GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0031667113 | Thyroid | PTC | response to nutrient levels | 201/5968 | 474/18723 | 7.00e-07 | 1.10e-05 | 201 |
GO:0051100113 | Thyroid | PTC | negative regulation of binding | 81/5968 | 162/18723 | 1.14e-06 | 1.67e-05 | 81 |
GO:000004514 | Thyroid | PTC | autophagosome assembly | 54/5968 | 99/18723 | 2.46e-06 | 3.22e-05 | 54 |
GO:002240615 | Thyroid | PTC | membrane docking | 48/5968 | 86/18723 | 3.72e-06 | 4.73e-05 | 48 |
GO:190503713 | Thyroid | PTC | autophagosome organization | 55/5968 | 103/18723 | 4.75e-06 | 5.79e-05 | 55 |
GO:190211516 | Thyroid | PTC | regulation of organelle assembly | 88/5968 | 186/18723 | 7.41e-06 | 8.65e-05 | 88 |
GO:005105617 | Thyroid | PTC | regulation of small GTPase mediated signal transduction | 132/5968 | 302/18723 | 9.26e-06 | 1.04e-04 | 132 |
GO:007190210 | Thyroid | PTC | positive regulation of protein serine/threonine kinase activity | 93/5968 | 200/18723 | 1.01e-05 | 1.12e-04 | 93 |
GO:000726618 | Thyroid | PTC | Rho protein signal transduction | 68/5968 | 137/18723 | 1.09e-05 | 1.21e-04 | 68 |
GO:004657817 | Thyroid | PTC | regulation of Ras protein signal transduction | 88/5968 | 189/18723 | 1.62e-05 | 1.70e-04 | 88 |
GO:004308718 | Thyroid | PTC | regulation of GTPase activity | 148/5968 | 348/18723 | 1.63e-05 | 1.71e-04 | 148 |
GO:0009636111 | Thyroid | PTC | response to toxic substance | 115/5968 | 262/18723 | 2.70e-05 | 2.63e-04 | 115 |
GO:00162395 | Thyroid | PTC | positive regulation of macroautophagy | 36/5968 | 63/18723 | 2.98e-05 | 2.86e-04 | 36 |
GO:001082210 | Thyroid | PTC | positive regulation of mitochondrion organization | 40/5968 | 74/18723 | 6.30e-05 | 5.53e-04 | 40 |
GO:003209118 | Thyroid | PTC | negative regulation of protein binding | 47/5968 | 94/18723 | 1.90e-04 | 1.42e-03 | 47 |
GO:01400569 | Thyroid | PTC | organelle localization by membrane tethering | 40/5968 | 77/18723 | 1.98e-04 | 1.49e-03 | 40 |
GO:19021176 | Thyroid | PTC | positive regulation of organelle assembly | 35/5968 | 67/18723 | 4.24e-04 | 2.83e-03 | 35 |
GO:00713593 | Thyroid | PTC | cellular response to dsRNA | 15/5968 | 22/18723 | 5.11e-04 | 3.32e-03 | 15 |
GO:00440886 | Thyroid | PTC | regulation of vacuole organization | 25/5968 | 45/18723 | 8.54e-04 | 5.23e-03 | 25 |
GO:00482855 | Thyroid | PTC | organelle fission | 188/5968 | 488/18723 | 9.64e-04 | 5.77e-03 | 188 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ALB | SNV | Missense_Mutation | novel | c.247N>A | p.Ala83Thr | p.A83T | P02768 | protein_coding | tolerated(0.06) | benign(0.068) | TCGA-BH-A0HF-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |
ALB | SNV | Missense_Mutation | novel | c.1814N>T | p.Ala605Val | p.A605V | P02768 | protein_coding | deleterious(0.02) | benign(0.041) | TCGA-BH-A0HF-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |
ALB | SNV | Missense_Mutation | | c.29N>A | p.Leu10His | p.L10H | P02768 | protein_coding | deleterious(0) | possibly_damaging(0.867) | TCGA-D8-A1XQ-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ALB | SNV | Missense_Mutation | | c.1802N>T | p.Ala601Val | p.A601V | P02768 | protein_coding | tolerated(0.53) | benign(0) | TCGA-D8-A1XQ-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ALB | insertion | Nonsense_Mutation | novel | c.75_76insTCTACTTATTGAAAGAGAGAAAGGAAAAAAATATGAAACAG | p.Ala26SerfsTer4 | p.A26Sfs*4 | P02768 | protein_coding | | | TCGA-A2-A0EO-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
ALB | insertion | Nonsense_Mutation | novel | c.806_807insAGCATGGAGTAACTCCATAGGCCAACA | p.Cys269delinsTer | p.C269delins* | P02768 | protein_coding | | | TCGA-BH-A0BM-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
ALB | SNV | Missense_Mutation | | c.1249N>A | p.Glu417Lys | p.E417K | P02768 | protein_coding | deleterious(0.01) | possibly_damaging(0.476) | TCGA-EK-A3GK-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
ALB | SNV | Missense_Mutation | rs267600248 | c.628C>T | p.Arg210Trp | p.R210W | P02768 | protein_coding | deleterious(0.01) | possibly_damaging(0.883) | TCGA-A6-5665-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
ALB | SNV | Missense_Mutation | rs774294755 | c.881N>T | p.Ser294Leu | p.S294L | P02768 | protein_coding | tolerated(0.31) | benign(0.041) | TCGA-AA-A00N-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | PD |
ALB | SNV | Missense_Mutation | rs150388973 | c.946N>A | p.Glu316Lys | p.E316K | P02768 | protein_coding | tolerated(0.07) | benign(0.109) | TCGA-AZ-4313-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Sodium lauryl sulfate | | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Gadofosveset | GADOFOSVESET | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | RALTITREXED | RALTITREXED | 15025739 |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Activated recombinant FVII-albumin fusion protein | | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Oxyphenbutazone | OXYPHENBUTAZONE | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | EPIGALOCATECHIN GALLATE | EPIGALOCATECHIN GALLATE | 20598557 |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | PHENYLBUTAZONE | PHENYLBUTAZONE | 20869876 |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | EPIGALLOCATECHIN | EPIGALLOCATECHIN | 20598557 |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | Iodipamide | IODIPAMIDE | |
213 | ALB | TRANSPORTER, DRUGGABLE GENOME | | [19F]-HALOPERIDOL | [19F]-HALOPERIDOL | |