GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00140131 | Esophagus | ESCC | regulation of gliogenesis | 59/8552 | 103/18723 | 1.17e-02 | 3.91e-02 | 59 |
GO:00434074 | Esophagus | ESCC | negative regulation of MAP kinase activity | 36/8552 | 59/18723 | 1.27e-02 | 4.21e-02 | 36 |
GO:190303717 | Esophagus | ESCC | regulation of leukocyte cell-cell adhesion | 174/8552 | 336/18723 | 1.36e-02 | 4.43e-02 | 174 |
GO:00300984 | Esophagus | ESCC | lymphocyte differentiation | 192/8552 | 374/18723 | 1.52e-02 | 4.93e-02 | 192 |
GO:004593612 | Liver | Cirrhotic | negative regulation of phosphate metabolic process | 154/4634 | 441/18723 | 8.78e-07 | 1.83e-05 | 154 |
GO:001056312 | Liver | Cirrhotic | negative regulation of phosphorus metabolic process | 154/4634 | 442/18723 | 1.02e-06 | 2.11e-05 | 154 |
GO:004232612 | Liver | Cirrhotic | negative regulation of phosphorylation | 135/4634 | 385/18723 | 3.17e-06 | 5.58e-05 | 135 |
GO:000193312 | Liver | Cirrhotic | negative regulation of protein phosphorylation | 117/4634 | 342/18723 | 4.84e-05 | 5.59e-04 | 117 |
GO:005134812 | Liver | Cirrhotic | negative regulation of transferase activity | 93/4634 | 268/18723 | 1.55e-04 | 1.47e-03 | 93 |
GO:00457857 | Liver | Cirrhotic | positive regulation of cell adhesion | 141/4634 | 437/18723 | 2.05e-04 | 1.89e-03 | 141 |
GO:000647011 | Liver | Cirrhotic | protein dephosphorylation | 96/4634 | 281/18723 | 2.32e-04 | 2.11e-03 | 96 |
GO:003109911 | Liver | Cirrhotic | regeneration | 71/4634 | 198/18723 | 3.02e-04 | 2.65e-03 | 71 |
GO:00324966 | Liver | Cirrhotic | response to lipopolysaccharide | 111/4634 | 343/18723 | 8.15e-04 | 5.95e-03 | 111 |
GO:003109812 | Liver | Cirrhotic | stress-activated protein kinase signaling cascade | 83/4634 | 247/18723 | 1.04e-03 | 7.28e-03 | 83 |
GO:0042063 | Liver | Cirrhotic | gliogenesis | 98/4634 | 301/18723 | 1.28e-03 | 8.60e-03 | 98 |
GO:005140312 | Liver | Cirrhotic | stress-activated MAPK cascade | 80/4634 | 239/18723 | 1.43e-03 | 9.54e-03 | 80 |
GO:0002832 | Liver | Cirrhotic | negative regulation of response to biotic stimulus | 41/4634 | 108/18723 | 1.56e-03 | 1.01e-02 | 41 |
GO:001631111 | Liver | Cirrhotic | dephosphorylation | 130/4634 | 417/18723 | 1.58e-03 | 1.03e-02 | 130 |
GO:000166712 | Liver | Cirrhotic | ameboidal-type cell migration | 145/4634 | 475/18723 | 2.23e-03 | 1.36e-02 | 145 |
GO:0010001 | Liver | Cirrhotic | glial cell differentiation | 75/4634 | 225/18723 | 2.24e-03 | 1.36e-02 | 75 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
DUSP10 | SNV | Missense_Mutation | | c.20N>T | p.Asp7Val | p.D7V | Q9Y6W6 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.99) | TCGA-A8-A09Z-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
DUSP10 | SNV | Missense_Mutation | novel | c.1216A>T | p.Ile406Phe | p.I406F | Q9Y6W6 | protein_coding | deleterious(0) | probably_damaging(0.966) | TCGA-AC-A3W5-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | docetaxel | CR |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497N>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-AO-A1KT-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | fluorouracil | SD |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497N>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-B6-A0IB-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | PD |
DUSP10 | SNV | Missense_Mutation | | c.1001N>G | p.Glu334Gly | p.E334G | Q9Y6W6 | protein_coding | tolerated(0.08) | benign(0.023) | TCGA-BH-A0HA-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497A>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-BH-A0HO-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cyclophosphamide | SD |
DUSP10 | SNV | Missense_Mutation | rs747708016 | c.722N>G | p.Asn241Ser | p.N241S | Q9Y6W6 | protein_coding | tolerated(0.76) | benign(0) | TCGA-C8-A1HI-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497N>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-C8-A273-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
DUSP10 | SNV | Missense_Mutation | | c.1369N>C | p.Glu457Gln | p.E457Q | Q9Y6W6 | protein_coding | deleterious(0.01) | probably_damaging(0.937) | TCGA-D8-A1JA-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | adriamycin | PD |
DUSP10 | SNV | Missense_Mutation | rs765000706 | c.497A>C | p.His166Pro | p.H166P | Q9Y6W6 | protein_coding | deleterious(0.02) | benign(0.026) | TCGA-D8-A1JT-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |