GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:20007374 | Oral cavity | OSCC | negative regulation of stem cell differentiation | 15/7305 | 23/18723 | 9.84e-03 | 3.46e-02 | 15 |
GO:00022445 | Oral cavity | OSCC | hematopoietic progenitor cell differentiation | 57/7305 | 114/18723 | 1.09e-02 | 3.71e-02 | 57 |
GO:00488637 | Oral cavity | OSCC | stem cell differentiation | 96/7305 | 206/18723 | 1.55e-02 | 4.99e-02 | 96 |
GO:000170123 | Oral cavity | EOLP | in utero embryonic development | 72/2218 | 367/18723 | 1.02e-05 | 1.83e-04 | 72 |
GO:000170132 | Oral cavity | NEOLP | in utero embryonic development | 76/2005 | 367/18723 | 1.11e-08 | 5.44e-07 | 76 |
GO:200073713 | Oral cavity | NEOLP | negative regulation of stem cell differentiation | 10/2005 | 23/18723 | 5.95e-05 | 7.97e-04 | 10 |
GO:200073621 | Oral cavity | NEOLP | regulation of stem cell differentiation | 17/2005 | 58/18723 | 8.04e-05 | 1.01e-03 | 17 |
GO:004886316 | Oral cavity | NEOLP | stem cell differentiation | 38/2005 | 206/18723 | 5.82e-04 | 5.05e-03 | 38 |
GO:000224412 | Oral cavity | NEOLP | hematopoietic progenitor cell differentiation | 24/2005 | 114/18723 | 8.82e-04 | 6.94e-03 | 24 |
GO:19015323 | Oral cavity | NEOLP | regulation of hematopoietic progenitor cell differentiation | 10/2005 | 32/18723 | 1.36e-03 | 9.75e-03 | 10 |
GO:19020363 | Oral cavity | NEOLP | regulation of hematopoietic stem cell differentiation | 6/2005 | 14/18723 | 2.10e-03 | 1.38e-02 | 6 |
GO:00602184 | Oral cavity | NEOLP | hematopoietic stem cell differentiation | 9/2005 | 30/18723 | 3.21e-03 | 1.92e-02 | 9 |
GO:000170110 | Prostate | BPH | in utero embryonic development | 104/3107 | 367/18723 | 9.17e-09 | 3.10e-07 | 104 |
GO:19015322 | Prostate | BPH | regulation of hematopoietic progenitor cell differentiation | 15/3107 | 32/18723 | 6.38e-05 | 6.36e-04 | 15 |
GO:20007373 | Prostate | BPH | negative regulation of stem cell differentiation | 12/3107 | 23/18723 | 9.46e-05 | 8.88e-04 | 12 |
GO:00488636 | Prostate | BPH | stem cell differentiation | 55/3107 | 206/18723 | 1.56e-04 | 1.36e-03 | 55 |
GO:20007363 | Prostate | BPH | regulation of stem cell differentiation | 21/3107 | 58/18723 | 2.44e-04 | 1.94e-03 | 21 |
GO:00022444 | Prostate | BPH | hematopoietic progenitor cell differentiation | 34/3107 | 114/18723 | 3.08e-04 | 2.37e-03 | 34 |
GO:19020362 | Prostate | BPH | regulation of hematopoietic stem cell differentiation | 8/3107 | 14/18723 | 6.63e-04 | 4.46e-03 | 8 |
GO:00602183 | Prostate | BPH | hematopoietic stem cell differentiation | 12/3107 | 30/18723 | 1.94e-03 | 1.10e-02 | 12 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
N4BP2 | SNV | Missense_Mutation | | c.4384N>G | p.Gln1462Glu | p.Q1462E | Q86UW6 | protein_coding | deleterious(0.03) | benign(0.03) | TCGA-A2-A0EY-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
N4BP2 | SNV | Missense_Mutation | rs201204950 | c.4933C>T | p.Arg1645Trp | p.R1645W | Q86UW6 | protein_coding | deleterious(0) | probably_damaging(0.916) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.935N>T | p.Thr312Ile | p.T312I | Q86UW6 | protein_coding | tolerated(0.33) | benign(0.001) | TCGA-AN-A0FZ-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.4277C>T | p.Ser1426Phe | p.S1426F | Q86UW6 | protein_coding | deleterious(0) | probably_damaging(0.994) | TCGA-AR-A0TX-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.4859N>T | p.Asp1620Val | p.D1620V | Q86UW6 | protein_coding | deleterious(0) | probably_damaging(0.952) | TCGA-BH-A203-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
N4BP2 | SNV | Missense_Mutation | | c.2320N>C | p.Ser774Pro | p.S774P | Q86UW6 | protein_coding | deleterious(0.03) | benign(0.023) | TCGA-C8-A1HK-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.3085N>C | p.Glu1029Gln | p.E1029Q | Q86UW6 | protein_coding | deleterious(0) | probably_damaging(0.968) | TCGA-C8-A8HQ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
N4BP2 | SNV | Missense_Mutation | | c.2156N>A | p.Ser719Tyr | p.S719Y | Q86UW6 | protein_coding | tolerated(0.12) | benign(0.086) | TCGA-D8-A1JG-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | doxorubicin | SD |
N4BP2 | SNV | Missense_Mutation | | c.1880N>C | p.Leu627Ser | p.L627S | Q86UW6 | protein_coding | tolerated(0.16) | benign(0) | TCGA-D8-A1XK-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | doxorubicine+cyclophosphamide | SD |
N4BP2 | SNV | Missense_Mutation | novel | c.70G>A | p.Val24Ile | p.V24I | Q86UW6 | protein_coding | deleterious(0.01) | benign(0.041) | TCGA-2W-A8YY-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |