GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:004308721 | Lung | MIAC | regulation of GTPase activity | 41/967 | 348/18723 | 7.39e-07 | 1.08e-04 | 41 |
GO:004354721 | Lung | MIAC | positive regulation of GTPase activity | 31/967 | 255/18723 | 8.63e-06 | 7.38e-04 | 31 |
GO:004887223 | Lung | MIAC | homeostasis of number of cells | 27/967 | 272/18723 | 9.04e-04 | 1.92e-02 | 27 |
GO:001635831 | Lung | MIAC | dendrite development | 23/967 | 243/18723 | 3.82e-03 | 4.69e-02 | 23 |
GO:004887226 | Oral cavity | EOLP | homeostasis of number of cells | 68/2218 | 272/18723 | 1.20e-09 | 8.27e-08 | 68 |
GO:190313114 | Oral cavity | EOLP | mononuclear cell differentiation | 88/2218 | 426/18723 | 1.07e-07 | 3.61e-06 | 88 |
GO:001635815 | Oral cavity | EOLP | dendrite development | 55/2218 | 243/18723 | 1.43e-06 | 3.42e-05 | 55 |
GO:003009812 | Oral cavity | EOLP | lymphocyte differentiation | 76/2218 | 374/18723 | 1.50e-06 | 3.55e-05 | 76 |
GO:006099614 | Oral cavity | EOLP | dendritic spine development | 27/2218 | 99/18723 | 2.21e-05 | 3.37e-04 | 27 |
GO:00022633 | Oral cavity | EOLP | cell activation involved in immune response | 56/2218 | 279/18723 | 4.91e-05 | 6.47e-04 | 56 |
GO:00023662 | Oral cavity | EOLP | leukocyte activation involved in immune response | 55/2218 | 275/18723 | 6.32e-05 | 7.90e-04 | 55 |
GO:004308714 | Oral cavity | EOLP | regulation of GTPase activity | 66/2218 | 348/18723 | 6.92e-05 | 8.55e-04 | 66 |
GO:00022852 | Oral cavity | EOLP | lymphocyte activation involved in immune response | 42/2218 | 194/18723 | 7.17e-05 | 8.82e-04 | 42 |
GO:00488137 | Oral cavity | EOLP | dendrite morphogenesis | 34/2218 | 146/18723 | 7.56e-05 | 9.19e-04 | 34 |
GO:00421132 | Oral cavity | EOLP | B cell activation | 61/2218 | 334/18723 | 3.68e-04 | 3.35e-03 | 61 |
GO:01060279 | Oral cavity | EOLP | neuron projection organization | 23/2218 | 93/18723 | 4.20e-04 | 3.72e-03 | 23 |
GO:00017761 | Oral cavity | EOLP | leukocyte homeostasis | 21/2218 | 87/18723 | 1.03e-03 | 7.63e-03 | 21 |
GO:00435479 | Oral cavity | EOLP | positive regulation of GTPase activity | 47/2218 | 255/18723 | 1.34e-03 | 9.33e-03 | 47 |
GO:00970618 | Oral cavity | EOLP | dendritic spine organization | 20/2218 | 84/18723 | 1.60e-03 | 1.07e-02 | 20 |
GO:004887233 | Oral cavity | NEOLP | homeostasis of number of cells | 65/2005 | 272/18723 | 3.20e-10 | 2.93e-08 | 65 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
DOCK10 | SNV | Missense_Mutation | novel | c.1901C>T | p.Ser634Leu | p.S634L | Q96BY6 | protein_coding | deleterious(0) | probably_damaging(0.996) | TCGA-DF-A2KU-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |
DOCK10 | SNV | Missense_Mutation | novel | c.4867N>G | p.Ile1623Val | p.I1623V | Q96BY6 | protein_coding | deleterious(0.01) | benign(0.228) | TCGA-DF-A2KV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK10 | SNV | Missense_Mutation | novel | c.3197T>G | p.Phe1066Cys | p.F1066C | Q96BY6 | protein_coding | deleterious(0) | possibly_damaging(0.885) | TCGA-E6-A1LX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK10 | SNV | Missense_Mutation | novel | c.506C>T | p.Ser169Leu | p.S169L | Q96BY6 | protein_coding | tolerated(0.34) | probably_damaging(0.99) | TCGA-E6-A1LX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK10 | SNV | Missense_Mutation | novel | c.1213N>A | p.Leu405Ile | p.L405I | Q96BY6 | protein_coding | tolerated(0.06) | probably_damaging(0.996) | TCGA-E6-A1M0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatin | SD |
DOCK10 | SNV | Missense_Mutation | novel | c.6286C>A | p.Leu2096Ile | p.L2096I | Q96BY6 | protein_coding | tolerated(0.06) | possibly_damaging(0.53) | TCGA-EO-A22R-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK10 | SNV | Missense_Mutation | novel | c.6064T>C | p.Ser2022Pro | p.S2022P | Q96BY6 | protein_coding | tolerated(0.11) | benign(0.334) | TCGA-EO-A22R-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK10 | SNV | Missense_Mutation | novel | c.1125T>G | p.Asp375Glu | p.D375E | Q96BY6 | protein_coding | tolerated(0.29) | benign(0) | TCGA-EO-A22R-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DOCK10 | SNV | Missense_Mutation | rs374472028 | c.4046N>T | p.Ser1349Leu | p.S1349L | Q96BY6 | protein_coding | deleterious(0) | probably_damaging(0.99) | TCGA-EO-A22U-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
DOCK10 | SNV | Missense_Mutation | rs775343177 | c.1229N>T | p.Thr410Met | p.T410M | Q96BY6 | protein_coding | deleterious(0.04) | possibly_damaging(0.847) | TCGA-EO-A22U-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |