GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:002260410 | Cervix | CC | regulation of cell morphogenesis | 84/2311 | 309/18723 | 1.00e-12 | 4.29e-10 | 84 |
GO:00160498 | Cervix | CC | cell growth | 92/2311 | 482/18723 | 1.16e-05 | 2.49e-04 | 92 |
GO:00459277 | Cervix | CC | positive regulation of growth | 53/2311 | 259/18723 | 1.33e-04 | 1.64e-03 | 53 |
GO:00015588 | Cervix | CC | regulation of cell growth | 77/2311 | 414/18723 | 1.40e-04 | 1.70e-03 | 77 |
GO:00303077 | Cervix | CC | positive regulation of cell growth | 36/2311 | 166/18723 | 4.84e-04 | 4.75e-03 | 36 |
GO:00486386 | Cervix | CC | regulation of developmental growth | 61/2311 | 330/18723 | 7.69e-04 | 6.85e-03 | 61 |
GO:00605606 | Cervix | CC | developmental growth involved in morphogenesis | 46/2311 | 234/18723 | 8.82e-04 | 7.63e-03 | 46 |
GO:00171574 | Cervix | CC | regulation of exocytosis | 39/2311 | 202/18723 | 2.90e-03 | 1.93e-02 | 39 |
GO:19901385 | Cervix | CC | neuron projection extension | 34/2311 | 172/18723 | 3.52e-03 | 2.27e-02 | 34 |
GO:00486395 | Cervix | CC | positive regulation of developmental growth | 33/2311 | 174/18723 | 7.65e-03 | 4.07e-02 | 33 |
GO:00485886 | Cervix | CC | developmental cell growth | 42/2311 | 234/18723 | 7.88e-03 | 4.15e-02 | 42 |
GO:00068873 | Cervix | CC | exocytosis | 59/2311 | 352/18723 | 8.74e-03 | 4.48e-02 | 59 |
GO:00158337 | Cervix | CC | peptide transport | 46/2311 | 264/18723 | 9.69e-03 | 4.78e-02 | 46 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
RIMS2 | SNV | Missense_Mutation | novel | c.1648N>C | p.Asp550His | p.D550H | Q9UQ26 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.495) | TCGA-BA-6869-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | III/IV | Unknown | Unknown | SD |
RIMS2 | SNV | Missense_Mutation | | c.2393G>T | p.Arg798Ile | p.R798I | Q9UQ26 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.971) | TCGA-BA-A6DA-01 | Oral cavity | head & neck squamous cell carcinoma | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
RIMS2 | SNV | Missense_Mutation | | c.1850N>T | p.Cys617Phe | p.C617F | Q9UQ26 | protein_coding | tolerated_low_confidence(0.08) | probably_damaging(0.949) | TCGA-BB-A5HY-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Chemotherapy | cisplatin | PD |
RIMS2 | SNV | Missense_Mutation | novel | c.1397N>C | p.Val466Ala | p.V466A | Q9UQ26 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.911) | TCGA-CN-4738-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
RIMS2 | SNV | Missense_Mutation | rs200234707 | c.1513N>A | p.Gly505Ser | p.G505S | Q9UQ26 | protein_coding | tolerated_low_confidence(0.05) | probably_damaging(0.981) | TCGA-CN-4741-01 | Oral cavity | head & neck squamous cell carcinoma | Male | >=65 | I/II | Chemotherapy | cisplatin | PD |
RIMS2 | SNV | Missense_Mutation | novel | c.1027C>T | p.Pro343Ser | p.P343S | Q9UQ26 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.999) | TCGA-CN-5360-01 | Oral cavity | head & neck squamous cell carcinoma | Male | >=65 | I/II | Chemotherapy | cisplatin | SD |
RIMS2 | SNV | Missense_Mutation | novel | c.3993N>C | p.Arg1331Ser | p.R1331S | Q9UQ26 | protein_coding | deleterious_low_confidence(0.01) | benign(0.23) | TCGA-CN-A498-01 | Oral cavity | head & neck squamous cell carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatin | PD |
RIMS2 | SNV | Missense_Mutation | novel | c.3592N>T | p.Asp1198Tyr | p.D1198Y | Q9UQ26 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.987) | TCGA-CN-A63U-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
RIMS2 | SNV | Missense_Mutation | | c.3508N>A | p.Asp1170Asn | p.D1170N | Q9UQ26 | protein_coding | deleterious_low_confidence(0) | benign(0.295) | TCGA-CN-A6V1-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Immunotherapy | erbitux | CR |
RIMS2 | SNV | Missense_Mutation | novel | c.2650T>C | p.Tyr884His | p.Y884H | Q9UQ26 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.785) | TCGA-CN-A6V3-01 | Oral cavity | head & neck squamous cell carcinoma | Male | <65 | I/II | Chemotherapy | cisplatin | CR |