GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00507083 | Colorectum | FAP | regulation of protein secretion | 66/2622 | 268/18723 | 2.21e-06 | 8.87e-05 | 66 |
GO:00093063 | Colorectum | FAP | protein secretion | 79/2622 | 359/18723 | 2.24e-05 | 5.31e-04 | 79 |
GO:00355923 | Colorectum | FAP | establishment of protein localization to extracellular region | 79/2622 | 360/18723 | 2.48e-05 | 5.77e-04 | 79 |
GO:00716923 | Colorectum | FAP | protein localization to extracellular region | 79/2622 | 368/18723 | 5.50e-05 | 1.10e-03 | 79 |
GO:00507963 | Colorectum | FAP | regulation of insulin secretion | 42/2622 | 165/18723 | 6.52e-05 | 1.25e-03 | 42 |
GO:0023061 | Colorectum | FAP | signal release | 94/2622 | 463/18723 | 1.06e-04 | 1.76e-03 | 94 |
GO:00510473 | Colorectum | FAP | positive regulation of secretion | 67/2622 | 310/18723 | 1.59e-04 | 2.43e-03 | 67 |
GO:19035322 | Colorectum | FAP | positive regulation of secretion by cell | 62/2622 | 282/18723 | 1.67e-04 | 2.52e-03 | 62 |
GO:00300733 | Colorectum | FAP | insulin secretion | 46/2622 | 195/18723 | 2.12e-04 | 3.03e-03 | 46 |
GO:00158333 | Colorectum | FAP | peptide transport | 58/2622 | 264/18723 | 2.71e-04 | 3.64e-03 | 58 |
GO:00902763 | Colorectum | FAP | regulation of peptide hormone secretion | 45/2622 | 196/18723 | 4.66e-04 | 5.41e-03 | 45 |
GO:00900873 | Colorectum | FAP | regulation of peptide transport | 46/2622 | 202/18723 | 4.91e-04 | 5.66e-03 | 46 |
GO:00507142 | Colorectum | FAP | positive regulation of protein secretion | 34/2622 | 137/18723 | 5.11e-04 | 5.82e-03 | 34 |
GO:00027913 | Colorectum | FAP | regulation of peptide secretion | 45/2622 | 200/18723 | 7.36e-04 | 7.83e-03 | 45 |
GO:00300722 | Colorectum | FAP | peptide hormone secretion | 51/2622 | 236/18723 | 9.09e-04 | 9.19e-03 | 51 |
GO:00428862 | Colorectum | FAP | amide transport | 62/2622 | 301/18723 | 1.01e-03 | 9.93e-03 | 62 |
GO:00027902 | Colorectum | FAP | peptide secretion | 51/2622 | 242/18723 | 1.62e-03 | 1.43e-02 | 51 |
GO:00320243 | Colorectum | FAP | positive regulation of insulin secretion | 21/2622 | 78/18723 | 1.96e-03 | 1.65e-02 | 21 |
GO:0046883 | Colorectum | FAP | regulation of hormone secretion | 50/2622 | 249/18723 | 4.97e-03 | 3.32e-02 | 50 |
GO:0046879 | Colorectum | FAP | hormone secretion | 57/2622 | 295/18723 | 6.67e-03 | 4.12e-02 | 57 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
MYRIP | SNV | Missense_Mutation | | c.1949N>C | p.Leu650Pro | p.L650P | Q8NFW9 | protein_coding | deleterious(0) | probably_damaging(0.977) | TCGA-A2-A0CP-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cytoxan | SD |
MYRIP | SNV | Missense_Mutation | | c.1665N>C | p.Gln555His | p.Q555H | Q8NFW9 | protein_coding | deleterious(0) | probably_damaging(0.991) | TCGA-AN-A0AJ-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
MYRIP | SNV | Missense_Mutation | | c.2361N>T | p.Arg787Ser | p.R787S | Q8NFW9 | protein_coding | tolerated(0.36) | benign(0.396) | TCGA-AN-A0XW-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
MYRIP | SNV | Missense_Mutation | | c.2263A>G | p.Ile755Val | p.I755V | Q8NFW9 | protein_coding | tolerated(0.34) | possibly_damaging(0.536) | TCGA-BH-A0BG-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
MYRIP | SNV | Missense_Mutation | | c.348N>T | p.Gln116His | p.Q116H | Q8NFW9 | protein_coding | deleterious(0) | probably_damaging(0.987) | TCGA-BH-A18L-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
MYRIP | SNV | Missense_Mutation | | c.388N>C | p.Lys130Gln | p.K130Q | Q8NFW9 | protein_coding | deleterious(0.02) | probably_damaging(0.958) | TCGA-D8-A1X9-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | adriamycin+cyclophosphamide | SD |
MYRIP | SNV | Missense_Mutation | novel | c.540G>T | p.Arg180Ser | p.R180S | Q8NFW9 | protein_coding | deleterious(0) | probably_damaging(0.932) | TCGA-LL-A5YP-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cytoxan | SD |
MYRIP | insertion | Frame_Shift_Ins | novel | c.1541_1542insACTTCTCTCTCTTTCTCTATGGATTGCAAATGCACACAGAAAAT | p.Glu515LeufsTer52 | p.E515Lfs*52 | Q8NFW9 | protein_coding | | | TCGA-A2-A0EO-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
MYRIP | insertion | Nonsense_Mutation | novel | c.1181_1182insATAAAGAGAAGCCTGAGATCCAGGCCCTGCCTCAGGGAC | p.Gly394_Ser395insTer | p.G394_S395ins* | Q8NFW9 | protein_coding | | | TCGA-AN-A0FX-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
MYRIP | SNV | Missense_Mutation | novel | c.809C>T | p.Thr270Ile | p.T270I | Q8NFW9 | protein_coding | tolerated(0.21) | benign(0.014) | TCGA-2W-A8YY-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |