GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0016032111 | Esophagus | ESCC | viral process | 301/8552 | 415/18723 | 3.34e-29 | 1.32e-26 | 301 |
GO:0019058111 | Esophagus | ESCC | viral life cycle | 226/8552 | 317/18723 | 1.17e-20 | 1.76e-18 | 226 |
GO:001908017 | Esophagus | ESCC | viral gene expression | 80/8552 | 94/18723 | 2.04e-15 | 1.28e-13 | 80 |
GO:0016049110 | Esophagus | ESCC | cell growth | 289/8552 | 482/18723 | 1.29e-10 | 3.77e-09 | 289 |
GO:0044403111 | Esophagus | ESCC | biological process involved in symbiotic interaction | 186/8552 | 290/18723 | 1.43e-10 | 4.16e-09 | 186 |
GO:0051701111 | Esophagus | ESCC | biological process involved in interaction with host | 135/8552 | 203/18723 | 1.49e-09 | 3.49e-08 | 135 |
GO:000155819 | Esophagus | ESCC | regulation of cell growth | 248/8552 | 414/18723 | 2.97e-09 | 6.45e-08 | 248 |
GO:0052126111 | Esophagus | ESCC | movement in host environment | 117/8552 | 175/18723 | 1.14e-08 | 2.26e-07 | 117 |
GO:001908312 | Esophagus | ESCC | viral transcription | 41/8552 | 50/18723 | 1.35e-07 | 2.17e-06 | 41 |
GO:0044409111 | Esophagus | ESCC | entry into host | 96/8552 | 151/18723 | 6.73e-06 | 6.84e-05 | 96 |
GO:005185115 | Esophagus | ESCC | modulation by host of symbiont process | 43/8552 | 60/18723 | 4.00e-05 | 3.22e-04 | 43 |
GO:004671827 | Esophagus | ESCC | viral entry into host cell | 89/8552 | 144/18723 | 6.84e-05 | 5.18e-04 | 89 |
GO:003030710 | Esophagus | ESCC | positive regulation of cell growth | 100/8552 | 166/18723 | 1.07e-04 | 7.55e-04 | 100 |
GO:005181714 | Esophagus | ESCC | modulation of process of other organism involved in symbiotic interaction | 54/8552 | 81/18723 | 1.09e-04 | 7.64e-04 | 54 |
GO:00439233 | Esophagus | ESCC | positive regulation by host of viral transcription | 14/8552 | 16/18723 | 6.78e-04 | 3.56e-03 | 14 |
GO:003582114 | Esophagus | ESCC | modulation of process of other organism | 64/8552 | 106/18723 | 1.61e-03 | 7.50e-03 | 64 |
GO:005170214 | Esophagus | ESCC | biological process involved in interaction with symbiont | 57/8552 | 94/18723 | 2.46e-03 | 1.07e-02 | 57 |
GO:00439224 | Esophagus | ESCC | negative regulation by host of viral transcription | 12/8552 | 14/18723 | 2.51e-03 | 1.08e-02 | 12 |
GO:004592717 | Esophagus | ESCC | positive regulation of growth | 137/8552 | 259/18723 | 1.13e-02 | 3.80e-02 | 137 |
GO:001603222 | Liver | HCC | viral process | 286/7958 | 415/18723 | 4.41e-28 | 1.86e-25 | 286 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF639 | SNV | Missense_Mutation | | c.319N>G | p.Ile107Val | p.I107V | Q9UID6 | protein_coding | tolerated(0.94) | benign(0) | TCGA-B5-A11Y-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF639 | SNV | Missense_Mutation | novel | c.733N>G | p.Asn245Asp | p.N245D | Q9UID6 | protein_coding | deleterious(0.04) | benign(0.209) | TCGA-D1-A175-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | paclitaxel | SD |
ZNF639 | SNV | Missense_Mutation | novel | c.1199N>A | p.Ile400Asn | p.I400N | Q9UID6 | protein_coding | tolerated(0.44) | possibly_damaging(0.728) | TCGA-DF-A2KN-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |
ZNF639 | SNV | Missense_Mutation | | c.1313N>G | p.Tyr438Cys | p.Y438C | Q9UID6 | protein_coding | deleterious(0.01) | probably_damaging(0.99) | TCGA-DI-A1BU-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | paclitaxel | SD |
ZNF639 | SNV | Missense_Mutation | novel | c.1028A>C | p.Lys343Thr | p.K343T | Q9UID6 | protein_coding | deleterious(0.03) | benign(0.029) | TCGA-E6-A1LX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF639 | SNV | Missense_Mutation | novel | c.149T>C | p.Leu50Ser | p.L50S | Q9UID6 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.986) | TCGA-EC-A24G-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Chemotherapy | doxorubicin | SD |
ZNF639 | SNV | Missense_Mutation | novel | c.35N>A | p.Thr12Asn | p.T12N | Q9UID6 | protein_coding | deleterious_low_confidence(0.01) | possibly_damaging(0.829) | TCGA-EO-A22U-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF639 | SNV | Missense_Mutation | novel | c.894N>A | p.Phe298Leu | p.F298L | Q9UID6 | protein_coding | deleterious(0.03) | probably_damaging(0.973) | TCGA-EO-A22U-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF639 | SNV | Missense_Mutation | rs767153760 | c.1144N>T | p.Arg382Trp | p.R382W | Q9UID6 | protein_coding | deleterious(0.03) | possibly_damaging(0.825) | TCGA-EO-A3AY-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
ZNF639 | SNV | Missense_Mutation | novel | c.1366N>A | p.Ala456Thr | p.A456T | Q9UID6 | protein_coding | tolerated(0.15) | benign(0) | TCGA-FI-A2D0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |