GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00611803 | Colorectum | CRC | mammary gland epithelium development | 15/2078 | 67/18723 | 5.86e-03 | 4.33e-02 | 15 |
GO:0022407 | Colorectum | CRC | regulation of cell-cell adhesion | 67/2078 | 448/18723 | 6.86e-03 | 4.81e-02 | 67 |
GO:00071622 | Colorectum | CRC | negative regulation of cell adhesion | 48/2078 | 303/18723 | 7.14e-03 | 4.96e-02 | 48 |
GO:000641716 | Endometrium | AEH | regulation of translation | 94/2100 | 468/18723 | 1.14e-08 | 7.62e-07 | 94 |
GO:000641717 | Endometrium | EEC | regulation of translation | 94/2168 | 468/18723 | 5.37e-08 | 2.88e-06 | 94 |
GO:000641727 | Esophagus | HGIN | regulation of translation | 139/2587 | 468/18723 | 1.46e-19 | 7.98e-17 | 139 |
GO:00198277 | Esophagus | HGIN | stem cell population maintenance | 39/2587 | 131/18723 | 1.63e-06 | 6.14e-05 | 39 |
GO:00987278 | Esophagus | HGIN | maintenance of cell number | 39/2587 | 134/18723 | 3.02e-06 | 1.03e-04 | 39 |
GO:20000362 | Esophagus | HGIN | regulation of stem cell population maintenance | 11/2587 | 33/18723 | 3.55e-03 | 3.26e-02 | 11 |
GO:0006417111 | Esophagus | ESCC | regulation of translation | 304/8552 | 468/18723 | 1.53e-17 | 1.33e-15 | 304 |
GO:0048732111 | Esophagus | ESCC | gland development | 269/8552 | 436/18723 | 7.81e-12 | 2.95e-10 | 269 |
GO:001605517 | Esophagus | ESCC | Wnt signaling pathway | 268/8552 | 444/18723 | 2.32e-10 | 6.58e-09 | 268 |
GO:019873817 | Esophagus | ESCC | cell-cell signaling by wnt | 269/8552 | 446/18723 | 2.41e-10 | 6.79e-09 | 269 |
GO:00063833 | Esophagus | ESCC | transcription by RNA polymerase III | 41/8552 | 46/18723 | 7.69e-10 | 1.90e-08 | 41 |
GO:000854410 | Esophagus | ESCC | epidermis development | 193/8552 | 324/18723 | 2.87e-07 | 4.19e-06 | 193 |
GO:00715599 | Esophagus | ESCC | response to transforming growth factor beta | 157/8552 | 256/18723 | 2.95e-07 | 4.23e-06 | 157 |
GO:009872714 | Esophagus | ESCC | maintenance of cell number | 90/8552 | 134/18723 | 3.94e-07 | 5.43e-06 | 90 |
GO:001982714 | Esophagus | ESCC | stem cell population maintenance | 88/8552 | 131/18723 | 5.23e-07 | 6.97e-06 | 88 |
GO:003011117 | Esophagus | ESCC | regulation of Wnt signaling pathway | 194/8552 | 328/18723 | 5.39e-07 | 7.14e-06 | 194 |
GO:006007016 | Esophagus | ESCC | canonical Wnt signaling pathway | 180/8552 | 303/18723 | 9.15e-07 | 1.17e-05 | 180 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF7 | SNV | Missense_Mutation | novel | c.1276T>G | p.Cys426Gly | p.C426G | P17097 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-A8-A09M-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Chemotherapy | paclitaxel | CR |
ZNF7 | SNV | Missense_Mutation | rs200609680 | c.693N>C | p.Gln231His | p.Q231H | P17097 | protein_coding | deleterious(0) | benign(0.276) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
ZNF7 | SNV | Missense_Mutation | rs548449450 | c.784N>A | p.Glu262Lys | p.E262K | P17097 | protein_coding | tolerated(0.56) | benign(0.003) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF7 | SNV | Missense_Mutation | novel | c.615N>A | p.Met205Ile | p.M205I | P17097 | protein_coding | tolerated(0.24) | benign(0) | TCGA-LL-A8F5-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cyclophosphamide | SD |
ZNF7 | insertion | Nonsense_Mutation | novel | c.1045_1046insGTTTCTGATTCTGAGGTCTGGTT | p.Glu349GlyfsTer3 | p.E349Gfs*3 | P17097 | protein_coding | | | TCGA-A7-A0CE-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
ZNF7 | insertion | In_Frame_Ins | novel | c.486_487insTCTTGGCAGCTCTTCCAGCCT | p.Asn162_Cys163insSerTrpGlnLeuPheGlnPro | p.N162_C163insSWQLFQP | P17097 | protein_coding | | | TCGA-A8-A06X-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF7 | insertion | Nonsense_Mutation | novel | c.1818_1819insTCACACTGGAGAAAAACCATTTAAATGTGATGAGTGTGGCAAAGG | p.Tyr606_Leu607insSerHisTrpArgLysThrIleTerMetTerTerValTrpGlnArg | p.Y606_L607insSHWRKTI*M**VWQR | P17097 | protein_coding | | | TCGA-A8-A095-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | 5-fluorouracil | CR |
ZNF7 | insertion | Frame_Shift_Ins | novel | c.1111_1112insACAGGACTTTCCTCAGAATCCTGGCTTTGGAGACGTTTCT | p.Arg371AsnfsTer68 | p.R371Nfs*68 | P17097 | protein_coding | | | TCGA-A8-A097-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | tamoxiphen | SD |
ZNF7 | insertion | In_Frame_Ins | novel | c.435_436insAGTGAA | p.Ser145_His146insSerGlu | p.S145_H146insSE | P17097 | protein_coding | | | TCGA-B6-A0RE-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF7 | insertion | Frame_Shift_Ins | novel | c.437_438insAGGTAAAAAGTATGAAACCACT | p.His146GlnfsTer24 | p.H146Qfs*24 | P17097 | protein_coding | | | TCGA-B6-A0RE-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |