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Gene: CNIH1 |
Gene summary for CNIH1 |
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Gene information | Species | Human | Gene symbol | CNIH1 | Gene ID | 10175 |
Gene name | cornichon family AMPA receptor auxiliary protein 1 | |
Gene Alias | CNIH | |
Cytomap | 14q22.2 | |
Gene Type | protein-coding | GO ID | GO:0002376 | UniProtAcc | B2R4P1 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
10175 | CNIH1 | HTA11_347_2000001011 | Human | Colorectum | AD | 4.75e-03 | 2.51e-01 | -0.1954 |
10175 | CNIH1 | HTA11_866_3004761011 | Human | Colorectum | AD | 4.90e-04 | 3.48e-01 | 0.096 |
10175 | CNIH1 | HTA11_99999970781_79442 | Human | Colorectum | MSS | 3.48e-15 | 6.56e-01 | 0.294 |
10175 | CNIH1 | A018-E-020 | Human | Colorectum | FAP | 1.39e-03 | -1.52e-01 | -0.2034 |
10175 | CNIH1 | LZE3D | Human | Esophagus | HGIN | 3.02e-02 | 7.70e-01 | 0.0668 |
10175 | CNIH1 | LZE4T | Human | Esophagus | ESCC | 2.01e-23 | 1.10e+00 | 0.0811 |
10175 | CNIH1 | LZE7T | Human | Esophagus | ESCC | 6.22e-05 | 2.58e-01 | 0.0667 |
10175 | CNIH1 | LZE21D1 | Human | Esophagus | HGIN | 1.67e-05 | 4.48e-01 | 0.0632 |
10175 | CNIH1 | LZE24T | Human | Esophagus | ESCC | 5.62e-13 | 6.90e-01 | 0.0596 |
10175 | CNIH1 | LZE6T | Human | Esophagus | ESCC | 9.51e-03 | 7.36e-01 | 0.0845 |
10175 | CNIH1 | P2T-E | Human | Esophagus | ESCC | 1.48e-20 | 6.84e-01 | 0.1177 |
10175 | CNIH1 | P4T-E | Human | Esophagus | ESCC | 1.07e-44 | 1.59e+00 | 0.1323 |
10175 | CNIH1 | P5T-E | Human | Esophagus | ESCC | 2.10e-29 | 1.01e+00 | 0.1327 |
10175 | CNIH1 | P8T-E | Human | Esophagus | ESCC | 7.46e-43 | 1.13e+00 | 0.0889 |
10175 | CNIH1 | P9T-E | Human | Esophagus | ESCC | 3.20e-13 | 7.22e-01 | 0.1131 |
10175 | CNIH1 | P10T-E | Human | Esophagus | ESCC | 1.24e-56 | 1.30e+00 | 0.116 |
10175 | CNIH1 | P11T-E | Human | Esophagus | ESCC | 4.29e-09 | 1.01e+00 | 0.1426 |
10175 | CNIH1 | P12T-E | Human | Esophagus | ESCC | 6.97e-54 | 1.49e+00 | 0.1122 |
10175 | CNIH1 | P15T-E | Human | Esophagus | ESCC | 2.60e-65 | 2.37e+00 | 0.1149 |
10175 | CNIH1 | P16T-E | Human | Esophagus | ESCC | 8.59e-18 | 5.59e-01 | 0.1153 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CNIH1 | insertion | Frame_Shift_Ins | novel | c.394dupT | p.Tyr132LeufsTer56 | p.Y132Lfs*56 | O95406 | protein_coding | TCGA-VQ-A922-01 | Stomach | stomach adenocarcinoma | Male | >=65 | III/IV | Chemotherapy | fluorouracil | PD |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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