Tissue | Expression Dynamics | Abbreviation |
Breast | | IDC: Invasive ductal carcinoma |
DCIS: Ductal carcinoma in situ |
Precancer(BRCA1-mut): Precancerous lesion from BRCA1 mutation carriers |
Cervix | | CC: Cervix cancer |
HSIL_HPV: HPV-infected high-grade squamous intraepithelial lesions |
N_HPV: HPV-infected normal cervix |
Colorectum (GSE201348) | | FAP: Familial adenomatous polyposis |
CRC: Colorectal cancer |
Colorectum (HTA11) | | AD: Adenomas |
SER: Sessile serrated lesions |
MSI-H: Microsatellite-high colorectal cancer |
MSS: Microsatellite stable colorectal cancer |
Endometrium | | AEH: Atypical endometrial hyperplasia |
EEC: Endometrioid Cancer |
Esophagus | | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias |
LGIN: Low-grade intraepithelial neoplasias |
GC | | CAG: Chronic atrophic gastritis |
CAG with IM: Chronic atrophic gastritis with intestinal metaplasia |
CSG: Chronic superficial gastritis |
GC: Gastric cancer |
SIM: Severe intestinal metaplasia |
WIM: Wild intestinal metaplasia |
Liver | | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
Oral Cavity | | EOLP: Erosive Oral lichen planus |
LP: leukoplakia |
NEOLP: Non-erosive oral lichen planus |
OSCC: Oral squamous cell carcinoma |
Prostate | | BPH: Benign Prostatic Hyperplasia |
Skin | | AK: Actinic keratosis |
cSCC: Cutaneous squamous cell carcinoma |
SCCIS:squamous cell carcinoma in situ |
Thyroid | | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis |
PTC: Papillary thyroid cancer |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00192161 | Stomach | SIM | regulation of lipid metabolic process | 27/708 | 331/18723 | 1.58e-04 | 3.50e-03 | 27 |
GO:003133051 | Stomach | SIM | negative regulation of cellular catabolic process | 23/708 | 262/18723 | 1.65e-04 | 3.56e-03 | 23 |
GO:00516515 | Stomach | SIM | maintenance of location in cell | 20/708 | 214/18723 | 1.88e-04 | 3.97e-03 | 20 |
GO:00462095 | Stomach | SIM | nitric oxide metabolic process | 11/708 | 81/18723 | 2.28e-04 | 4.59e-03 | 11 |
GO:00075685 | Stomach | SIM | aging | 27/708 | 339/18723 | 2.33e-04 | 4.64e-03 | 27 |
GO:20010575 | Stomach | SIM | reactive nitrogen species metabolic process | 11/708 | 82/18723 | 2.54e-04 | 4.96e-03 | 11 |
GO:00468901 | Stomach | SIM | regulation of lipid biosynthetic process | 17/708 | 171/18723 | 2.71e-04 | 5.21e-03 | 17 |
GO:00705855 | Stomach | SIM | protein localization to mitochondrion | 14/708 | 125/18723 | 2.73e-04 | 5.21e-03 | 14 |
GO:00068395 | Stomach | SIM | mitochondrial transport | 22/708 | 254/18723 | 2.74e-04 | 5.21e-03 | 22 |
GO:00712195 | Stomach | SIM | cellular response to molecule of bacterial origin | 20/708 | 221/18723 | 2.89e-04 | 5.45e-03 | 20 |
GO:20003775 | Stomach | SIM | regulation of reactive oxygen species metabolic process | 16/708 | 157/18723 | 3.07e-04 | 5.70e-03 | 16 |
GO:00106395 | Stomach | SIM | negative regulation of organelle organization | 27/708 | 348/18723 | 3.53e-04 | 6.34e-03 | 27 |
GO:00712415 | Stomach | SIM | cellular response to inorganic substance | 20/708 | 226/18723 | 3.87e-04 | 6.86e-03 | 20 |
GO:00159181 | Stomach | SIM | sterol transport | 14/708 | 130/18723 | 4.10e-04 | 7.08e-03 | 14 |
GO:00712165 | Stomach | SIM | cellular response to biotic stimulus | 21/708 | 246/18723 | 4.53e-04 | 7.60e-03 | 21 |
