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Gene: ELAPOR1 |
Gene summary for ELAPOR1 |
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Gene information | Species | Human | Gene symbol | ELAPOR1 | Gene ID | 57535 |
Gene name | endosome-lysosome associated apoptosis and autophagy regulator 1 | |
Gene Alias | EIG121 | |
Cytomap | 1p13.3 | |
Gene Type | protein-coding | GO ID | GO:0000045 | UniProtAcc | Q6UXG2 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
57535 | ELAPOR1 | HTA11_3410_2000001011 | Human | Colorectum | AD | 1.01e-80 | 1.30e+00 | 0.0155 |
57535 | ELAPOR1 | HTA11_2487_2000001011 | Human | Colorectum | SER | 1.83e-24 | 8.57e-01 | -0.1808 |
57535 | ELAPOR1 | HTA11_2951_2000001011 | Human | Colorectum | AD | 5.22e-30 | 1.80e+00 | 0.0216 |
57535 | ELAPOR1 | HTA11_1938_2000001011 | Human | Colorectum | AD | 8.04e-15 | 7.08e-01 | -0.0811 |
57535 | ELAPOR1 | HTA11_78_2000001011 | Human | Colorectum | AD | 4.35e-37 | 1.15e+00 | -0.1088 |
57535 | ELAPOR1 | HTA11_347_2000001011 | Human | Colorectum | AD | 1.34e-48 | 1.38e+00 | -0.1954 |
57535 | ELAPOR1 | HTA11_411_2000001011 | Human | Colorectum | SER | 2.50e-11 | 1.57e+00 | -0.2602 |
57535 | ELAPOR1 | HTA11_2112_2000001011 | Human | Colorectum | SER | 5.26e-10 | 8.18e-01 | -0.2196 |
57535 | ELAPOR1 | HTA11_3361_2000001011 | Human | Colorectum | AD | 3.99e-38 | 1.23e+00 | -0.1207 |
57535 | ELAPOR1 | HTA11_83_2000001011 | Human | Colorectum | SER | 4.95e-16 | 8.86e-01 | -0.1526 |
57535 | ELAPOR1 | HTA11_696_2000001011 | Human | Colorectum | AD | 8.81e-87 | 2.22e+00 | -0.1464 |
57535 | ELAPOR1 | HTA11_866_2000001011 | Human | Colorectum | AD | 1.37e-56 | 1.46e+00 | -0.1001 |
57535 | ELAPOR1 | HTA11_1391_2000001011 | Human | Colorectum | AD | 1.37e-44 | 1.75e+00 | -0.059 |
57535 | ELAPOR1 | HTA11_2992_2000001011 | Human | Colorectum | SER | 1.27e-18 | 1.03e+00 | -0.1706 |
57535 | ELAPOR1 | HTA11_5212_2000001011 | Human | Colorectum | AD | 6.52e-06 | 6.68e-01 | -0.2061 |
57535 | ELAPOR1 | HTA11_5216_2000001011 | Human | Colorectum | SER | 2.21e-18 | 8.56e-01 | -0.1462 |
57535 | ELAPOR1 | HTA11_546_2000001011 | Human | Colorectum | AD | 2.51e-45 | 1.85e+00 | -0.0842 |
57535 | ELAPOR1 | HTA11_9341_2000001011 | Human | Colorectum | SER | 6.89e-14 | 8.27e-01 | -0.00410000000000005 |
57535 | ELAPOR1 | HTA11_7862_2000001011 | Human | Colorectum | AD | 4.78e-35 | 1.37e+00 | -0.0179 |
57535 | ELAPOR1 | HTA11_866_3004761011 | Human | Colorectum | AD | 6.50e-102 | 2.00e+00 | 0.096 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00092671 | Colorectum | SER | cellular response to starvation | 38/2897 | 156/18723 | 2.45e-03 | 2.32e-02 | 38 |
GO:00316681 | Colorectum | SER | cellular response to extracellular stimulus | 54/2897 | 246/18723 | 4.26e-03 | 3.45e-02 | 54 |
GO:00162411 | Colorectum | SER | regulation of macroautophagy | 34/2897 | 141/18723 | 4.74e-03 | 3.72e-02 | 34 |
GO:00316691 | Colorectum | SER | cellular response to nutrient levels | 48/2897 | 215/18723 | 4.82e-03 | 3.78e-02 | 48 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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