GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:001657010 | Thyroid | PTC | histone modification | 235/5968 | 463/18723 | 1.17e-17 | 1.15e-15 | 235 |
GO:0046700111 | Thyroid | PTC | heterocycle catabolic process | 221/5968 | 445/18723 | 2.43e-15 | 1.72e-13 | 221 |
GO:0044270111 | Thyroid | PTC | cellular nitrogen compound catabolic process | 223/5968 | 451/18723 | 3.34e-15 | 2.31e-13 | 223 |
GO:0019439111 | Thyroid | PTC | aromatic compound catabolic process | 225/5968 | 467/18723 | 8.51e-14 | 4.71e-12 | 225 |
GO:1901361111 | Thyroid | PTC | organic cyclic compound catabolic process | 231/5968 | 495/18723 | 2.55e-12 | 1.12e-10 | 231 |
GO:0001701111 | Thyroid | PTC | in utero embryonic development | 175/5968 | 367/18723 | 1.40e-10 | 4.73e-09 | 175 |
GO:003105610 | Thyroid | PTC | regulation of histone modification | 83/5968 | 152/18723 | 5.19e-09 | 1.34e-07 | 83 |
GO:000632520 | Thyroid | PTC | chromatin organization | 183/5968 | 409/18723 | 2.55e-08 | 5.70e-07 | 183 |
GO:00310585 | Thyroid | PTC | positive regulation of histone modification | 53/5968 | 92/18723 | 3.03e-07 | 5.13e-06 | 53 |
GO:00400297 | Thyroid | PTC | regulation of gene expression, epigenetic | 57/5968 | 105/18723 | 1.60e-06 | 2.25e-05 | 57 |
GO:00310626 | Thyroid | PTC | positive regulation of histone methylation | 26/5968 | 41/18723 | 3.23e-05 | 3.07e-04 | 26 |
GO:001657110 | Thyroid | PTC | histone methylation | 67/5968 | 141/18723 | 7.31e-05 | 6.31e-04 | 67 |
GO:000647910 | Thyroid | PTC | protein methylation | 82/5968 | 181/18723 | 1.01e-04 | 8.21e-04 | 82 |
GO:000821310 | Thyroid | PTC | protein alkylation | 82/5968 | 181/18723 | 1.01e-04 | 8.21e-04 | 82 |
GO:00310606 | Thyroid | PTC | regulation of histone methylation | 37/5968 | 69/18723 | 1.46e-04 | 1.13e-03 | 37 |
GO:009872710 | Thyroid | PTC | maintenance of cell number | 63/5968 | 134/18723 | 1.73e-04 | 1.32e-03 | 63 |
GO:00198279 | Thyroid | PTC | stem cell population maintenance | 61/5968 | 131/18723 | 3.01e-04 | 2.12e-03 | 61 |
GO:00322594 | Thyroid | PTC | methylation | 146/5968 | 364/18723 | 4.99e-04 | 3.26e-03 | 146 |
GO:000182513 | Thyroid | PTC | blastocyst formation | 22/5968 | 38/18723 | 8.19e-04 | 5.07e-03 | 22 |
GO:00434145 | Thyroid | PTC | macromolecule methylation | 127/5968 | 316/18723 | 1.02e-03 | 6.07e-03 | 127 |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
TET1 | ECM | Lung | AAH | GPR137C,AP001636.3,PLEKHA7, etc. | 4.29e-01 | |
TET1 | ECM | Lung | ADJ | GPR137C,AP001636.3,PLEKHA7, etc. | 3.95e-01 | |
TET1 | MYOFIB | Lung | ADJ | GPR137C,AP001636.3,PLEKHA7, etc. | 1.81e-01 | |
TET1 | FIB | Lung | ADJ | GPR137C,AP001636.3,PLEKHA7, etc. | 1.29e-02 | |
TET1 | ECM | Lung | AIS | GPR137C,AP001636.3,PLEKHA7, etc. | 4.29e-01 | |
TET1 | FIB | Lung | IAC | GPR137C,AP001636.3,PLEKHA7, etc. | 2.65e-02 | |
TET1 | MYOFIB | Lung | IAC | GPR137C,AP001636.3,PLEKHA7, etc. | 3.10e-01 | |
TET1 | ECM | Lung | MIAC | GPR137C,AP001636.3,PLEKHA7, etc. | 3.90e-01 | |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
TET1 | deletion | Frame_Shift_Del | novel | c.6001delN | p.Leu2002TrpfsTer18 | p.L2002Wfs*18 | Q8NFU7 | protein_coding | | | TCGA-BS-A0TJ-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TET1 | insertion | In_Frame_Ins | novel | c.2541_2542insGTCTTCATTTTTAGTTACATTTTCAAC | p.Ala847_Ser848insValPheIlePheSerTyrIlePheAsn | p.A847_S848insVFIFSYIFN | Q8NFU7 | protein_coding | | | TCGA-D1-A102-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TET1 | insertion | Frame_Shift_Ins | novel | c.4159_4160insTTCTTGTGGCAGAACCAAAAGTTCC | p.Thr1387IlefsTer18 | p.T1387Ifs*18 | Q8NFU7 | protein_coding | | | TCGA-D1-A102-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TET1 | insertion | Frame_Shift_Ins | novel | c.4097_4098insTTTG | p.Val1367LeufsTer7 | p.V1367Lfs*7 | Q8NFU7 | protein_coding | | | TCGA-D1-A103-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TET1 | deletion | Frame_Shift_Del | novel | c.3166delN | p.Lys1057AsnfsTer25 | p.K1057Nfs*25 | Q8NFU7 | protein_coding | | | TCGA-D1-A1NY-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Chemotherapy | carboplatin | SD |
TET1 | insertion | Frame_Shift_Ins | novel | c.57_58insA | p.Lys23GlufsTer37 | p.K23Efs*37 | Q8NFU7 | protein_coding | | | TCGA-DF-A2KY-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatin | SD |
TET1 | insertion | Frame_Shift_Ins | novel | c.57_58insA | p.Lys23GlufsTer37 | p.K23Efs*37 | Q8NFU7 | protein_coding | | | TCGA-E6-A2P9-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TET1 | deletion | Frame_Shift_Del | novel | c.3292delN | p.Val1100LeufsTer40 | p.V1100Lfs*40 | Q8NFU7 | protein_coding | | | TCGA-EY-A1H0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | taxol | SD |
TET1 | insertion | Frame_Shift_Ins | novel | c.65dupA | p.Lys23GlufsTer37 | p.K23Efs*37 | Q8NFU7 | protein_coding | | | TCGA-EY-A5W2-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TET1 | deletion | Frame_Shift_Del | | c.774delC | p.Val260LeufsTer11 | p.V260Lfs*11 | Q8NFU7 | protein_coding | | | TCGA-FI-A2F4-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |