Tissue | Expression Dynamics | Abbreviation |
Breast | | IDC: Invasive ductal carcinoma |
DCIS: Ductal carcinoma in situ |
Precancer(BRCA1-mut): Precancerous lesion from BRCA1 mutation carriers |
Colorectum (GSE201348) | | FAP: Familial adenomatous polyposis |
CRC: Colorectal cancer |
Colorectum (HTA11) | | AD: Adenomas |
SER: Sessile serrated lesions |
MSI-H: Microsatellite-high colorectal cancer |
MSS: Microsatellite stable colorectal cancer |
Esophagus | | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias |
LGIN: Low-grade intraepithelial neoplasias |
Liver | | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000961211 | Breast | IDC | response to mechanical stimulus | 34/1434 | 216/18723 | 4.59e-05 | 1.03e-03 | 34 |
GO:000961221 | Breast | DCIS | response to mechanical stimulus | 32/1390 | 216/18723 | 1.36e-04 | 2.33e-03 | 32 |
GO:0045216 | Colorectum | AD | cell-cell junction organization | 80/3918 | 200/18723 | 5.57e-10 | 4.58e-08 | 80 |
GO:0034329 | Colorectum | AD | cell junction assembly | 136/3918 | 420/18723 | 2.02e-08 | 1.15e-06 | 136 |
GO:0007043 | Colorectum | AD | cell-cell junction assembly | 57/3918 | 146/18723 | 4.18e-07 | 1.61e-05 | 57 |
GO:1901888 | Colorectum | AD | regulation of cell junction assembly | 61/3918 | 204/18723 | 1.50e-03 | 1.27e-02 | 61 |
GO:00452161 | Colorectum | SER | cell-cell junction organization | 63/2897 | 200/18723 | 9.15e-09 | 7.80e-07 | 63 |
GO:00070431 | Colorectum | SER | cell-cell junction assembly | 45/2897 | 146/18723 | 2.23e-06 | 9.31e-05 | 45 |
GO:00343291 | Colorectum | SER | cell junction assembly | 100/2897 | 420/18723 | 4.23e-06 | 1.61e-04 | 100 |
GO:19018881 | Colorectum | SER | regulation of cell junction assembly | 46/2897 | 204/18723 | 4.70e-03 | 3.70e-02 | 46 |
GO:00452162 | Colorectum | MSS | cell-cell junction organization | 69/3467 | 200/18723 | 5.07e-08 | 2.70e-06 | 69 |
GO:00343292 | Colorectum | MSS | cell junction assembly | 120/3467 | 420/18723 | 2.51e-07 | 1.07e-05 | 120 |
GO:00070432 | Colorectum | MSS | cell-cell junction assembly | 50/3467 | 146/18723 | 4.24e-06 | 1.21e-04 | 50 |
GO:003432918 | Esophagus | ESCC | cell junction assembly | 227/8552 | 420/18723 | 3.06e-04 | 1.83e-03 | 227 |
GO:000961216 | Esophagus | ESCC | response to mechanical stimulus | 124/8552 | 216/18723 | 3.30e-04 | 1.94e-03 | 124 |
GO:004521620 | Esophagus | ESCC | cell-cell junction organization | 114/8552 | 200/18723 | 8.04e-04 | 4.16e-03 | 114 |
GO:00215436 | Esophagus | ESCC | pallium development | 94/8552 | 169/18723 | 5.79e-03 | 2.14e-02 | 94 |
GO:190188810 | Esophagus | ESCC | regulation of cell junction assembly | 109/8552 | 204/18723 | 1.53e-02 | 4.96e-02 | 109 |
GO:004521622 | Liver | HCC | cell-cell junction organization | 107/7958 | 200/18723 | 1.06e-03 | 6.11e-03 | 107 |
GO:00096124 | Liver | HCC | response to mechanical stimulus | 113/7958 | 216/18723 | 2.20e-03 | 1.10e-02 | 113 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CNTNAP2 | SNV | Missense_Mutation | rs886062050 | c.637G>A | p.Ala213Thr | p.A213T | Q9UHC6 | protein_coding | deleterious(0.04) | benign(0.003) | TCGA-85-8070-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
CNTNAP2 | SNV | Missense_Mutation | novel | c.3005N>G | p.Asn1002Ser | p.N1002S | Q9UHC6 | protein_coding | tolerated(0.96) | benign(0.001) | TCGA-85-8072-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
CNTNAP2 | SNV | Missense_Mutation | novel | c.888G>T | p.Met296Ile | p.M296I | Q9UHC6 | protein_coding | tolerated(0.06) | benign(0.003) | TCGA-85-8277-01 | Lung | lung squamous cell carcinoma | Male | >=65 | III/IV | Unknown | Unknown | SD |
CNTNAP2 | SNV | Missense_Mutation | novel | c.2324N>A | p.Thr775Asn | p.T775N | Q9UHC6 | protein_coding | deleterious(0) | possibly_damaging(0.536) | TCGA-85-8355-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
CNTNAP2 | SNV | Missense_Mutation | novel | c.1935N>T | p.Gln645His | p.Q645H | Q9UHC6 | protein_coding | deleterious(0.04) | benign(0.37) | TCGA-85-8481-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
CNTNAP2 | SNV | Missense_Mutation | | c.631G>T | p.Val211Phe | p.V211F | Q9UHC6 | protein_coding | deleterious(0.01) | possibly_damaging(0.741) | TCGA-85-8584-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
CNTNAP2 | SNV | Missense_Mutation | novel | c.3016N>C | p.Gly1006Arg | p.G1006R | Q9UHC6 | protein_coding | deleterious(0) | probably_damaging(0.974) | TCGA-85-8664-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Chemotherapy | carboplatin | PD |
CNTNAP2 | SNV | Missense_Mutation | | c.1718N>T | p.Trp573Leu | p.W573L | Q9UHC6 | protein_coding | deleterious(0) | probably_damaging(0.959) | TCGA-90-7964-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
CNTNAP2 | SNV | Missense_Mutation | novel | c.1719N>T | p.Trp573Cys | p.W573C | Q9UHC6 | protein_coding | deleterious(0) | probably_damaging(0.994) | TCGA-90-7964-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
CNTNAP2 | SNV | Missense_Mutation | novel | c.3845N>A | p.Leu1282Gln | p.L1282Q | Q9UHC6 | protein_coding | tolerated(0.05) | possibly_damaging(0.878) | TCGA-92-8063-01 | Lung | lung squamous cell carcinoma | Male | <65 | III/IV | Chemotherapy | taxol | SD |