GO:00108234 | Stomach | SIM | negative regulation of mitochondrion organization | 8/708 | 49/18723 | 4.59e-04 | 7.62e-03 | 8 |
GO:00303011 | Stomach | SIM | cholesterol transport | 13/708 | 117/18723 | 4.82e-04 | 7.93e-03 | 13 |
GO:00454285 | Stomach | SIM | regulation of nitric oxide biosynthetic process | 9/708 | 62/18723 | 5.07e-04 | 8.19e-03 | 9 |
GO:00712485 | Stomach | SIM | cellular response to metal ion | 18/708 | 197/18723 | 5.09e-04 | 8.19e-03 | 18 |
GO:00068095 | Stomach | SIM | nitric oxide biosynthetic process | 10/708 | 76/18723 | 5.62e-04 | 8.75e-03 | 10 |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
hsa0516618 | Breast | Precancer | Human T-cell leukemia virus 1 infection | 33/684 | 222/8465 | 4.29e-04 | 3.31e-03 | 2.53e-03 | 33 |
hsa0516619 | Breast | Precancer | Human T-cell leukemia virus 1 infection | 33/684 | 222/8465 | 4.29e-04 | 3.31e-03 | 2.53e-03 | 33 |
hsa0516624 | Breast | IDC | Human T-cell leukemia virus 1 infection | 40/867 | 222/8465 | 2.52e-04 | 2.21e-03 | 1.66e-03 | 40 |
hsa0516634 | Breast | IDC | Human T-cell leukemia virus 1 infection | 40/867 | 222/8465 | 2.52e-04 | 2.21e-03 | 1.66e-03 | 40 |
hsa0516642 | Breast | DCIS | Human T-cell leukemia virus 1 infection | 41/846 | 222/8465 | 7.03e-05 | 6.88e-04 | 5.07e-04 | 41 |
hsa0516652 | Breast | DCIS | Human T-cell leukemia virus 1 infection | 41/846 | 222/8465 | 7.03e-05 | 6.88e-04 | 5.07e-04 | 41 |
hsa0516620 | Cervix | CC | Human T-cell leukemia virus 1 infection | 61/1267 | 222/8465 | 8.13e-07 | 7.98e-06 | 4.72e-06 | 61 |
hsa05166110 | Cervix | CC | Human T-cell leukemia virus 1 infection | 61/1267 | 222/8465 | 8.13e-07 | 7.98e-06 | 4.72e-06 | 61 |
hsa0516643 | Cervix | N_HPV | Human T-cell leukemia virus 1 infection | 22/349 | 222/8465 | 1.17e-04 | 1.18e-03 | 9.23e-04 | 22 |
hsa0516653 | Cervix | N_HPV | Human T-cell leukemia virus 1 infection | 22/349 | 222/8465 | 1.17e-04 | 1.18e-03 | 9.23e-04 | 22 |
hsa05166 | Colorectum | AD | Human T-cell leukemia virus 1 infection | 72/2092 | 222/8465 | 5.24e-03 | 2.44e-02 | 1.55e-02 | 72 |
hsa051661 | Colorectum | AD | Human T-cell leukemia virus 1 infection | 72/2092 | 222/8465 | 5.24e-03 | 2.44e-02 | 1.55e-02 | 72 |
hsa051662 | Colorectum | MSS | Human T-cell leukemia virus 1 infection | 68/1875 | 222/8465 | 1.84e-03 | 9.61e-03 | 5.89e-03 | 68 |
hsa051663 | Colorectum | MSS | Human T-cell leukemia virus 1 infection | 68/1875 | 222/8465 | 1.84e-03 | 9.61e-03 | 5.89e-03 | 68 |
hsa0516626 | Endometrium | AEH | Human T-cell leukemia virus 1 infection | 50/1197 | 222/8465 | 4.30e-04 | 3.11e-03 | 2.27e-03 | 50 |
hsa05166111 | Endometrium | AEH | Human T-cell leukemia virus 1 infection | 50/1197 | 222/8465 | 4.30e-04 | 3.11e-03 | 2.27e-03 | 50 |
hsa0516627 | Endometrium | EEC | Human T-cell leukemia virus 1 infection | 52/1237 | 222/8465 | 2.73e-04 | 2.36e-03 | 1.76e-03 | 52 |
hsa0516636 | Endometrium | EEC | Human T-cell leukemia virus 1 infection | 52/1237 | 222/8465 | 2.73e-04 | 2.36e-03 | 1.76e-03 | 52 |
hsa0516639 | Esophagus | HGIN | Human T-cell leukemia virus 1 infection | 51/1383 | 222/8465 | 5.84e-03 | 4.05e-02 | 3.22e-02 | 51 |
hsa05166114 | Esophagus | HGIN | Human T-cell leukemia virus 1 infection | 51/1383 | 222/8465 | 5.84e-03 | 4.05e-02 | 3.22e-02 | 51 |