GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:005160410 | Oral cavity | OSCC | protein maturation | 170/7305 | 294/18723 | 3.97e-11 | 1.28e-09 | 170 |
GO:004578520 | Oral cavity | OSCC | positive regulation of cell adhesion | 225/7305 | 437/18723 | 6.06e-08 | 1.09e-06 | 225 |
GO:000189017 | Oral cavity | OSCC | placenta development | 87/7305 | 144/18723 | 1.54e-07 | 2.56e-06 | 87 |
GO:006145817 | Oral cavity | OSCC | reproductive system development | 217/7305 | 427/18723 | 3.75e-07 | 5.63e-06 | 217 |
GO:004860816 | Oral cavity | OSCC | reproductive structure development | 214/7305 | 424/18723 | 8.58e-07 | 1.18e-05 | 214 |
GO:00164856 | Oral cavity | OSCC | protein processing | 121/7305 | 225/18723 | 4.56e-06 | 5.23e-05 | 121 |
GO:002240718 | Oral cavity | OSCC | regulation of cell-cell adhesion | 218/7305 | 448/18723 | 1.71e-05 | 1.68e-04 | 218 |
GO:00336194 | Oral cavity | OSCC | membrane protein proteolysis | 37/7305 | 57/18723 | 6.66e-05 | 5.38e-04 | 37 |
GO:00065094 | Oral cavity | OSCC | membrane protein ectodomain proteolysis | 29/7305 | 43/18723 | 1.49e-04 | 1.05e-03 | 29 |
GO:00429873 | Oral cavity | OSCC | amyloid precursor protein catabolic process | 40/7305 | 68/18723 | 7.28e-04 | 3.98e-03 | 40 |
GO:00429823 | Oral cavity | OSCC | amyloid precursor protein metabolic process | 52/7305 | 95/18723 | 1.33e-03 | 6.62e-03 | 52 |
GO:002240917 | Oral cavity | OSCC | positive regulation of cell-cell adhesion | 136/7305 | 284/18723 | 1.35e-03 | 6.62e-03 | 136 |
GO:004578526 | Oral cavity | EOLP | positive regulation of cell adhesion | 95/2218 | 437/18723 | 2.30e-09 | 1.47e-07 | 95 |
GO:002240719 | Oral cavity | EOLP | regulation of cell-cell adhesion | 93/2218 | 448/18723 | 3.65e-08 | 1.41e-06 | 93 |
GO:000189023 | Oral cavity | EOLP | placenta development | 39/2218 | 144/18723 | 4.49e-07 | 1.25e-05 | 39 |
GO:006145824 | Oral cavity | EOLP | reproductive system development | 81/2218 | 427/18723 | 1.09e-05 | 1.93e-04 | 81 |
GO:004860823 | Oral cavity | EOLP | reproductive structure development | 80/2218 | 424/18723 | 1.51e-05 | 2.50e-04 | 80 |
GO:002240918 | Oral cavity | EOLP | positive regulation of cell-cell adhesion | 57/2218 | 284/18723 | 4.23e-05 | 5.77e-04 | 57 |
GO:003361921 | Oral cavity | EOLP | membrane protein proteolysis | 16/2218 | 57/18723 | 7.07e-04 | 5.78e-03 | 16 |
GO:000650912 | Oral cavity | EOLP | membrane protein ectodomain proteolysis | 13/2218 | 43/18723 | 1.03e-03 | 7.63e-03 | 13 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ADAM19 | deletion | Frame_Shift_Del | | c.2381delC | p.Pro794LeufsTer18 | p.P794Lfs*18 | Q9H013 | protein_coding | | | TCGA-AA-3833-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ADAM19 | SNV | Missense_Mutation | novel | c.1909N>T | p.Ile637Phe | p.I637F | Q9H013 | protein_coding | deleterious(0) | possibly_damaging(0.885) | TCGA-A5-A0G1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ADAM19 | SNV | Missense_Mutation | novel | c.184N>T | p.Pro62Ser | p.P62S | Q9H013 | protein_coding | deleterious(0.02) | benign(0.103) | TCGA-A5-A0G2-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
ADAM19 | SNV | Missense_Mutation | rs759459737 | c.1828G>A | p.Val610Ile | p.V610I | Q9H013 | protein_coding | deleterious(0.04) | possibly_damaging(0.584) | TCGA-A5-A1OF-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ADAM19 | SNV | Missense_Mutation | novel | c.2737A>G | p.Met913Val | p.M913V | Q9H013 | protein_coding | tolerated_low_confidence(0.34) | benign(0) | TCGA-A5-A1OH-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | III/IV | Chemotherapy | carboplatin | CR |
ADAM19 | SNV | Missense_Mutation | novel | c.1221N>A | p.Met407Ile | p.M407I | Q9H013 | protein_coding | deleterious(0.03) | benign(0.048) | TCGA-AJ-A3BG-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Chemotherapy | carboplatin | PD |
ADAM19 | SNV | Missense_Mutation | rs746671789 | c.2741N>C | p.Ile914Thr | p.I914T | Q9H013 | protein_coding | tolerated_low_confidence(1) | benign(0) | TCGA-AJ-A3EL-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ADAM19 | SNV | Missense_Mutation | rs147812090 | c.590G>A | p.Arg197Gln | p.R197Q | Q9H013 | protein_coding | tolerated(0.35) | benign(0.007) | TCGA-AP-A0LM-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | cisplatin | SD |
ADAM19 | SNV | Missense_Mutation | | c.1096N>A | p.Ala366Thr | p.A366T | Q9H013 | protein_coding | deleterious(0.03) | possibly_damaging(0.462) | TCGA-AP-A1DK-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ADAM19 | SNV | Missense_Mutation | novel | c.2613N>T | p.Arg871Ser | p.R871S | Q9H013 | protein_coding | tolerated(0.32) | benign(0.116) | TCGA-AP-A1DV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |