GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:004578512 | Liver | HCC | positive regulation of cell adhesion | 215/7958 | 437/18723 | 2.53e-03 | 1.22e-02 | 215 |
GO:000223711 | Liver | HCC | response to molecule of bacterial origin | 181/7958 | 363/18723 | 2.58e-03 | 1.24e-02 | 181 |
GO:00507674 | Liver | HCC | regulation of neurogenesis | 181/7958 | 364/18723 | 3.00e-03 | 1.40e-02 | 181 |
GO:000725412 | Liver | HCC | JNK cascade | 89/7958 | 167/18723 | 3.09e-03 | 1.44e-02 | 89 |
GO:00463291 | Liver | HCC | negative regulation of JNK cascade | 25/7958 | 38/18723 | 3.18e-03 | 1.47e-02 | 25 |
GO:00450881 | Liver | HCC | regulation of innate immune response | 113/7958 | 218/18723 | 3.27e-03 | 1.50e-02 | 113 |
GO:00458241 | Liver | HCC | negative regulation of innate immune response | 42/7958 | 71/18723 | 3.41e-03 | 1.55e-02 | 42 |
GO:0071901 | Liver | HCC | negative regulation of protein serine/threonine kinase activity | 66/7958 | 120/18723 | 3.81e-03 | 1.68e-02 | 66 |
GO:0050777 | Liver | HCC | negative regulation of immune response | 101/7958 | 194/18723 | 4.40e-03 | 1.90e-02 | 101 |
GO:00420631 | Liver | HCC | gliogenesis | 148/7958 | 301/18723 | 1.10e-02 | 4.07e-02 | 148 |
GO:000166721 | Liver | HCC | ameboidal-type cell migration | 226/7958 | 475/18723 | 1.35e-02 | 4.81e-02 | 226 |
GO:0043407 | Liver | HCC | negative regulation of MAP kinase activity | 34/7958 | 59/18723 | 1.36e-02 | 4.84e-02 | 34 |
GO:005134820 | Oral cavity | OSCC | negative regulation of transferase activity | 165/7305 | 268/18723 | 5.02e-14 | 2.74e-12 | 165 |
GO:001056320 | Oral cavity | OSCC | negative regulation of phosphorus metabolic process | 246/7305 | 442/18723 | 6.12e-13 | 2.89e-11 | 246 |
GO:004593620 | Oral cavity | OSCC | negative regulation of phosphate metabolic process | 245/7305 | 441/18723 | 8.85e-13 | 4.09e-11 | 245 |
GO:004232619 | Oral cavity | OSCC | negative regulation of phosphorylation | 214/7305 | 385/18723 | 2.30e-11 | 7.74e-10 | 214 |
GO:007190010 | Oral cavity | OSCC | regulation of protein serine/threonine kinase activity | 201/7305 | 359/18723 | 3.90e-11 | 1.27e-09 | 201 |
GO:000647015 | Oral cavity | OSCC | protein dephosphorylation | 162/7305 | 281/18723 | 1.56e-10 | 4.56e-09 | 162 |
GO:000193319 | Oral cavity | OSCC | negative regulation of protein phosphorylation | 191/7305 | 342/18723 | 1.58e-10 | 4.62e-09 | 191 |
GO:003367317 | Oral cavity | OSCC | negative regulation of kinase activity | 140/7305 | 237/18723 | 2.74e-10 | 7.57e-09 | 140 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
DUSP10 | SNV | Missense_Mutation | | c.20N>T | p.Asp7Val | p.D7V | Q9Y6W6 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.99) | TCGA-A8-A09Z-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
DUSP10 | SNV | Missense_Mutation | novel | c.1216A>T | p.Ile406Phe | p.I406F | Q9Y6W6 | protein_coding | deleterious(0) | probably_damaging(0.966) | TCGA-AC-A3W5-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | docetaxel | CR |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497N>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-AO-A1KT-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | fluorouracil | SD |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497N>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-B6-A0IB-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | PD |
DUSP10 | SNV | Missense_Mutation | | c.1001N>G | p.Glu334Gly | p.E334G | Q9Y6W6 | protein_coding | tolerated(0.08) | benign(0.023) | TCGA-BH-A0HA-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497A>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-BH-A0HO-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cyclophosphamide | SD |
DUSP10 | SNV | Missense_Mutation | rs747708016 | c.722N>G | p.Asn241Ser | p.N241S | Q9Y6W6 | protein_coding | tolerated(0.76) | benign(0) | TCGA-C8-A1HI-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497N>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-C8-A273-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
DUSP10 | SNV | Missense_Mutation | | c.1369N>C | p.Glu457Gln | p.E457Q | Q9Y6W6 | protein_coding | deleterious(0.01) | probably_damaging(0.937) | TCGA-D8-A1JA-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | adriamycin | PD |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497A>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-D8-A1JT-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |