GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00464863 | Liver | NAFLD | glycerolipid metabolic process | 66/1882 | 392/18723 | 1.94e-05 | 5.52e-04 | 66 |
GO:00450174 | Liver | NAFLD | glycerolipid biosynthetic process | 43/1882 | 252/18723 | 3.83e-04 | 5.73e-03 | 43 |
GO:00464742 | Liver | NAFLD | glycerophospholipid biosynthetic process | 33/1882 | 211/18723 | 6.93e-03 | 4.88e-02 | 33 |
GO:00086542 | Liver | HCC | phospholipid biosynthetic process | 150/7958 | 253/18723 | 4.77e-08 | 1.03e-06 | 150 |
GO:00066444 | Liver | HCC | phospholipid metabolic process | 214/7958 | 383/18723 | 7.25e-08 | 1.48e-06 | 214 |
GO:004648611 | Liver | HCC | glycerolipid metabolic process | 215/7958 | 392/18723 | 4.54e-07 | 7.49e-06 | 215 |
GO:004501711 | Liver | HCC | glycerolipid biosynthetic process | 143/7958 | 252/18723 | 3.27e-06 | 4.31e-05 | 143 |
GO:00066504 | Liver | HCC | glycerophospholipid metabolic process | 168/7958 | 306/18723 | 7.27e-06 | 8.62e-05 | 168 |
GO:004647411 | Liver | HCC | glycerophospholipid biosynthetic process | 121/7958 | 211/18723 | 9.12e-06 | 1.06e-04 | 121 |
GO:0006661 | Liver | HCC | phosphatidylinositol biosynthetic process | 69/7958 | 131/18723 | 1.19e-02 | 4.35e-02 | 69 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
SOCS7 | SNV | Missense_Mutation | novel | c.806N>T | p.Arg269Ile | p.R269I | O14512 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.994) | TCGA-DF-A2KV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SOCS7 | SNV | Missense_Mutation | novel | c.1462N>A | p.Leu488Ile | p.L488I | O14512 | protein_coding | deleterious(0.01) | benign(0.351) | TCGA-E6-A1LX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SOCS7 | SNV | Missense_Mutation | novel | c.663N>T | p.Lys221Asn | p.K221N | O14512 | protein_coding | deleterious_low_confidence(0) | benign(0) | TCGA-EO-A22R-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
SOCS7 | SNV | Missense_Mutation | rs764623857 | c.1399C>T | p.Arg467Cys | p.R467C | O14512 | protein_coding | deleterious(0.01) | benign(0.312) | TCGA-55-7995-01 | Lung | lung adenocarcinoma | Female | >=65 | I/II | Chemotherapy | carboplatin | CR |
SOCS7 | deletion | Frame_Shift_Del | novel | c.1100delN | p.Leu368CysfsTer38 | p.L368Cfs*38 | O14512 | protein_coding | | | TCGA-56-7822-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Chemotherapy | eloxatin | PD |
SOCS7 | SNV | Missense_Mutation | novel | c.887N>G | p.Ser296Cys | p.S296C | O14512 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.997) | TCGA-CV-5432-01 | Oral cavity | head & neck squamous cell carcinoma | Male | >=65 | III/IV | Unknown | Unknown | SD |
SOCS7 | SNV | Missense_Mutation | novel | c.1138C>A | p.Leu380Ile | p.L380I | O14512 | protein_coding | deleterious(0.02) | benign(0.046) | TCGA-CV-6933-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | III/IV | Unknown | Unknown | SD |
SOCS7 | SNV | Missense_Mutation | rs370033423 | c.1145N>A | p.Arg382Gln | p.R382Q | O14512 | protein_coding | deleterious(0.02) | benign(0.289) | TCGA-MT-A67D-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
SOCS7 | SNV | Missense_Mutation | novel | c.1109N>A | p.Ser370Asn | p.S370N | O14512 | protein_coding | tolerated(0.43) | benign(0) | TCGA-CG-4465-01 | Stomach | stomach adenocarcinoma | Female | >=65 | III/IV | Chemotherapy | cisplatin | SD |
SOCS7 | SNV | Missense_Mutation | rs145376452 | c.1037N>T | p.Pro346Leu | p.P346L | O14512 | protein_coding | tolerated(0.45) | benign(0.013) | TCGA-HU-8244-01 | Stomach | stomach adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |