TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
ZNF790 | MAST | Esophagus | Healthy | C12orf66,CREB1,ORMDL1, etc. | 5.08e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Esophagus/Str/TF_Healthy/regulons_activity_in_dotplot.png) |
ZNF790 | PLA | Esophagus | Healthy | C12orf66,CREB1,ORMDL1, etc. | 4.71e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Esophagus/Str/TF_Healthy/regulons_activity_in_dotplot.png) |
ZNF790 | CD8TEREX | Liver | Cirrhotic | FAM49A,ICE2,ANKRD36B, etc. | 1.68e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Liver/Str/TF_Cirrhotic/regulons_activity_in_dotplot.png) |
ZNF790 | CD8TEREX | Liver | HCC | FAM49A,ICE2,ANKRD36B, etc. | 2.40e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Liver/Str/TF_HCC/regulons_activity_in_dotplot.png) |
ZNF790 | PLA | Prostate | Healthy | EGFL7,AARS,AASDH, etc. | 2.29e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Prostate/Str/TF_Healthy/regulons_activity_in_dotplot.png) |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF790 | SNV | Missense_Mutation | novel | c.1145C>T | p.Ala382Val | p.A382V | Q6PG37 | protein_coding | tolerated(0.39) | benign(0.007) | TCGA-AX-A06F-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatin | SD |
ZNF790 | SNV | Missense_Mutation | novel | c.1830T>G | p.Ile610Met | p.I610M | Q6PG37 | protein_coding | tolerated(0.05) | possibly_damaging(0.842) | TCGA-AX-A0J0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | | c.1162C>A | p.His388Asn | p.H388N | Q6PG37 | protein_coding | deleterious(0) | probably_damaging(0.996) | TCGA-AX-A0J0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | | c.989G>T | p.Arg330Ile | p.R330I | Q6PG37 | protein_coding | deleterious(0.03) | probably_damaging(0.974) | TCGA-AX-A0J0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | novel | c.785N>T | p.Ala262Val | p.A262V | Q6PG37 | protein_coding | deleterious(0.01) | benign(0.328) | TCGA-AX-A2HD-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | rs528317660 | c.1652N>A | p.Arg551Gln | p.R551Q | Q6PG37 | protein_coding | tolerated(1) | benign(0) | TCGA-B5-A0JY-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | doxorubicin | SD |
ZNF790 | SNV | Missense_Mutation | novel | c.1546C>A | p.Leu516Ile | p.L516I | Q6PG37 | protein_coding | tolerated(0.44) | benign(0.026) | TCGA-B5-A11E-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | | c.1129C>T | p.Arg377Cys | p.R377C | Q6PG37 | protein_coding | tolerated(0.27) | benign(0.003) | TCGA-B5-A11E-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | novel | c.1564A>G | p.Thr522Ala | p.T522A | Q6PG37 | protein_coding | tolerated(0.22) | benign(0.011) | TCGA-B5-A3FA-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF790 | SNV | Missense_Mutation | rs551820063 | c.1304C>T | p.Ser435Leu | p.S435L | Q6PG37 | protein_coding | deleterious(0.02) | possibly_damaging(0.735) | TCGA-BK-A6W3-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |