GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0016032111 | Esophagus | ESCC | viral process | 301/8552 | 415/18723 | 3.34e-29 | 1.32e-26 | 301 |
GO:0019058111 | Esophagus | ESCC | viral life cycle | 226/8552 | 317/18723 | 1.17e-20 | 1.76e-18 | 226 |
GO:000734615 | Esophagus | ESCC | regulation of mitotic cell cycle | 293/8552 | 457/18723 | 8.00e-16 | 5.64e-14 | 293 |
GO:0050792111 | Esophagus | ESCC | regulation of viral process | 119/8552 | 164/18723 | 2.19e-12 | 9.03e-11 | 119 |
GO:1903900111 | Esophagus | ESCC | regulation of viral life cycle | 106/8552 | 148/18723 | 1.26e-10 | 3.72e-09 | 106 |
GO:0044403111 | Esophagus | ESCC | biological process involved in symbiotic interaction | 186/8552 | 290/18723 | 1.43e-10 | 4.16e-09 | 186 |
GO:00457865 | Esophagus | ESCC | negative regulation of cell cycle | 236/8552 | 385/18723 | 3.62e-10 | 9.93e-09 | 236 |
GO:0051701111 | Esophagus | ESCC | biological process involved in interaction with host | 135/8552 | 203/18723 | 1.49e-09 | 3.49e-08 | 135 |
GO:0052126111 | Esophagus | ESCC | movement in host environment | 117/8552 | 175/18723 | 1.14e-08 | 2.26e-07 | 117 |
GO:004852516 | Esophagus | ESCC | negative regulation of viral process | 66/8552 | 92/18723 | 3.49e-07 | 4.88e-06 | 66 |
GO:004593013 | Esophagus | ESCC | negative regulation of mitotic cell cycle | 143/8552 | 235/18723 | 1.84e-06 | 2.15e-05 | 143 |
GO:001907614 | Esophagus | ESCC | viral release from host cell | 28/8552 | 34/18723 | 1.21e-05 | 1.12e-04 | 28 |
GO:003589014 | Esophagus | ESCC | exit from host | 28/8552 | 34/18723 | 1.21e-05 | 1.12e-04 | 28 |
GO:003589114 | Esophagus | ESCC | exit from host cell | 28/8552 | 34/18723 | 1.21e-05 | 1.12e-04 | 28 |
GO:0043903111 | Esophagus | ESCC | regulation of biological process involved in symbiotic interaction | 49/8552 | 72/18723 | 1.03e-04 | 7.26e-04 | 49 |
GO:19021864 | Esophagus | ESCC | regulation of viral release from host cell | 20/8552 | 26/18723 | 1.19e-03 | 5.88e-03 | 20 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
TRIM35 | SNV | Missense_Mutation | novel | c.1277N>A | p.Arg426His | p.R426H | Q9UPQ4 | protein_coding | deleterious(0.02) | benign(0.005) | TCGA-AJ-A3NE-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TRIM35 | SNV | Missense_Mutation | | c.511N>A | p.Ala171Thr | p.A171T | Q9UPQ4 | protein_coding | tolerated(0.3) | benign(0.015) | TCGA-AP-A051-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TRIM35 | SNV | Missense_Mutation | novel | c.1048N>A | p.Val350Ile | p.V350I | Q9UPQ4 | protein_coding | tolerated(0.08) | benign(0.003) | TCGA-AP-A059-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TRIM35 | SNV | Missense_Mutation | rs774997405 | c.517N>A | p.Ala173Thr | p.A173T | Q9UPQ4 | protein_coding | tolerated(0.08) | benign(0.012) | TCGA-AX-A0J1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TRIM35 | SNV | Missense_Mutation | | c.719G>A | p.Arg240Gln | p.R240Q | Q9UPQ4 | protein_coding | tolerated(0.79) | benign(0.073) | TCGA-AX-A2HD-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
TRIM35 | SNV | Missense_Mutation | rs776766188 | c.970N>A | p.Val324Ile | p.V324I | Q9UPQ4 | protein_coding | tolerated(0.15) | benign(0.442) | TCGA-AX-A3G9-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatin | SD |
TRIM35 | SNV | Missense_Mutation | rs774997405 | c.517G>A | p.Ala173Thr | p.A173T | Q9UPQ4 | protein_coding | tolerated(0.08) | benign(0.012) | TCGA-B5-A3FC-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TRIM35 | SNV | Missense_Mutation | rs749591000 | c.958G>A | p.Asp320Asn | p.D320N | Q9UPQ4 | protein_coding | tolerated(0.05) | benign(0.071) | TCGA-BS-A0U8-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | doxorubicin | SD |
TRIM35 | SNV | Missense_Mutation | rs776766188 | c.970N>A | p.Val324Ile | p.V324I | Q9UPQ4 | protein_coding | tolerated(0.15) | benign(0.442) | TCGA-D1-A103-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TRIM35 | SNV | Missense_Mutation | rs201505344 | c.745N>A | p.Asp249Asn | p.D249N | Q9UPQ4 | protein_coding | tolerated(0.07) | benign(0.397) | TCGA-D1-A103-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |