GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00510565 | Lung | IAC | regulation of small GTPase mediated signal transduction | 70/2061 | 302/18723 | 9.44e-10 | 1.87e-07 | 70 |
GO:00458607 | Lung | IAC | positive regulation of protein kinase activity | 72/2061 | 386/18723 | 4.89e-06 | 1.96e-04 | 72 |
GO:00336748 | Lung | IAC | positive regulation of kinase activity | 83/2061 | 467/18723 | 6.76e-06 | 2.45e-04 | 83 |
GO:005105611 | Lung | AIS | regulation of small GTPase mediated signal transduction | 66/1849 | 302/18723 | 4.26e-10 | 9.53e-08 | 66 |
GO:003367412 | Lung | AIS | positive regulation of kinase activity | 77/1849 | 467/18723 | 4.67e-06 | 2.31e-04 | 77 |
GO:004586012 | Lung | AIS | positive regulation of protein kinase activity | 65/1849 | 386/18723 | 1.27e-05 | 4.78e-04 | 65 |
GO:0018212 | Lung | AIS | peptidyl-tyrosine modification | 56/1849 | 378/18723 | 1.35e-03 | 1.68e-02 | 56 |
GO:0018108 | Lung | AIS | peptidyl-tyrosine phosphorylation | 55/1849 | 375/18723 | 1.87e-03 | 2.08e-02 | 55 |
GO:0045860111 | Thyroid | PTC | positive regulation of protein kinase activity | 176/5968 | 386/18723 | 8.89e-09 | 2.17e-07 | 176 |
GO:0033674111 | Thyroid | PTC | positive regulation of kinase activity | 201/5968 | 467/18723 | 1.95e-07 | 3.54e-06 | 201 |
GO:005105617 | Thyroid | PTC | regulation of small GTPase mediated signal transduction | 132/5968 | 302/18723 | 9.26e-06 | 1.04e-04 | 132 |
GO:00610974 | Thyroid | PTC | regulation of protein tyrosine kinase activity | 45/5968 | 90/18723 | 2.57e-04 | 1.84e-03 | 45 |
GO:00182126 | Thyroid | PTC | peptidyl-tyrosine modification | 142/5968 | 378/18723 | 1.02e-02 | 4.14e-02 | 142 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5549delN | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-D1-A17H-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5549delN | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-D1-A17U-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatin | SD |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5555delC | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-D1-A1NZ-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5555delC | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-D1-A2G5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5549delN | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-DF-A2KZ-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5549delN | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-E6-A2P8-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | PD |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5549delN | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-E6-A2P9-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5549delN | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-EO-A22S-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK3 | deletion | Frame_Shift_Del | rs782665429 | c.5549delN | p.Pro1852GlnfsTer45 | p.P1852Qfs*45 | Q8IZD9 | protein_coding | | | TCGA-EO-A3AZ-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
DOCK3 | insertion | Frame_Shift_Ins | rs782552436 | c.5548_5549insC | p.Ala1853SerfsTer46 | p.A1853Sfs*46 | Q8IZD9 | protein_coding | | | TCGA-EY-A1GI-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |