GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000918514 | Cervix | N_HPV | ribonucleoside diphosphate metabolic process | 11/534 | 106/18723 | 2.21e-04 | 3.63e-03 | 11 |
GO:000925915 | Cervix | N_HPV | ribonucleotide metabolic process | 24/534 | 385/18723 | 3.08e-04 | 4.70e-03 | 24 |
GO:000989615 | Cervix | N_HPV | positive regulation of catabolic process | 28/534 | 492/18723 | 4.43e-04 | 6.10e-03 | 28 |
GO:003133115 | Cervix | N_HPV | positive regulation of cellular catabolic process | 25/534 | 427/18723 | 5.88e-04 | 7.74e-03 | 25 |
GO:00091329 | Cervix | N_HPV | nucleoside diphosphate metabolic process | 11/534 | 124/18723 | 8.50e-04 | 1.04e-02 | 11 |
GO:000911714 | Cervix | N_HPV | nucleotide metabolic process | 27/534 | 489/18723 | 8.79e-04 | 1.07e-02 | 27 |
GO:000915015 | Cervix | N_HPV | purine ribonucleotide metabolic process | 22/534 | 368/18723 | 9.40e-04 | 1.12e-02 | 22 |
GO:000675310 | Cervix | N_HPV | nucleoside phosphate metabolic process | 27/534 | 497/18723 | 1.12e-03 | 1.28e-02 | 27 |
GO:00434678 | Cervix | N_HPV | regulation of generation of precursor metabolites and energy | 11/534 | 130/18723 | 1.25e-03 | 1.39e-02 | 11 |
GO:00459815 | Cervix | N_HPV | positive regulation of nucleotide metabolic process | 6/534 | 43/18723 | 1.30e-03 | 1.42e-02 | 6 |
GO:19005445 | Cervix | N_HPV | positive regulation of purine nucleotide metabolic process | 6/534 | 43/18723 | 1.30e-03 | 1.42e-02 | 6 |
GO:00061105 | Cervix | N_HPV | regulation of glycolytic process | 6/534 | 45/18723 | 1.66e-03 | 1.71e-02 | 6 |
GO:007252115 | Cervix | N_HPV | purine-containing compound metabolic process | 23/534 | 416/18723 | 2.03e-03 | 1.98e-02 | 23 |
GO:000616315 | Cervix | N_HPV | purine nucleotide metabolic process | 22/534 | 396/18723 | 2.37e-03 | 2.18e-02 | 22 |
GO:19005425 | Cervix | N_HPV | regulation of purine nucleotide metabolic process | 8/534 | 84/18723 | 2.71e-03 | 2.38e-02 | 8 |
GO:00061404 | Cervix | N_HPV | regulation of nucleotide metabolic process | 8/534 | 86/18723 | 3.14e-03 | 2.64e-02 | 8 |
GO:00160528 | Cervix | N_HPV | carbohydrate catabolic process | 11/534 | 154/18723 | 4.72e-03 | 3.51e-02 | 11 |
GO:00434706 | Cervix | N_HPV | regulation of carbohydrate catabolic process | 6/534 | 56/18723 | 5.08e-03 | 3.73e-02 | 6 |
GO:0046034 | Colorectum | AD | ATP metabolic process | 142/3918 | 277/18723 | 2.64e-29 | 8.26e-26 | 142 |
GO:0006091 | Colorectum | AD | generation of precursor metabolites and energy | 209/3918 | 490/18723 | 3.17e-28 | 6.61e-25 | 209 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZBTB2 | SNV | Missense_Mutation | | c.764N>T | p.Ala255Val | p.A255V | Q8N680 | protein_coding | tolerated(0.98) | benign(0.07) | TCGA-A8-A06X-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZBTB2 | SNV | Missense_Mutation | | c.233N>G | p.His78Arg | p.H78R | Q8N680 | protein_coding | deleterious(0) | possibly_damaging(0.503) | TCGA-AR-A1AW-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | docetaxel | SD |
ZBTB2 | SNV | Missense_Mutation | | c.406C>G | p.Gln136Glu | p.Q136E | Q8N680 | protein_coding | deleterious(0) | possibly_damaging(0.622) | TCGA-BH-A0C0-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | carboplatin | SD |
ZBTB2 | SNV | Missense_Mutation | | c.239N>A | p.Met80Lys | p.M80K | Q8N680 | protein_coding | deleterious(0) | probably_damaging(0.977) | TCGA-D8-A1XZ-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Hormone Therapy | tamoxiphen+anastrozolum | SD |
ZBTB2 | SNV | Missense_Mutation | | c.629N>G | p.Pro210Arg | p.P210R | Q8N680 | protein_coding | tolerated(0.58) | benign(0.044) | TCGA-D8-A27G-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZBTB2 | SNV | Missense_Mutation | | c.28N>G | p.Leu10Val | p.L10V | Q8N680 | protein_coding | deleterious(0) | probably_damaging(0.981) | TCGA-EW-A1J5-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
ZBTB2 | insertion | Frame_Shift_Ins | novel | c.823_824insCGAAGGGCGATCCATTCTCCTGGGC | p.Ile275ThrfsTer18 | p.I275Tfs*18 | Q8N680 | protein_coding | | | TCGA-BH-A0AW-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | carboplatin | SD |
ZBTB2 | SNV | Missense_Mutation | | c.602N>T | p.Ser201Leu | p.S201L | Q8N680 | protein_coding | tolerated(0.22) | benign(0.144) | TCGA-EA-A439-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | PD |
ZBTB2 | SNV | Missense_Mutation | rs762417728 | c.635C>T | p.Pro212Leu | p.P212L | Q8N680 | protein_coding | tolerated(0.33) | benign(0.025) | TCGA-DM-A1HB-01 | Colorectum | colon adenocarcinoma | Male | >=65 | III/IV | Unknown | Unknown | SD |
ZBTB2 | SNV | Missense_Mutation | rs191541534 | c.340N>A | p.Ala114Thr | p.A114T | Q8N680 | protein_coding | tolerated(0.11) | benign(0.02) | TCGA-DM-A28H-01 | Colorectum | colon adenocarcinoma | Male | <65 | III/IV | Unknown | Unknown | PD |