GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:19021151 | Liver | HCC | regulation of organelle assembly | 110/7958 | 186/18723 | 3.30e-06 | 4.34e-05 | 110 |
GO:00440881 | Liver | HCC | regulation of vacuole organization | 33/7958 | 45/18723 | 2.69e-05 | 2.79e-04 | 33 |
GO:003070521 | Liver | HCC | cytoskeleton-dependent intracellular transport | 111/7958 | 195/18723 | 3.25e-05 | 3.28e-04 | 111 |
GO:00109702 | Liver | HCC | transport along microtubule | 90/7958 | 155/18723 | 6.49e-05 | 5.92e-04 | 90 |
GO:20007851 | Liver | HCC | regulation of autophagosome assembly | 28/7958 | 39/18723 | 2.02e-04 | 1.56e-03 | 28 |
GO:006049112 | Liver | HCC | regulation of cell projection assembly | 101/7958 | 188/18723 | 1.20e-03 | 6.69e-03 | 101 |
GO:012003212 | Liver | HCC | regulation of plasma membrane bounded cell projection assembly | 100/7958 | 186/18723 | 1.23e-03 | 6.81e-03 | 100 |
GO:00016553 | Liver | HCC | urogenital system development | 170/7958 | 338/18723 | 2.15e-03 | 1.08e-02 | 170 |
GO:00018222 | Liver | HCC | kidney development | 148/7958 | 293/18723 | 3.25e-03 | 1.49e-02 | 148 |
GO:00720012 | Liver | HCC | renal system development | 152/7958 | 302/18723 | 3.45e-03 | 1.56e-02 | 152 |
GO:0016236110 | Thyroid | PTC | macroautophagy | 167/5968 | 291/18723 | 1.51e-19 | 1.91e-17 | 167 |
GO:0030705111 | Thyroid | PTC | cytoskeleton-dependent intracellular transport | 104/5968 | 195/18723 | 3.87e-10 | 1.24e-08 | 104 |
GO:000703315 | Thyroid | PTC | vacuole organization | 96/5968 | 180/18723 | 1.80e-09 | 5.13e-08 | 96 |
GO:00315037 | Thyroid | PTC | protein-containing complex localization | 107/5968 | 220/18723 | 1.47e-07 | 2.82e-06 | 107 |
GO:00109709 | Thyroid | PTC | transport along microtubule | 80/5968 | 155/18723 | 2.48e-07 | 4.32e-06 | 80 |
GO:0120032111 | Thyroid | PTC | regulation of plasma membrane bounded cell projection assembly | 92/5968 | 186/18723 | 4.12e-07 | 6.83e-06 | 92 |
GO:006049120 | Thyroid | PTC | regulation of cell projection assembly | 92/5968 | 188/18723 | 7.55e-07 | 1.18e-05 | 92 |
GO:000182215 | Thyroid | PTC | kidney development | 133/5968 | 293/18723 | 7.57e-07 | 1.18e-05 | 133 |
GO:000165517 | Thyroid | PTC | urogenital system development | 149/5968 | 338/18723 | 1.41e-06 | 2.01e-05 | 149 |
GO:007200114 | Thyroid | PTC | renal system development | 135/5968 | 302/18723 | 1.76e-06 | 2.43e-05 | 135 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
IFT88 | SNV | Missense_Mutation | | c.767N>T | p.Arg256Ile | p.R256I | Q13099 | protein_coding | tolerated(0.05) | possibly_damaging(0.69) | TCGA-A2-A0CM-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | PD |
IFT88 | SNV | Missense_Mutation | | c.1796N>T | p.Ser599Phe | p.S599F | Q13099 | protein_coding | tolerated(0.27) | benign(0.276) | TCGA-A8-A08L-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
IFT88 | SNV | Missense_Mutation | | c.1020N>C | p.Leu340Phe | p.L340F | Q13099 | protein_coding | deleterious(0) | probably_damaging(0.994) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
IFT88 | SNV | Missense_Mutation | | c.243N>T | p.Lys81Asn | p.K81N | Q13099 | protein_coding | tolerated(0.44) | benign(0.272) | TCGA-C8-A12W-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
IFT88 | SNV | Missense_Mutation | | c.1420G>C | p.Asp474His | p.D474H | Q13099 | protein_coding | deleterious(0) | possibly_damaging(0.498) | TCGA-E2-A14V-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cyclophosphamide | SD |
IFT88 | SNV | Missense_Mutation | | c.1722N>A | p.Met574Ile | p.M574I | Q13099 | protein_coding | tolerated(0.3) | benign(0.06) | TCGA-E2-A1LA-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | arimidex | SD |
IFT88 | insertion | Nonsense_Mutation | novel | c.2376_2377insTAAGAACCTACAGTTAAGAAAAAGTATGCATGC | p.Glu792_Ile793insTer | p.E792_I793ins* | Q13099 | protein_coding | | | TCGA-A8-A08H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
IFT88 | SNV | Missense_Mutation | novel | c.1358A>G | p.Lys453Arg | p.K453R | Q13099 | protein_coding | tolerated(0.17) | probably_damaging(0.98) | TCGA-C5-A7UE-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | SD |
IFT88 | SNV | Missense_Mutation | novel | c.1367N>C | p.Arg456Thr | p.R456T | Q13099 | protein_coding | deleterious(0.05) | benign(0.115) | TCGA-C5-A902-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | SD |
IFT88 | SNV | Missense_Mutation | | c.1366A>G | p.Arg456Gly | p.R456G | Q13099 | protein_coding | deleterious(0.01) | benign(0.079) | TCGA-AA-3715-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |