21N>A | p.Met7Ile | p.M7I | | protein_coding | tolerated_low_confidence(0.52) | benign(0) | TCGA-63-A5MP-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Chemotherapy | cisplatin | PD |
ABLIM1 | SNV | Missense_Mutation | novel | c.2198N>C | p.Arg733Thr | p.R733T | O14639 | protein_coding | deleterious(0) | benign(0.071) | TCGA-66-2768-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
ABLIM1 | SNV | Missense_Mutation | rs147888427 | c.469C>T | p.Arg157Cys | p.R157C | O14639 | protein_coding | deleterious(0) | probably_damaging(0.943) | TCGA-70-6722-01 | Lung | lung squamous cell carcinoma | Male | <65 | III/IV | Unknown | Unknown | PD |