GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0022411111 | Esophagus | ESCC | cellular component disassembly | 305/8552 | 443/18723 | 1.94e-23 | 4.57e-21 | 305 |
GO:005165617 | Esophagus | ESCC | establishment of organelle localization | 273/8552 | 390/18723 | 9.13e-23 | 1.81e-20 | 273 |
GO:003298416 | Esophagus | ESCC | protein-containing complex disassembly | 151/8552 | 224/18723 | 3.45e-11 | 1.15e-09 | 151 |
GO:1902903111 | Esophagus | ESCC | regulation of supramolecular fiber organization | 237/8552 | 383/18723 | 9.06e-11 | 2.75e-09 | 237 |
GO:003070518 | Esophagus | ESCC | cytoskeleton-dependent intracellular transport | 133/8552 | 195/18723 | 1.48e-10 | 4.27e-09 | 133 |
GO:001097013 | Esophagus | ESCC | transport along microtubule | 107/8552 | 155/18723 | 3.17e-09 | 6.80e-08 | 107 |
GO:00723846 | Esophagus | ESCC | organelle transport along microtubule | 65/8552 | 85/18723 | 6.61e-09 | 1.35e-07 | 65 |
GO:000632517 | Esophagus | ESCC | chromatin organization | 240/8552 | 409/18723 | 6.52e-08 | 1.14e-06 | 240 |
GO:00705078 | Esophagus | ESCC | regulation of microtubule cytoskeleton organization | 99/8552 | 148/18723 | 1.43e-07 | 2.29e-06 | 99 |
GO:00991114 | Esophagus | ESCC | microtubule-based transport | 115/8552 | 190/18723 | 2.54e-05 | 2.15e-04 | 115 |
GO:005165411 | Esophagus | ESCC | establishment of mitochondrion localization | 24/8552 | 29/18723 | 4.50e-05 | 3.55e-04 | 24 |
GO:00311094 | Esophagus | ESCC | microtubule polymerization or depolymerization | 77/8552 | 122/18723 | 7.60e-05 | 5.68e-04 | 77 |
GO:00432446 | Esophagus | ESCC | regulation of protein-containing complex disassembly | 75/8552 | 121/18723 | 2.17e-04 | 1.36e-03 | 75 |
GO:00311104 | Esophagus | ESCC | regulation of microtubule polymerization or depolymerization | 57/8552 | 88/18723 | 2.32e-04 | 1.44e-03 | 57 |
GO:006156415 | Esophagus | ESCC | axon development | 251/8552 | 467/18723 | 2.41e-04 | 1.49e-03 | 251 |
GO:00346431 | Esophagus | ESCC | establishment of mitochondrion localization, microtubule-mediated | 21/8552 | 26/18723 | 2.69e-04 | 1.63e-03 | 21 |
GO:00474971 | Esophagus | ESCC | mitochondrion transport along microtubule | 21/8552 | 26/18723 | 2.69e-04 | 1.63e-03 | 21 |
GO:00516463 | Esophagus | ESCC | mitochondrion localization | 35/8552 | 50/18723 | 4.33e-04 | 2.44e-03 | 35 |
GO:00328864 | Esophagus | ESCC | regulation of microtubule-based process | 134/8552 | 240/18723 | 9.44e-04 | 4.80e-03 | 134 |
GO:003149811 | Esophagus | ESCC | chromatin disassembly | 16/8552 | 20/18723 | 1.85e-03 | 8.40e-03 | 16 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
MAP1S | SNV | Missense_Mutation | novel | c.2570N>G | p.Glu857Gly | p.E857G | Q66K74 | protein_coding | tolerated(0.22) | benign(0.001) | TCGA-A5-A1OF-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
MAP1S | SNV | Missense_Mutation | novel | c.1465G>A | p.Ala489Thr | p.A489T | Q66K74 | protein_coding | tolerated(0.74) | benign(0) | TCGA-AJ-A3BH-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |
MAP1S | SNV | Missense_Mutation | rs749145474 | c.1406N>A | p.Arg469Gln | p.R469Q | Q66K74 | protein_coding | deleterious(0.02) | possibly_damaging(0.865) | TCGA-AX-A2HC-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | paclitaxel | PD |
MAP1S | SNV | Missense_Mutation | novel | c.1426N>A | p.Val476Met | p.V476M | Q66K74 | protein_coding | deleterious(0.04) | possibly_damaging(0.823) | TCGA-AX-A3FT-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
MAP1S | SNV | Missense_Mutation | rs756750698 | c.2984N>T | p.Ala995Val | p.A995V | Q66K74 | protein_coding | deleterious(0) | possibly_damaging(0.712) | TCGA-AX-A3G8-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
MAP1S | SNV | Missense_Mutation | novel | c.563C>T | p.Ala188Val | p.A188V | Q66K74 | protein_coding | tolerated(0.64) | benign(0.001) | TCGA-B5-A11E-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
MAP1S | SNV | Missense_Mutation | novel | c.3067N>A | p.Trp1023Arg | p.W1023R | Q66K74 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-BG-A222-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
MAP1S | SNV | Missense_Mutation | rs763270826 | c.625G>A | p.Glu209Lys | p.E209K | Q66K74 | protein_coding | deleterious(0) | possibly_damaging(0.454) | TCGA-BS-A0UV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
MAP1S | SNV | Missense_Mutation | novel | c.2644N>A | p.Ala882Thr | p.A882T | Q66K74 | protein_coding | tolerated(0.49) | benign(0.005) | TCGA-D1-A1NS-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
MAP1S | SNV | Missense_Mutation | novel | c.748N>A | p.Leu250Ile | p.L250I | Q66K74 | protein_coding | tolerated(0.12) | possibly_damaging(0.743) | TCGA-DF-A2KU-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |