GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:001603227 | Esophagus | HGIN | viral process | 118/2587 | 415/18723 | 3.01e-15 | 6.22e-13 | 118 |
GO:001905827 | Esophagus | HGIN | viral life cycle | 93/2587 | 317/18723 | 3.66e-13 | 5.63e-11 | 93 |
GO:005079225 | Esophagus | HGIN | regulation of viral process | 50/2587 | 164/18723 | 2.53e-08 | 1.49e-06 | 50 |
GO:190390025 | Esophagus | HGIN | regulation of viral life cycle | 45/2587 | 148/18723 | 1.36e-07 | 6.78e-06 | 45 |
GO:004852419 | Esophagus | HGIN | positive regulation of viral process | 25/2587 | 65/18723 | 6.88e-07 | 2.95e-05 | 25 |
GO:004440326 | Esophagus | HGIN | biological process involved in symbiotic interaction | 71/2587 | 290/18723 | 7.09e-07 | 3.00e-05 | 71 |
GO:005170127 | Esophagus | HGIN | biological process involved in interaction with host | 51/2587 | 203/18723 | 1.16e-05 | 3.29e-04 | 51 |
GO:001908016 | Esophagus | HGIN | viral gene expression | 28/2587 | 94/18723 | 4.52e-05 | 1.09e-03 | 28 |
GO:005212627 | Esophagus | HGIN | movement in host environment | 43/2587 | 175/18723 | 9.45e-05 | 2.03e-03 | 43 |
GO:190390210 | Esophagus | HGIN | positive regulation of viral life cycle | 12/2587 | 29/18723 | 2.48e-04 | 4.38e-03 | 12 |
GO:004852510 | Esophagus | HGIN | negative regulation of viral process | 25/2587 | 92/18723 | 5.41e-04 | 7.71e-03 | 25 |
GO:004390320 | Esophagus | HGIN | regulation of biological process involved in symbiotic interaction | 20/2587 | 72/18723 | 1.39e-03 | 1.63e-02 | 20 |
GO:004659815 | Esophagus | HGIN | positive regulation of viral entry into host cell | 6/2587 | 11/18723 | 1.71e-03 | 1.86e-02 | 6 |
GO:007529415 | Esophagus | HGIN | positive regulation by symbiont of entry into host | 6/2587 | 11/18723 | 1.71e-03 | 1.86e-02 | 6 |
GO:00190834 | Esophagus | HGIN | viral transcription | 15/2587 | 50/18723 | 2.35e-03 | 2.39e-02 | 15 |
GO:004440927 | Esophagus | HGIN | entry into host | 34/2587 | 151/18723 | 2.43e-03 | 2.43e-02 | 34 |
GO:000961517 | Esophagus | HGIN | response to virus | 69/2587 | 367/18723 | 4.39e-03 | 3.86e-02 | 69 |
GO:00190766 | Esophagus | HGIN | viral release from host cell | 11/2587 | 34/18723 | 4.61e-03 | 3.96e-02 | 11 |
GO:00358906 | Esophagus | HGIN | exit from host | 11/2587 | 34/18723 | 4.61e-03 | 3.96e-02 | 11 |
GO:00358916 | Esophagus | HGIN | exit from host cell | 11/2587 | 34/18723 | 4.61e-03 | 3.96e-02 | 11 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
TRIM11 | SNV | Missense_Mutation | novel | c.970C>T | p.Arg324Cys | p.R324C | Q96F44 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-AP-A1DR-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | cisplatin | SD |
TRIM11 | SNV | Missense_Mutation | rs370800532 | c.1291G>A | p.Glu431Lys | p.E431K | Q96F44 | protein_coding | deleterious(0.04) | benign(0.111) | TCGA-AP-A1E0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | paclitaxel | SD |
TRIM11 | SNV | Missense_Mutation | rs753855545 | c.1304N>T | p.Ser435Leu | p.S435L | Q96F44 | protein_coding | tolerated(0.06) | possibly_damaging(0.828) | TCGA-AX-A0J0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TRIM11 | SNV | Missense_Mutation | | c.1126N>A | p.Gly376Ser | p.G376S | Q96F44 | protein_coding | deleterious(0) | probably_damaging(0.997) | TCGA-AX-A0J1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TRIM11 | SNV | Missense_Mutation | novel | c.650A>G | p.His217Arg | p.H217R | Q96F44 | protein_coding | tolerated(0.94) | benign(0) | TCGA-AX-A2HD-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
TRIM11 | SNV | Missense_Mutation | rs752798123 | c.550N>T | p.Arg184Cys | p.R184C | Q96F44 | protein_coding | deleterious(0) | possibly_damaging(0.676) | TCGA-BG-A222-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TRIM11 | SNV | Missense_Mutation | | c.982G>T | p.Gly328Cys | p.G328C | Q96F44 | protein_coding | tolerated(0.23) | benign(0.007) | TCGA-BG-A2L7-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Chemotherapy | carboplatin | CR |
TRIM11 | SNV | Missense_Mutation | | c.1375N>T | p.Gly459Cys | p.G459C | Q96F44 | protein_coding | deleterious(0.04) | probably_damaging(0.92) | TCGA-BS-A0U7-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TRIM11 | SNV | Missense_Mutation | | c.1126N>A | p.Gly376Ser | p.G376S | Q96F44 | protein_coding | deleterious(0) | probably_damaging(0.997) | TCGA-D1-A103-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TRIM11 | SNV | Missense_Mutation | novel | c.809G>T | p.Arg270Met | p.R270M | Q96F44 | protein_coding | deleterious(0) | benign(0.438) | TCGA-DF-A2KN-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |