GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0002064112 | Thyroid | PTC | epithelial cell development | 101/5968 | 220/18723 | 8.53e-06 | 9.74e-05 | 101 |
GO:000188519 | Thyroid | PTC | endothelial cell development | 37/5968 | 64/18723 | 1.62e-05 | 1.70e-04 | 37 |
GO:00301986 | Thyroid | PTC | extracellular matrix organization | 124/5968 | 301/18723 | 3.75e-04 | 2.53e-03 | 124 |
GO:00430626 | Thyroid | PTC | extracellular structure organization | 124/5968 | 302/18723 | 4.38e-04 | 2.92e-03 | 124 |
GO:0003158111 | Thyroid | PTC | endothelium development | 62/5968 | 136/18723 | 5.45e-04 | 3.48e-03 | 62 |
GO:004544619 | Thyroid | PTC | endothelial cell differentiation | 55/5968 | 118/18723 | 5.64e-04 | 3.59e-03 | 55 |
GO:00452296 | Thyroid | PTC | external encapsulating structure organization | 124/5968 | 304/18723 | 5.96e-04 | 3.79e-03 | 124 |
GO:003019812 | Thyroid | ATC | extracellular matrix organization | 152/6293 | 301/18723 | 8.63e-10 | 2.24e-08 | 152 |
GO:004306212 | Thyroid | ATC | extracellular structure organization | 152/6293 | 302/18723 | 1.17e-09 | 2.94e-08 | 152 |
GO:004522912 | Thyroid | ATC | external encapsulating structure organization | 152/6293 | 304/18723 | 2.11e-09 | 5.08e-08 | 152 |
GO:000206428 | Thyroid | ATC | epithelial cell development | 103/6293 | 220/18723 | 3.06e-05 | 2.55e-04 | 103 |
GO:000188526 | Thyroid | ATC | endothelial cell development | 36/6293 | 64/18723 | 1.62e-04 | 1.11e-03 | 36 |
GO:000315825 | Thyroid | ATC | endothelium development | 66/6293 | 136/18723 | 2.16e-04 | 1.42e-03 | 66 |
GO:004544623 | Thyroid | ATC | endothelial cell differentiation | 56/6293 | 118/18723 | 1.23e-03 | 6.44e-03 | 56 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
COL15A1 | SNV | Missense_Mutation | | c.2143G>T | p.Gly715Trp | p.G715W | P39059 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-66-2783-01 | Lung | lung squamous cell carcinoma | Male | >=65 | III/IV | Chemotherapy | cisplatin | CR |
COL15A1 | SNV | Missense_Mutation | novel | c.286N>C | p.Val96Leu | p.V96L | P39059 | protein_coding | tolerated(0.08) | benign(0) | TCGA-77-7141-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | | c.106G>T | p.Ala36Ser | p.A36S | P39059 | protein_coding | deleterious(0.04) | benign(0.038) | TCGA-77-8146-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.3986N>A | p.Pro1329His | p.P1329H | P39059 | protein_coding | deleterious(0.01) | possibly_damaging(0.753) | TCGA-77-8153-01 | Lung | lung squamous cell carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.2760N>T | p.Lys920Asn | p.K920N | P39059 | protein_coding | deleterious(0) | probably_damaging(0.998) | TCGA-77-A5GH-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.261C>A | p.Phe87Leu | p.F87L | P39059 | protein_coding | deleterious(0) | probably_damaging(0.994) | TCGA-85-8070-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.3167N>A | p.Gly1056Asp | p.G1056D | P39059 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-85-A4CL-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.2096N>A | p.Arg699Lys | p.R699K | P39059 | protein_coding | tolerated(0.23) | probably_damaging(0.989) | TCGA-90-A4ED-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | rs370574408 | c.3007N>A | p.Asp1003Asn | p.D1003N | P39059 | protein_coding | deleterious(0.04) | possibly_damaging(0.894) | TCGA-90-A4ED-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.1757N>A | p.Pro586His | p.P586H | P39059 | protein_coding | deleterious(0) | possibly_damaging(0.615) | TCGA-92-8063-01 | Lung | lung squamous cell carcinoma | Male | <65 | III/IV | Chemotherapy | taxol | SD |