GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:003166720 | Oral cavity | OSCC | response to nutrient levels | 245/7305 | 474/18723 | 1.02e-08 | 2.10e-07 | 245 |
GO:003010016 | Oral cavity | OSCC | regulation of endocytosis | 121/7305 | 211/18723 | 4.74e-08 | 8.80e-07 | 121 |
GO:004580710 | Oral cavity | OSCC | positive regulation of endocytosis | 59/7305 | 100/18723 | 3.99e-05 | 3.48e-04 | 59 |
GO:000689810 | Oral cavity | OSCC | receptor-mediated endocytosis | 125/7305 | 244/18723 | 6.56e-05 | 5.32e-04 | 125 |
GO:00725838 | Oral cavity | OSCC | clathrin-dependent endocytosis | 30/7305 | 47/18723 | 4.96e-04 | 2.92e-03 | 30 |
GO:004825910 | Oral cavity | OSCC | regulation of receptor-mediated endocytosis | 58/7305 | 110/18723 | 2.37e-03 | 1.05e-02 | 58 |
GO:003010023 | Oral cavity | EOLP | regulation of endocytosis | 51/2218 | 211/18723 | 4.24e-07 | 1.19e-05 | 51 |
GO:007258321 | Oral cavity | EOLP | clathrin-dependent endocytosis | 19/2218 | 47/18723 | 6.00e-07 | 1.56e-05 | 19 |
GO:000689825 | Oral cavity | EOLP | receptor-mediated endocytosis | 55/2218 | 244/18723 | 1.64e-06 | 3.82e-05 | 55 |
GO:004580724 | Oral cavity | EOLP | positive regulation of endocytosis | 27/2218 | 100/18723 | 2.69e-05 | 3.94e-04 | 27 |
GO:004825915 | Oral cavity | EOLP | regulation of receptor-mediated endocytosis | 28/2218 | 110/18723 | 6.12e-05 | 7.68e-04 | 28 |
GO:003166725 | Oral cavity | EOLP | response to nutrient levels | 82/2218 | 474/18723 | 2.59e-04 | 2.52e-03 | 82 |
GO:00482689 | Oral cavity | EOLP | clathrin coat assembly | 8/2218 | 18/18723 | 5.58e-04 | 4.74e-03 | 8 |
GO:00482609 | Oral cavity | EOLP | positive regulation of receptor-mediated endocytosis | 14/2218 | 52/18723 | 2.31e-03 | 1.42e-02 | 14 |
GO:003010031 | Oral cavity | NEOLP | regulation of endocytosis | 47/2005 | 211/18723 | 7.96e-07 | 2.20e-05 | 47 |
GO:000689831 | Oral cavity | NEOLP | receptor-mediated endocytosis | 51/2005 | 244/18723 | 2.08e-06 | 4.87e-05 | 51 |
GO:004580731 | Oral cavity | NEOLP | positive regulation of endocytosis | 27/2005 | 100/18723 | 4.19e-06 | 9.05e-05 | 27 |
GO:004826813 | Oral cavity | NEOLP | clathrin coat assembly | 9/2005 | 18/18723 | 3.59e-05 | 5.21e-04 | 9 |
GO:007258331 | Oral cavity | NEOLP | clathrin-dependent endocytosis | 15/2005 | 47/18723 | 7.12e-05 | 9.27e-04 | 15 |
GO:003166732 | Oral cavity | NEOLP | response to nutrient levels | 77/2005 | 474/18723 | 1.27e-04 | 1.49e-03 | 77 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
SGIP1 | SNV | Missense_Mutation | rs372902905 | c.115G>A | p.Glu39Lys | p.E39K | Q9BQI5 | protein_coding | tolerated_low_confidence(0.38) | benign(0.055) | TCGA-AP-A056-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SGIP1 | SNV | Missense_Mutation | | c.1196N>T | p.Ser399Phe | p.S399F | Q9BQI5 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.601) | TCGA-AP-A059-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
SGIP1 | SNV | Missense_Mutation | rs761517161 | c.908N>T | p.Ser303Phe | p.S303F | Q9BQI5 | protein_coding | deleterious_low_confidence(0.01) | probably_damaging(0.962) | TCGA-AP-A0LM-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | cisplatin | SD |
SGIP1 | SNV | Missense_Mutation | | c.2257N>A | p.Leu753Met | p.L753M | Q9BQI5 | protein_coding | deleterious(0.01) | possibly_damaging(0.808) | TCGA-AP-A0LN-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SGIP1 | SNV | Missense_Mutation | novel | c.2389N>G | p.Thr797Ala | p.T797A | Q9BQI5 | protein_coding | deleterious(0) | probably_damaging(0.962) | TCGA-AP-A1DK-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SGIP1 | SNV | Missense_Mutation | novel | c.281N>A | p.Gly94Asp | p.G94D | Q9BQI5 | protein_coding | tolerated(0.17) | probably_damaging(0.96) | TCGA-AP-A1DV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SGIP1 | SNV | Missense_Mutation | novel | c.1280N>A | p.Gly427Glu | p.G427E | Q9BQI5 | protein_coding | deleterious(0.03) | probably_damaging(0.994) | TCGA-AP-A1DV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SGIP1 | SNV | Missense_Mutation | novel | c.2099N>A | p.Ser700Asn | p.S700N | Q9BQI5 | protein_coding | tolerated(0.18) | benign(0.127) | TCGA-AP-A1DV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SGIP1 | SNV | Missense_Mutation | rs775231208 | c.1118C>T | p.Pro373Leu | p.P373L | Q9BQI5 | protein_coding | deleterious_low_confidence(0) | benign(0.005) | TCGA-AX-A2HA-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SGIP1 | SNV | Missense_Mutation | novel | c.71C>A | p.Ser24Tyr | p.S24Y | Q9BQI5 | protein_coding | deleterious(0) | probably_damaging(0.986) | TCGA-AX-A2HC-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | paclitaxel | PD |