GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:005123511 | Liver | Cirrhotic | maintenance of location | 117/4634 | 327/18723 | 4.78e-06 | 7.86e-05 | 117 |
GO:000726511 | Liver | Cirrhotic | Ras protein signal transduction | 119/4634 | 337/18723 | 8.16e-06 | 1.22e-04 | 119 |
GO:00224065 | Liver | Cirrhotic | membrane docking | 39/4634 | 86/18723 | 2.47e-05 | 3.22e-04 | 39 |
GO:0000045 | Liver | Cirrhotic | autophagosome assembly | 43/4634 | 99/18723 | 3.56e-05 | 4.32e-04 | 43 |
GO:00987547 | Liver | Cirrhotic | detoxification | 60/4634 | 152/18723 | 4.09e-05 | 4.86e-04 | 60 |
GO:001050811 | Liver | Cirrhotic | positive regulation of autophagy | 51/4634 | 124/18723 | 4.25e-05 | 5.03e-04 | 51 |
GO:00511006 | Liver | Cirrhotic | negative regulation of binding | 63/4634 | 162/18723 | 4.54e-05 | 5.31e-04 | 63 |
GO:1905037 | Liver | Cirrhotic | autophagosome organization | 44/4634 | 103/18723 | 4.74e-05 | 5.50e-04 | 44 |
GO:00972377 | Liver | Cirrhotic | cellular response to toxic substance | 50/4634 | 124/18723 | 9.20e-05 | 9.79e-04 | 50 |
GO:00320914 | Liver | Cirrhotic | negative regulation of protein binding | 40/4634 | 94/18723 | 1.14e-04 | 1.14e-03 | 40 |
GO:0044088 | Liver | Cirrhotic | regulation of vacuole organization | 23/4634 | 45/18723 | 1.23e-04 | 1.22e-03 | 23 |
GO:19907487 | Liver | Cirrhotic | cellular detoxification | 47/4634 | 116/18723 | 1.28e-04 | 1.26e-03 | 47 |
GO:000726611 | Liver | Cirrhotic | Rho protein signal transduction | 53/4634 | 137/18723 | 2.05e-04 | 1.89e-03 | 53 |
GO:00516517 | Liver | Cirrhotic | maintenance of location in cell | 76/4634 | 214/18723 | 2.66e-04 | 2.37e-03 | 76 |
GO:1902115 | Liver | Cirrhotic | regulation of organelle assembly | 66/4634 | 186/18723 | 6.66e-04 | 5.04e-03 | 66 |
GO:01400565 | Liver | Cirrhotic | organelle localization by membrane tethering | 32/4634 | 77/18723 | 8.65e-04 | 6.23e-03 | 32 |
GO:0031503 | Liver | Cirrhotic | protein-containing complex localization | 75/4634 | 220/18723 | 1.13e-03 | 7.73e-03 | 75 |
GO:00108223 | Liver | Cirrhotic | positive regulation of mitochondrion organization | 30/4634 | 74/18723 | 1.97e-03 | 1.23e-02 | 30 |
GO:00988697 | Liver | Cirrhotic | cellular oxidant detoxification | 38/4634 | 101/18723 | 2.72e-03 | 1.59e-02 | 38 |
GO:2000785 | Liver | Cirrhotic | regulation of autophagosome assembly | 18/4634 | 39/18723 | 2.93e-03 | 1.67e-02 | 18 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ALB | SNV | Missense_Mutation | novel | c.247N>A | p.Ala83Thr | p.A83T | P02768 | protein_coding | tolerated(0.06) | benign(0.068) | TCGA-BH-A0HF-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |
ALB | SNV | Missense_Mutation | novel | c.1814N>T | p.Ala605Val | p.A605V | P02768 | protein_coding | deleterious(0.02) | benign(0.041) | TCGA-BH-A0HF-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |
ALB | SNV | Missense_Mutation | | c.29N>A | p.Leu10His | p.L10H | P02768 | protein_coding | deleterious(0) | possibly_damaging(0.867) | TCGA-D8-A1XQ-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ALB | SNV | Missense_Mutation | | c.1802N>T | p.Ala601Val | p.A601V | P02768 | protein_coding | tolerated(0.53) | benign(0) | TCGA-D8-A1XQ-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ALB | insertion | Nonsense_Mutation | novel | c.75_76insTCTACTTATTGAAAGAGAGAAAGGAAAAAAATATGAAACAG | p.Ala26SerfsTer4 | p.A26Sfs*4 | P02768 | protein_coding | | | TCGA-A2-A0EO-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
ALB | insertion | Nonsense_Mutation | novel | c.806_807insAGCATGGAGTAACTCCATAGGCCAACA | p.Cys269delinsTer | p.C269delins* | P02768 | protein_coding | | | TCGA-BH-A0BM-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
ALB | SNV | Missense_Mutation | | c.1249N>A | p.Glu417Lys | p.E417K | P02768 | protein_coding | deleterious(0.01) | possibly_damaging(0.476) | TCGA-EK-A3GK-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
ALB | SNV | Missense_Mutation | rs267600248 | c.628C>T | p.Arg210Trp | p.R210W | P02768 | protein_coding | deleterious(0.01) | possibly_damaging(0.883) | TCGA-A6-5665-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
ALB | SNV | Missense_Mutation | rs774294755 | c.881N>T | p.Ser294Leu | p.S294L | P02768 | protein_coding | tolerated(0.31) | benign(0.041) | TCGA-AA-A00N-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |
ALB | SNV | Missense_Mutation | rs150388973 | c.946N>A | p.Glu316Lys | p.E316K | P02768 | protein_coding | tolerated(0.07) | benign(0.109) | TCGA-AZ-4313-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Sodium lauryl sulfate | | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Gadofosveset | GADOFOSVESET | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | RALTITREXED | RALTITREXED | 15025739 |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Activated recombinant FVII-albumin fusion protein | | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Oxyphenbutazone | OXYPHENBUTAZONE | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | EPIGALOCATECHIN GALLATE | EPIGALOCATECHIN GALLATE | 20598557 |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | PHENYLBUTAZONE | PHENYLBUTAZONE | 20869876 |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | EPIGALLOCATECHIN | EPIGALLOCATECHIN | 20598557 |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Iodipamide | IODIPAMIDE | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | [19F]-HALOPERIDOL | [19F]-HALOPERIDOL | |