GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00447723 | Lung | IAC | mitotic cell cycle phase transition | 85/2061 | 424/18723 | 2.69e-08 | 3.20e-06 | 85 |
GO:00000823 | Lung | IAC | G1/S transition of mitotic cell cycle | 46/2061 | 214/18723 | 6.13e-06 | 2.29e-04 | 46 |
GO:00448433 | Lung | IAC | cell cycle G1/S phase transition | 49/2061 | 241/18723 | 1.54e-05 | 4.49e-04 | 49 |
GO:19019872 | Lung | IAC | regulation of cell cycle phase transition | 69/2061 | 390/18723 | 4.55e-05 | 1.06e-03 | 69 |
GO:00073464 | Lung | IAC | regulation of mitotic cell cycle | 78/2061 | 457/18723 | 5.37e-05 | 1.21e-03 | 78 |
GO:00457861 | Lung | IAC | negative regulation of cell cycle | 67/2061 | 385/18723 | 9.74e-05 | 1.93e-03 | 67 |
GO:00459301 | Lung | IAC | negative regulation of mitotic cell cycle | 45/2061 | 235/18723 | 1.49e-04 | 2.73e-03 | 45 |
GO:19019881 | Lung | IAC | negative regulation of cell cycle phase transition | 47/2061 | 249/18723 | 1.53e-04 | 2.80e-03 | 47 |
GO:00109481 | Lung | IAC | negative regulation of cell cycle process | 53/2061 | 294/18723 | 2.05e-04 | 3.58e-03 | 53 |
GO:19019902 | Lung | IAC | regulation of mitotic cell cycle phase transition | 53/2061 | 299/18723 | 3.14e-04 | 4.98e-03 | 53 |
GO:00448391 | Lung | IAC | cell cycle G2/M phase transition | 29/2061 | 148/18723 | 1.44e-03 | 1.55e-02 | 29 |
GO:00000861 | Lung | IAC | G2/M transition of mitotic cell cycle | 27/2061 | 137/18723 | 1.88e-03 | 1.92e-02 | 27 |
GO:19019911 | Lung | IAC | negative regulation of mitotic cell cycle phase transition | 33/2061 | 179/18723 | 2.05e-03 | 2.05e-02 | 33 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
GPR132 | SNV | Missense_Mutation | novel | c.427G>A | p.Ala143Thr | p.A143T | Q9UNW8 | protein_coding | deleterious(0) | probably_damaging(0.998) | TCGA-A5-A0G1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | novel | c.277G>T | p.Gly93Cys | p.G93C | Q9UNW8 | protein_coding | tolerated(0.14) | benign(0.045) | TCGA-A5-A1OF-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | rs142982882 | c.110C>A | p.Ser37Tyr | p.S37Y | Q9UNW8 | protein_coding | tolerated(1) | benign(0.034) | TCGA-A5-A2K5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | | c.1121N>T | p.Arg374Met | p.R374M | Q9UNW8 | protein_coding | deleterious_low_confidence(0.01) | benign(0.062) | TCGA-AP-A059-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | rs201663982 | c.382N>A | p.Val128Ile | p.V128I | Q9UNW8 | protein_coding | tolerated(1) | benign(0.007) | TCGA-AP-A059-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | | c.1072N>G | p.Thr358Ala | p.T358A | Q9UNW8 | protein_coding | tolerated_low_confidence(0.46) | benign(0) | TCGA-AX-A0J0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | novel | c.590C>T | p.Ala197Val | p.A197V | Q9UNW8 | protein_coding | deleterious(0.03) | probably_damaging(0.994) | TCGA-AX-A0J1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | rs757180457 | c.904N>A | p.Val302Met | p.V302M | Q9UNW8 | protein_coding | deleterious(0) | possibly_damaging(0.505) | TCGA-AX-A2HD-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | novel | c.1105N>T | p.Pro369Ser | p.P369S | Q9UNW8 | protein_coding | tolerated_low_confidence(0.57) | benign(0.055) | TCGA-B5-A3FA-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GPR132 | SNV | Missense_Mutation | rs759600274 | c.415N>A | p.Asp139Asn | p.D139N | Q9UNW8 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-D1-A103-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |