GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00182057 | Esophagus | HGIN | peptidyl-lysine modification | 88/2587 | 376/18723 | 2.99e-07 | 1.39e-05 | 88 |
GO:000632516 | Esophagus | HGIN | chromatin organization | 92/2587 | 409/18723 | 1.05e-06 | 4.16e-05 | 92 |
GO:00165708 | Esophagus | HGIN | histone modification | 92/2587 | 463/18723 | 1.70e-04 | 3.30e-03 | 92 |
GO:00064735 | Esophagus | HGIN | protein acetylation | 45/2587 | 201/18723 | 6.17e-04 | 8.58e-03 | 45 |
GO:00183945 | Esophagus | HGIN | peptidyl-lysine acetylation | 39/2587 | 169/18723 | 7.46e-04 | 9.90e-03 | 39 |
GO:00435435 | Esophagus | HGIN | protein acylation | 51/2587 | 243/18723 | 1.33e-03 | 1.57e-02 | 51 |
GO:00064755 | Esophagus | HGIN | internal protein amino acid acetylation | 36/2587 | 160/18723 | 1.87e-03 | 2.01e-02 | 36 |
GO:00183935 | Esophagus | HGIN | internal peptidyl-lysine acetylation | 35/2587 | 158/18723 | 2.82e-03 | 2.75e-02 | 35 |
GO:001657015 | Esophagus | ESCC | histone modification | 323/8552 | 463/18723 | 2.61e-26 | 7.88e-24 | 323 |
GO:001820514 | Esophagus | ESCC | peptidyl-lysine modification | 259/8552 | 376/18723 | 3.90e-20 | 5.26e-18 | 259 |
GO:001839413 | Esophagus | ESCC | peptidyl-lysine acetylation | 123/8552 | 169/18723 | 6.58e-13 | 2.94e-11 | 123 |
GO:004354313 | Esophagus | ESCC | protein acylation | 165/8552 | 243/18723 | 1.69e-12 | 7.14e-11 | 165 |
GO:000647313 | Esophagus | ESCC | protein acetylation | 140/8552 | 201/18723 | 4.37e-12 | 1.69e-10 | 140 |
GO:001839313 | Esophagus | ESCC | internal peptidyl-lysine acetylation | 114/8552 | 158/18723 | 1.16e-11 | 4.24e-10 | 114 |
GO:000647513 | Esophagus | ESCC | internal protein amino acid acetylation | 115/8552 | 160/18723 | 1.43e-11 | 5.08e-10 | 115 |
GO:00165735 | Esophagus | ESCC | histone acetylation | 110/8552 | 152/18723 | 1.95e-11 | 6.81e-10 | 110 |
GO:000632517 | Esophagus | ESCC | chromatin organization | 240/8552 | 409/18723 | 6.52e-08 | 1.14e-06 | 240 |
GO:0043486 | Esophagus | ESCC | histone exchange | 16/8552 | 22/18723 | 9.46e-03 | 3.28e-02 | 16 |
GO:001657021 | Liver | HCC | histone modification | 283/7958 | 463/18723 | 2.68e-16 | 2.33e-14 | 283 |
GO:00182052 | Liver | HCC | peptidyl-lysine modification | 230/7958 | 376/18723 | 1.51e-13 | 8.32e-12 | 230 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
SRCAP | SNV | Missense_Mutation | rs755641907 | c.7282C>T | p.Arg2428Cys | p.R2428C | Q6ZRS2 | protein_coding | deleterious_low_confidence(0) | benign(0) | TCGA-66-2794-01 | Lung | lung squamous cell carcinoma | Male | <65 | III/IV | Unknown | Unknown | SD |
SRCAP | SNV | Missense_Mutation | novel | c.8441N>T | p.Ser2814Leu | p.S2814L | Q6ZRS2 | protein_coding | tolerated_low_confidence(0.18) | benign(0) | TCGA-77-7141-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
SRCAP | SNV | Missense_Mutation | rs748534359 | c.3098C>T | p.Ser1033Leu | p.S1033L | Q6ZRS2 | protein_coding | tolerated(0.07) | benign(0.122) | TCGA-77-A5GB-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |
SRCAP | SNV | Missense_Mutation | novel | c.974N>T | p.Arg325Leu | p.R325L | Q6ZRS2 | protein_coding | deleterious(0.02) | benign(0.199) | TCGA-85-8350-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
SRCAP | SNV | Missense_Mutation | novel | c.8428N>A | p.Glu2810Lys | p.E2810K | Q6ZRS2 | protein_coding | deleterious_low_confidence(0.01) | benign(0.001) | TCGA-98-8021-01 | Lung | lung squamous cell carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
SRCAP | SNV | Missense_Mutation | | c.7802N>G | p.Ser2601Cys | p.S2601C | Q6ZRS2 | protein_coding | deleterious_low_confidence(0.03) | benign(0.319) | TCGA-98-A53A-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
SRCAP | deletion | Frame_Shift_Del | | c.4786_4790delNNNNN | p.Ala1596SerfsTer250 | p.A1596Sfs*250 | Q6ZRS2 | protein_coding | | | TCGA-49-AARE-01 | Lung | lung adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
SRCAP | deletion | Frame_Shift_Del | | c.3172delN | p.Pro1059ArgfsTer35 | p.P1059Rfs*35 | Q6ZRS2 | protein_coding | | | TCGA-55-8507-01 | Lung | lung adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
SRCAP | deletion | Frame_Shift_Del | | c.3562delN | p.Gln1189SerfsTer2 | p.Q1189Sfs*2 | Q6ZRS2 | protein_coding | | | TCGA-MP-A4TA-01 | Lung | lung adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
SRCAP | SNV | Missense_Mutation | novel | c.628N>A | p.Glu210Lys | p.E210K | Q6ZRS2 | protein_coding | deleterious(0.01) | probably_damaging(0.994) | TCGA-CN-A6V3-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Chemotherapy | cisplatin | CR |