GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:007133111 | Stomach | CAG with IM | cellular response to hexose stimulus | 21/1050 | 153/18723 | 1.30e-04 | 2.68e-03 | 21 |
GO:003350011 | Stomach | CAG with IM | carbohydrate homeostasis | 30/1050 | 259/18723 | 1.35e-04 | 2.76e-03 | 30 |
GO:007132611 | Stomach | CAG with IM | cellular response to monosaccharide stimulus | 21/1050 | 154/18723 | 1.43e-04 | 2.87e-03 | 21 |
GO:007169211 | Stomach | CAG with IM | protein localization to extracellular region | 38/1050 | 368/18723 | 2.15e-04 | 3.94e-03 | 38 |
GO:190495111 | Stomach | CAG with IM | positive regulation of establishment of protein localization | 34/1050 | 319/18723 | 2.52e-04 | 4.48e-03 | 34 |
GO:000930611 | Stomach | CAG with IM | protein secretion | 37/1050 | 359/18723 | 2.69e-04 | 4.73e-03 | 37 |
GO:003559211 | Stomach | CAG with IM | establishment of protein localization to extracellular region | 37/1050 | 360/18723 | 2.84e-04 | 4.96e-03 | 37 |
GO:007132211 | Stomach | CAG with IM | cellular response to carbohydrate stimulus | 21/1050 | 163/18723 | 3.17e-04 | 5.32e-03 | 21 |
GO:005067811 | Stomach | CAG with IM | regulation of epithelial cell proliferation | 38/1050 | 381/18723 | 4.28e-04 | 6.74e-03 | 38 |
GO:005070811 | Stomach | CAG with IM | regulation of protein secretion | 29/1050 | 268/18723 | 5.45e-04 | 8.12e-03 | 29 |
GO:005071411 | Stomach | CAG with IM | positive regulation of protein secretion | 18/1050 | 137/18723 | 6.54e-04 | 9.14e-03 | 18 |
GO:000167811 | Stomach | CAG with IM | cellular glucose homeostasis | 21/1050 | 172/18723 | 6.55e-04 | 9.14e-03 | 21 |
GO:00326121 | Stomach | CAG with IM | interleukin-1 production | 17/1050 | 128/18723 | 8.07e-04 | 1.08e-02 | 17 |
GO:00326521 | Stomach | CAG with IM | regulation of interleukin-1 production | 17/1050 | 128/18723 | 8.07e-04 | 1.08e-02 | 17 |
GO:005122211 | Stomach | CAG with IM | positive regulation of protein transport | 31/1050 | 303/18723 | 9.21e-04 | 1.19e-02 | 31 |
GO:004343411 | Stomach | CAG with IM | response to peptide hormone | 39/1050 | 414/18723 | 1.09e-03 | 1.33e-02 | 39 |
GO:00326401 | Stomach | CAG with IM | tumor necrosis factor production | 21/1050 | 181/18723 | 1.27e-03 | 1.52e-02 | 21 |
GO:00326801 | Stomach | CAG with IM | regulation of tumor necrosis factor production | 21/1050 | 181/18723 | 1.27e-03 | 1.52e-02 | 21 |
GO:005067311 | Stomach | CAG with IM | epithelial cell proliferation | 40/1050 | 437/18723 | 1.62e-03 | 1.78e-02 | 40 |
GO:00717061 | Stomach | CAG with IM | tumor necrosis factor superfamily cytokine production | 21/1050 | 186/18723 | 1.79e-03 | 1.92e-02 | 21 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
GHRL | SNV | Missense_Mutation | | c.196N>A | p.Glu66Lys | p.E66K | Q9UBU3 | protein_coding | tolerated(0.12) | possibly_damaging(0.492) | TCGA-A8-A06Q-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | rs767976379 | c.187N>A | p.Gly63Ser | p.G63S | Q9UBU3 | protein_coding | tolerated(0.8) | benign(0.029) | TCGA-BH-A0EB-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |
GHRL | SNV | Missense_Mutation | rs540101934 | c.40N>A | p.Gly14Ser | p.G14S | Q9UBU3 | protein_coding | tolerated(1) | benign(0) | TCGA-G4-6628-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | novel | c.122N>T | p.Ser41Leu | p.S41L | Q9UBU3 | protein_coding | tolerated(0.19) | possibly_damaging(0.448) | TCGA-A5-A2K5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | novel | c.337G>T | p.Ala113Ser | p.A113S | Q9UBU3 | protein_coding | tolerated(0.23) | benign(0.272) | TCGA-AP-A1E1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | novel | c.290N>T | p.Ala97Val | p.A97V | Q9UBU3 | protein_coding | tolerated(0.29) | possibly_damaging(0.809) | TCGA-AX-A1CE-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unspecific | Paclitaxel | SD |
GHRL | SNV | Missense_Mutation | rs567867101 | c.173G>A | p.Arg58His | p.R58H | Q9UBU3 | protein_coding | tolerated(0.28) | benign(0) | TCGA-EO-A3KX-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | novel | c.122C>T | p.Ser41Leu | p.S41L | Q9UBU3 | protein_coding | tolerated(0.19) | possibly_damaging(0.448) | TCGA-FI-A2D4-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | carboplatinum | PD |
GHRL | SNV | Missense_Mutation | rs372434370 | c.208N>T | p.Asp70Tyr | p.D70Y | Q9UBU3 | protein_coding | deleterious(0) | possibly_damaging(0.905) | TCGA-PG-A915-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
GHRL | SNV | Missense_Mutation | rs756969269 | c.178G>A | p.Glu60Lys | p.E60K | Q9UBU3 | protein_coding | tolerated(0.05) | possibly_damaging(0.689) | TCGA-90-A4ED-01 | Lung | lung squamous cell carcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |