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Gene: ZMYND19 |
Gene summary for ZMYND19 |
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Gene information | Species | Human | Gene symbol | ZMYND19 | Gene ID | 116225 |
Gene name | zinc finger MYND-type containing 19 | |
Gene Alias | MIZIP | |
Cytomap | 9q34.3 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q96E35 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
116225 | ZMYND19 | HCC1_Meng | Human | Liver | HCC | 2.05e-23 | 3.18e-02 | 0.0246 |
116225 | ZMYND19 | HCC2_Meng | Human | Liver | HCC | 1.65e-03 | 4.19e-02 | 0.0107 |
116225 | ZMYND19 | HCC1 | Human | Liver | HCC | 3.12e-03 | 1.33e+00 | 0.5336 |
116225 | ZMYND19 | HCC2 | Human | Liver | HCC | 6.20e-03 | 8.28e-01 | 0.5341 |
116225 | ZMYND19 | S014 | Human | Liver | HCC | 1.64e-05 | 1.89e-01 | 0.2254 |
116225 | ZMYND19 | S015 | Human | Liver | HCC | 2.74e-02 | 1.13e-01 | 0.2375 |
116225 | ZMYND19 | S016 | Human | Liver | HCC | 8.17e-08 | 1.85e-01 | 0.2243 |
116225 | ZMYND19 | S027 | Human | Liver | HCC | 1.62e-09 | 4.21e-01 | 0.2446 |
116225 | ZMYND19 | S028 | Human | Liver | HCC | 4.40e-18 | 4.76e-01 | 0.2503 |
116225 | ZMYND19 | S029 | Human | Liver | HCC | 1.35e-19 | 5.09e-01 | 0.2581 |
116225 | ZMYND19 | C04 | Human | Oral cavity | OSCC | 1.31e-02 | 2.26e-01 | 0.2633 |
116225 | ZMYND19 | C21 | Human | Oral cavity | OSCC | 4.34e-13 | 4.93e-01 | 0.2678 |
116225 | ZMYND19 | C30 | Human | Oral cavity | OSCC | 1.65e-32 | 1.31e+00 | 0.3055 |
116225 | ZMYND19 | C38 | Human | Oral cavity | OSCC | 2.09e-02 | 4.03e-01 | 0.172 |
116225 | ZMYND19 | C43 | Human | Oral cavity | OSCC | 4.38e-06 | 1.47e-01 | 0.1704 |
116225 | ZMYND19 | C46 | Human | Oral cavity | OSCC | 2.25e-02 | 1.23e-01 | 0.1673 |
116225 | ZMYND19 | C06 | Human | Oral cavity | OSCC | 2.98e-02 | 7.25e-01 | 0.2699 |
116225 | ZMYND19 | C08 | Human | Oral cavity | OSCC | 4.65e-07 | 2.57e-01 | 0.1919 |
116225 | ZMYND19 | C09 | Human | Oral cavity | OSCC | 1.48e-02 | 1.08e-01 | 0.1431 |
116225 | ZMYND19 | LN22 | Human | Oral cavity | OSCC | 5.60e-03 | 5.60e-01 | 0.1733 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZMYND19 | deletion | Frame_Shift_Del | rs759203218 | c.236delG | p.Gly79AlafsTer14 | p.G79Afs*14 | Q96E35 | protein_coding | TCGA-VQ-A924-01 | Stomach | stomach adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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