GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0002064112 | Thyroid | PTC | epithelial cell development | 101/5968 | 220/18723 | 8.53e-06 | 9.74e-05 | 101 |
GO:000188519 | Thyroid | PTC | endothelial cell development | 37/5968 | 64/18723 | 1.62e-05 | 1.70e-04 | 37 |
GO:00301986 | Thyroid | PTC | extracellular matrix organization | 124/5968 | 301/18723 | 3.75e-04 | 2.53e-03 | 124 |
GO:00430626 | Thyroid | PTC | extracellular structure organization | 124/5968 | 302/18723 | 4.38e-04 | 2.92e-03 | 124 |
GO:0003158111 | Thyroid | PTC | endothelium development | 62/5968 | 136/18723 | 5.45e-04 | 3.48e-03 | 62 |
GO:004544619 | Thyroid | PTC | endothelial cell differentiation | 55/5968 | 118/18723 | 5.64e-04 | 3.59e-03 | 55 |
GO:00452296 | Thyroid | PTC | external encapsulating structure organization | 124/5968 | 304/18723 | 5.96e-04 | 3.79e-03 | 124 |
GO:003019812 | Thyroid | ATC | extracellular matrix organization | 152/6293 | 301/18723 | 8.63e-10 | 2.24e-08 | 152 |
GO:004306212 | Thyroid | ATC | extracellular structure organization | 152/6293 | 302/18723 | 1.17e-09 | 2.94e-08 | 152 |
GO:004522912 | Thyroid | ATC | external encapsulating structure organization | 152/6293 | 304/18723 | 2.11e-09 | 5.08e-08 | 152 |
GO:000206428 | Thyroid | ATC | epithelial cell development | 103/6293 | 220/18723 | 3.06e-05 | 2.55e-04 | 103 |
GO:000188526 | Thyroid | ATC | endothelial cell development | 36/6293 | 64/18723 | 1.62e-04 | 1.11e-03 | 36 |
GO:000315825 | Thyroid | ATC | endothelium development | 66/6293 | 136/18723 | 2.16e-04 | 1.42e-03 | 66 |
GO:004544623 | Thyroid | ATC | endothelial cell differentiation | 56/6293 | 118/18723 | 1.23e-03 | 6.44e-03 | 56 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
COL15A1 | SNV | Missense_Mutation | | c.1424N>T | p.Asp475Val | p.D475V | P39059 | protein_coding | deleterious_low_confidence(0.04) | benign(0.075) | TCGA-33-4566-01 | Lung | lung squamous cell carcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.1873N>T | p.Gly625Trp | p.G625W | P39059 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-33-4586-01 | Lung | lung squamous cell carcinoma | Male | <65 | III/IV | Unknown | Unknown | PD |
COL15A1 | SNV | Missense_Mutation | | c.3561N>A | p.Asp1187Glu | p.D1187E | P39059 | protein_coding | tolerated(0.13) | possibly_damaging(0.851) | TCGA-34-2596-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | | c.3922N>C | p.Asp1308His | p.D1308H | P39059 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-34-2600-01 | Lung | lung squamous cell carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.1205C>A | p.Pro402Gln | p.P402Q | P39059 | protein_coding | tolerated_low_confidence(0.15) | benign(0.094) | TCGA-43-A56V-01 | Lung | lung squamous cell carcinoma | Male | <65 | III/IV | Chemotherapy | carboplatin | PD |
COL15A1 | SNV | Missense_Mutation | | c.308N>T | p.Arg103Leu | p.R103L | P39059 | protein_coding | deleterious(0) | benign(0.376) | TCGA-56-8305-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.344N>G | p.Gln115Arg | p.Q115R | P39059 | protein_coding | deleterious(0.04) | possibly_damaging(0.86) | TCGA-56-A49D-01 | Lung | lung squamous cell carcinoma | Male | >=65 | III/IV | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | rs757515988 | c.1987N>A | p.Glu663Lys | p.E663K | P39059 | protein_coding | tolerated(0.28) | benign(0.03) | TCGA-56-A5DR-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.1371N>A | p.Asp457Glu | p.D457E | P39059 | protein_coding | tolerated_low_confidence(1) | benign(0) | TCGA-58-8386-01 | Lung | lung squamous cell carcinoma | Male | >=65 | III/IV | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.1937N>T | p.Gly646Val | p.G646V | P39059 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-58-8391-01 | Lung | lung squamous cell carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatin | PD |