Tissue | Expression Dynamics | Abbreviation |
Cervix | | CC: Cervix cancer |
HSIL_HPV: HPV-infected high-grade squamous intraepithelial lesions |
N_HPV: HPV-infected normal cervix |
Colorectum (GSE201348) | | FAP: Familial adenomatous polyposis |
CRC: Colorectal cancer |
Colorectum (HTA11) | | AD: Adenomas |
SER: Sessile serrated lesions |
MSI-H: Microsatellite-high colorectal cancer |
MSS: Microsatellite stable colorectal cancer |
Endometrium | | AEH: Atypical endometrial hyperplasia |
EEC: Endometrioid Cancer |
Esophagus | | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias |
LGIN: Low-grade intraepithelial neoplasias |
GC | | CAG: Chronic atrophic gastritis |
CAG with IM: Chronic atrophic gastritis with intestinal metaplasia |
CSG: Chronic superficial gastritis |
GC: Gastric cancer |
SIM: Severe intestinal metaplasia |
WIM: Wild intestinal metaplasia |
Liver | | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
Lung | | AAH: Atypical adenomatous hyperplasia |
AIS: Adenocarcinoma in situ |
IAC: Invasive lung adenocarcinoma |
MIA: Minimally invasive adenocarcinoma |
Oral Cavity | | EOLP: Erosive Oral lichen planus |
LP: leukoplakia |
NEOLP: Non-erosive oral lichen planus |
OSCC: Oral squamous cell carcinoma |
Prostate | | BPH: Benign Prostatic Hyperplasia |
Thyroid | | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis |
PTC: Papillary thyroid cancer |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00182098 | Oral cavity | OSCC | peptidyl-serine modification | 175/7305 | 338/18723 | 1.09e-06 | 1.46e-05 | 175 |
GO:001810510 | Oral cavity | OSCC | peptidyl-serine phosphorylation | 164/7305 | 315/18723 | 1.51e-06 | 1.99e-05 | 164 |
GO:00467779 | Oral cavity | OSCC | protein autophosphorylation | 123/7305 | 227/18723 | 2.31e-06 | 2.93e-05 | 123 |
GO:001003820 | Oral cavity | OSCC | response to metal ion | 188/7305 | 373/18723 | 4.34e-06 | 5.00e-05 | 188 |
GO:003246917 | Oral cavity | OSCC | endoplasmic reticulum calcium ion homeostasis | 19/7305 | 25/18723 | 1.89e-04 | 1.28e-03 | 19 |
GO:00903113 | Oral cavity | OSCC | regulation of protein deacetylation | 30/7305 | 48/18723 | 8.31e-04 | 4.41e-03 | 30 |
GO:007124115 | Oral cavity | OSCC | cellular response to inorganic substance | 111/7305 | 226/18723 | 1.22e-03 | 6.10e-03 | 111 |
GO:00181079 | Oral cavity | OSCC | peptidyl-threonine phosphorylation | 60/7305 | 116/18723 | 3.59e-03 | 1.50e-02 | 60 |
GO:00182109 | Oral cavity | OSCC | peptidyl-threonine modification | 64/7305 | 125/18723 | 3.68e-03 | 1.52e-02 | 64 |
GO:0031063 | Oral cavity | OSCC | regulation of histone deacetylation | 19/7305 | 31/18723 | 9.93e-03 | 3.48e-02 | 19 |
GO:009890115 | Oral cavity | OSCC | regulation of cardiac muscle cell action potential | 17/7305 | 27/18723 | 1.01e-02 | 3.49e-02 | 17 |
GO:007124816 | Oral cavity | OSCC | cellular response to metal ion | 93/7305 | 197/18723 | 1.14e-02 | 3.85e-02 | 93 |
GO:00106447 | Oral cavity | OSCC | cell communication by electrical coupling | 19/7305 | 32/18723 | 1.56e-02 | 5.00e-02 | 19 |
GO:001810514 | Oral cavity | EOLP | peptidyl-serine phosphorylation | 84/2218 | 315/18723 | 3.32e-13 | 1.05e-10 | 84 |
GO:001820914 | Oral cavity | EOLP | peptidyl-serine modification | 87/2218 | 338/18723 | 1.07e-12 | 2.46e-10 | 87 |
GO:003297026 | Oral cavity | EOLP | regulation of actin filament-based process | 93/2218 | 397/18723 | 5.39e-11 | 7.03e-09 | 93 |
GO:001657023 | Oral cavity | EOLP | histone modification | 98/2218 | 463/18723 | 5.58e-09 | 2.96e-07 | 98 |
