Tissue | Expression Dynamics | Abbreviation |
Cervix | | CC: Cervix cancer |
HSIL_HPV: HPV-infected high-grade squamous intraepithelial lesions |
N_HPV: HPV-infected normal cervix |
Colorectum (GSE201348) | | FAP: Familial adenomatous polyposis |
CRC: Colorectal cancer |
Colorectum (HTA11) | | AD: Adenomas |
SER: Sessile serrated lesions |
MSI-H: Microsatellite-high colorectal cancer |
MSS: Microsatellite stable colorectal cancer |
Endometrium | | AEH: Atypical endometrial hyperplasia |
EEC: Endometrioid Cancer |
Esophagus | | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias |
LGIN: Low-grade intraepithelial neoplasias |
GC | | CAG: Chronic atrophic gastritis |
CAG with IM: Chronic atrophic gastritis with intestinal metaplasia |
CSG: Chronic superficial gastritis |
GC: Gastric cancer |
SIM: Severe intestinal metaplasia |
WIM: Wild intestinal metaplasia |
Liver | | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
Lung | | AAH: Atypical adenomatous hyperplasia |
AIS: Adenocarcinoma in situ |
IAC: Invasive lung adenocarcinoma |
MIA: Minimally invasive adenocarcinoma |
Oral Cavity | | EOLP: Erosive Oral lichen planus |
LP: leukoplakia |
NEOLP: Non-erosive oral lichen planus |
OSCC: Oral squamous cell carcinoma |
Prostate | | BPH: Benign Prostatic Hyperplasia |
Thyroid | | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis |
PTC: Papillary thyroid cancer |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:003297010 | Cervix | CC | regulation of actin filament-based process | 96/2311 | 397/18723 | 4.00e-11 | 8.54e-09 | 96 |
GO:00512359 | Cervix | CC | maintenance of location | 78/2311 | 327/18723 | 5.18e-09 | 4.92e-07 | 78 |
GO:005165110 | Cervix | CC | maintenance of location in cell | 55/2311 | 214/18723 | 6.63e-08 | 3.85e-06 | 55 |
GO:00160498 | Cervix | CC | cell growth | 92/2311 | 482/18723 | 1.16e-05 | 2.49e-04 | 92 |
GO:00181057 | Cervix | CC | peptidyl-serine phosphorylation | 63/2311 | 315/18723 | 6.65e-05 | 9.47e-04 | 63 |
GO:00182096 | Cervix | CC | peptidyl-serine modification | 66/2311 | 338/18723 | 9.58e-05 | 1.25e-03 | 66 |
GO:00015588 | Cervix | CC | regulation of cell growth | 77/2311 | 414/18723 | 1.40e-04 | 1.70e-03 | 77 |
GO:00165705 | Cervix | CC | histone modification | 84/2311 | 463/18723 | 1.70e-04 | 2.01e-03 | 84 |
GO:00106444 | Cervix | CC | cell communication by electrical coupling | 12/2311 | 32/18723 | 2.53e-04 | 2.79e-03 | 12 |
GO:00106494 | Cervix | CC | regulation of cell communication by electrical coupling | 8/2311 | 16/18723 | 2.73e-04 | 2.99e-03 | 8 |
GO:19023059 | Cervix | CC | regulation of sodium ion transmembrane transport | 19/2311 | 68/18723 | 4.21e-04 | 4.25e-03 | 19 |
GO:00324698 | Cervix | CC | endoplasmic reticulum calcium ion homeostasis | 10/2311 | 25/18723 | 4.52e-04 | 4.49e-03 | 10 |
GO:00300487 | Cervix | CC | actin filament-based movement | 29/2311 | 127/18723 | 6.91e-04 | 6.33e-03 | 29 |
GO:00310565 | Cervix | CC | regulation of histone modification | 33/2311 | 152/18723 | 7.97e-04 | 7.00e-03 | 33 |
GO:19018446 | Cervix | CC | regulation of cell communication by electrical coupling involved in cardiac conduction | 6/2311 | 11/18723 | 9.33e-04 | 7.86e-03 | 6 |
GO:001003810 | Cervix | CC | response to metal ion | 67/2311 | 373/18723 | 9.67e-04 | 8.10e-03 | 67 |
GO:00860644 | Cervix | CC | cell communication by electrical coupling involved in cardiac conduction | 9/2311 | 25/18723 | 2.09e-03 | 1.52e-02 | 9 |
GO:00515926 | Cervix | CC | response to calcium ion | 31/2311 | 149/18723 | 2.31e-03 | 1.65e-02 | 31 |
GO:00020288 | Cervix | CC | regulation of sodium ion transport | 21/2311 | 90/18723 | 2.71e-03 | 1.85e-02 | 21 |
GO:00551192 | Cervix | CC | relaxation of cardiac muscle | 7/2311 | 17/18723 | 2.72e-03 | 1.85e-02 | 7 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CAMK2D | SNV | Missense_Mutation | novel | c.709N>A | p.Glu237Lys | p.E237K | | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.998) | TCGA-5L-AAT1-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Hormone Therapy | letrozol | SD |
CAMK2D | SNV | Missense_Mutation | | c.911T>C | p.Ile304Thr | p.I304T | | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.953) | TCGA-AN-A0G0-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CAMK2D | SNV | Missense_Mutation | | c.1514N>A | p.Gly505Glu | p.G505E | | protein_coding | deleterious_low_confidence(0.03) | possibly_damaging(0.597) | TCGA-B6-A0RG-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CAMK2D | insertion | Frame_Shift_Ins | novel | c.70dupG | p.Ala24GlyfsTer30 | p.A24Gfs*30 | | protein_coding | | | TCGA-BH-A18G-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
CAMK2D | deletion | Frame_Shift_Del | novel | c.1417delN | p.Asp473MetfsTer64 | p.D473Mfs*64 | | protein_coding | | | TCGA-EW-A2FV-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | docetaxel | SD |
CAMK2D | SNV | Missense_Mutation | | c.920C>T | p.Thr307Ile | p.T307I | | protein_coding | deleterious_low_confidence(0.01) | possibly_damaging(0.675) | TCGA-AA-3663-01 | Colorectum | colon adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
CAMK2D | SNV | Missense_Mutation | | c.289N>C | p.Glu97Gln | p.E97Q | | protein_coding | deleterious_low_confidence(0.01) | probably_damaging(0.999) | TCGA-AA-A02H-01 | Colorectum | colon adenocarcinoma | Female | >=65 | III/IV | Unknown | Unknown | PD |
CAMK2D | SNV | Missense_Mutation | novel | c.1328C>G | p.Pro443Arg | p.P443R | | protein_coding | deleterious_low_confidence(0.04) | probably_damaging(0.994) | TCGA-AA-A02R-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
CAMK2D | SNV | Missense_Mutation | novel | c.1327C>T | p.Pro443Ser | p.P443S | | protein_coding | tolerated_low_confidence(0.1) | probably_damaging(0.991) | TCGA-AA-A02R-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
CAMK2D | SNV | Missense_Mutation | | c.509N>T | p.Ala170Val | p.A170V | | protein_coding | tolerated_low_confidence(0.08) | probably_damaging(0.999) | TCGA-DM-A1D7-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | GEFITINIB | GEFITINIB | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | GW441756X | GW441756X | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | TAE-684 | TAE-684 | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | SP-600125 | SP-600125 | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | LY-2090314 | LY-2090314 | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | LINIFANIB | LINIFANIB | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | ILORASERTIB | ILORASERTIB | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | SOTRASTAURIN | SOTRASTAURIN | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | PF-562271 | PF-00562271 | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | inhibitor | 249565838 | | |