TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
ZNF668 | BAS | Lung | AIS | ZSCAN30,SNX15,AC018816.1, etc. | 0.00e+00 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_AIS/regulons_activity_in_dotplot.png) |
ZNF668 | ABP | Lung | AIS | ZSCAN30,SNX15,AC018816.1, etc. | 1.87e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_AIS/regulons_activity_in_dotplot.png) |
ZNF668 | BAS | Lung | IAC | ZSCAN30,SNX15,AC018816.1, etc. | 1.12e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_IAC/regulons_activity_in_dotplot.png) |
ZNF668 | ABP | Lung | MIAC | ZSCAN30,SNX15,AC018816.1, etc. | 1.88e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_MIAC/regulons_activity_in_dotplot.png) |
ZNF668 | BAS | Lung | MIAC | ZSCAN30,SNX15,AC018816.1, etc. | 4.44e-16 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_MIAC/regulons_activity_in_dotplot.png) |
ZNF668 | ECM | Oral cavity | LP | GPR1,HSD3B7,HTRA3, etc. | 3.73e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_LP/regulons_activity_in_dotplot.png) |
ZNF668 | PERI | Stomach | ADJ | LINC01278,GCNT2,PMM1, etc. | 1.80e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF668 | SMC | Stomach | CAG | LINC01278,GCNT2,PMM1, etc. | 3.85e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_CAG/regulons_activity_in_dotplot.png) |
ZNF668 | MSC | Stomach | CAG with IM | LINC01278,GCNT2,PMM1, etc. | 1.18e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_CAG with IM/regulons_activity_in_dotplot.png) |
ZNF668 | LYMEND | Stomach | SIM | LINC01278,GCNT2,PMM1, etc. | 1.89e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_SIM/regulons_activity_in_dotplot.png) |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF668 | SNV | Missense_Mutation | rs75415004 | c.1177N>A | p.Gly393Arg | p.G393R | Q96K58 | protein_coding | deleterious(0.01) | probably_damaging(1) | TCGA-DF-A2KN-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |
ZNF668 | SNV | Missense_Mutation | | c.632N>A | p.Arg211His | p.R211H | Q96K58 | protein_coding | deleterious(0.01) | probably_damaging(0.938) | TCGA-EC-A24G-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | doxorubicin | SD |
ZNF668 | SNV | Missense_Mutation | novel | c.1265N>C | p.Lys422Thr | p.K422T | Q96K58 | protein_coding | deleterious(0) | probably_damaging(0.998) | TCGA-EY-A1GI-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF668 | SNV | Missense_Mutation | novel | c.704G>A | p.Arg235His | p.R235H | Q96K58 | protein_coding | deleterious(0.03) | benign(0.034) | TCGA-EY-A215-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF668 | SNV | Missense_Mutation | novel | c.1912N>A | p.Glu638Lys | p.E638K | Q96K58 | protein_coding | tolerated_low_confidence(0.06) | benign(0.163) | TCGA-EY-A5W2-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF668 | SNV | Missense_Mutation | novel | c.32A>G | p.Asp11Gly | p.D11G | Q96K58 | protein_coding | tolerated_low_confidence(0.05) | unknown(0) | TCGA-FI-A2D5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatinum | PD |
ZNF668 | SNV | Missense_Mutation | novel | c.788C>T | p.Thr263Met | p.T263M | Q96K58 | protein_coding | deleterious(0.03) | probably_damaging(0.965) | TCGA-SJ-A6ZI-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF668 | SNV | Missense_Mutation | rs759082830 | c.451C>T | p.Arg151Cys | p.R151C | Q96K58 | protein_coding | deleterious(0) | probably_damaging(0.984) | TCGA-SJ-A6ZI-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF668 | deletion | Frame_Shift_Del | rs770091266 | c.1612delN | p.Gln538SerfsTer14 | p.Q538Sfs*14 | Q96K58 | protein_coding | | | TCGA-AX-A2HD-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
ZNF668 | deletion | Frame_Shift_Del | rs770091266 | c.1612delN | p.Gln538SerfsTer14 | p.Q538Sfs*14 | Q96K58 | protein_coding | | | TCGA-AX-A2IN-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | PD |