GO:005123525 | Oral cavity | EOLP | maintenance of location | 75/2218 | 327/18723 | 1.04e-08 | 4.98e-07 | 75 |
GO:005165125 | Oral cavity | EOLP | maintenance of location in cell | 54/2218 | 214/18723 | 4.26e-08 | 1.64e-06 | 54 |
GO:001604924 | Oral cavity | EOLP | cell growth | 97/2218 | 482/18723 | 9.06e-08 | 3.15e-06 | 97 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CAMK2D | SNV | Missense_Mutation | novel | c.709N>A | p.Glu237Lys | p.E237K | | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.998) | TCGA-5L-AAT1-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Hormone Therapy | letrozol | SD |
CAMK2D | SNV | Missense_Mutation | | c.911T>C | p.Ile304Thr | p.I304T | | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.953) | TCGA-AN-A0G0-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CAMK2D | SNV | Missense_Mutation | | c.1514N>A | p.Gly505Glu | p.G505E | | protein_coding | deleterious_low_confidence(0.03) | possibly_damaging(0.597) | TCGA-B6-A0RG-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CAMK2D | insertion | Frame_Shift_Ins | novel | c.70dupG | p.Ala24GlyfsTer30 | p.A24Gfs*30 | | protein_coding | | | TCGA-BH-A18G-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
CAMK2D | deletion | Frame_Shift_Del | novel | c.1417delN | p.Asp473MetfsTer64 | p.D473Mfs*64 | | protein_coding | | | TCGA-EW-A2FV-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | docetaxel | SD |
CAMK2D | SNV | Missense_Mutation | | c.920C>T | p.Thr307Ile | p.T307I | | protein_coding | deleterious_low_confidence(0.01) | possibly_damaging(0.675) | TCGA-AA-3663-01 | Colorectum | colon adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
CAMK2D | SNV | Missense_Mutation | | c.289N>C | p.Glu97Gln | p.E97Q | | protein_coding | deleterious_low_confidence(0.01) | probably_damaging(0.999) | TCGA-AA-A02H-01 | Colorectum | colon adenocarcinoma | Female | >=65 | III/IV | Unknown | Unknown | PD |
CAMK2D | SNV | Missense_Mutation | novel | c.1328C>G | p.Pro443Arg | p.P443R | | protein_coding | deleterious_low_confidence(0.04) | probably_damaging(0.994) | TCGA-AA-A02R-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
CAMK2D | SNV | Missense_Mutation | novel | c.1327C>T | p.Pro443Ser | p.P443S | | protein_coding | tolerated_low_confidence(0.1) | probably_damaging(0.991) | TCGA-AA-A02R-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
CAMK2D | SNV | Missense_Mutation | | c.509N>T | p.Ala170Val | p.A170V | | protein_coding | tolerated_low_confidence(0.08) | probably_damaging(0.999) | TCGA-DM-A1D7-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | GEFITINIB | GEFITINIB | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | GW441756X | GW441756X | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | TAE-684 | TAE-684 | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | SP-600125 | SP-600125 | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | LY-2090314 | LY-2090314 | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | LINIFANIB | LINIFANIB | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | ILORASERTIB | ILORASERTIB | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | SOTRASTAURIN | SOTRASTAURIN | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | | PF-562271 | PF-00562271 | |
817 | CAMK2D | TRANSCRIPTION FACTOR, TRANSPORTER, ENZYME, ION CHANNEL, KINASE, SERINE THREONINE KINASE, DRUGGABLE GENOME | inhibitor | 249565838 | | |