GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000641719 | Prostate | Tumor | regulation of translation | 161/3246 | 468/18723 | 1.55e-19 | 8.74e-17 | 161 |
GO:009872712 | Prostate | Tumor | maintenance of cell number | 45/3246 | 134/18723 | 3.80e-06 | 6.11e-05 | 45 |
GO:001982712 | Prostate | Tumor | stem cell population maintenance | 44/3246 | 131/18723 | 4.83e-06 | 7.52e-05 | 44 |
GO:000641728 | Skin | AK | regulation of translation | 102/1910 | 468/18723 | 6.79e-14 | 2.36e-11 | 102 |
GO:00198278 | Skin | AK | stem cell population maintenance | 37/1910 | 131/18723 | 5.65e-09 | 4.03e-07 | 37 |
GO:00987279 | Skin | AK | maintenance of cell number | 37/1910 | 134/18723 | 1.10e-08 | 7.11e-07 | 37 |
GO:000641729 | Skin | cSCC | regulation of translation | 226/4864 | 468/18723 | 8.78e-26 | 2.62e-23 | 226 |
GO:001982715 | Skin | cSCC | stem cell population maintenance | 58/4864 | 131/18723 | 4.20e-06 | 6.24e-05 | 58 |
GO:009872715 | Skin | cSCC | maintenance of cell number | 58/4864 | 134/18723 | 9.83e-06 | 1.29e-04 | 58 |
GO:0006417113 | Thyroid | PTC | regulation of translation | 236/5968 | 468/18723 | 2.70e-17 | 2.52e-15 | 236 |
GO:0016055110 | Thyroid | PTC | Wnt signaling pathway | 217/5968 | 444/18723 | 3.71e-14 | 2.30e-12 | 217 |
GO:0198738110 | Thyroid | PTC | cell-cell signaling by wnt | 217/5968 | 446/18723 | 6.68e-14 | 3.73e-12 | 217 |
GO:0030111110 | Thyroid | PTC | regulation of Wnt signaling pathway | 163/5968 | 328/18723 | 1.05e-11 | 4.29e-10 | 163 |
GO:007155919 | Thyroid | PTC | response to transforming growth factor beta | 131/5968 | 256/18723 | 9.20e-11 | 3.17e-09 | 131 |
GO:007156019 | Thyroid | PTC | cellular response to transforming growth factor beta stimulus | 126/5968 | 250/18723 | 7.34e-10 | 2.19e-08 | 126 |
GO:000717919 | Thyroid | PTC | transforming growth factor beta receptor signaling pathway | 104/5968 | 198/18723 | 1.20e-09 | 3.47e-08 | 104 |
GO:0060828110 | Thyroid | PTC | regulation of canonical Wnt signaling pathway | 123/5968 | 253/18723 | 1.83e-08 | 4.26e-07 | 123 |
GO:0048732113 | Thyroid | PTC | gland development | 193/5968 | 436/18723 | 2.88e-08 | 6.42e-07 | 193 |
GO:0060070110 | Thyroid | PTC | canonical Wnt signaling pathway | 141/5968 | 303/18723 | 5.71e-08 | 1.21e-06 | 141 |
GO:001701515 | Thyroid | PTC | regulation of transforming growth factor beta receptor signaling pathway | 69/5968 | 128/18723 | 1.92e-07 | 3.51e-06 | 69 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF7 | SNV | Missense_Mutation | novel | c.1276T>G | p.Cys426Gly | p.C426G | P17097 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-A8-A09M-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Chemotherapy | paclitaxel | CR |
ZNF7 | SNV | Missense_Mutation | rs200609680 | c.693N>C | p.Gln231His | p.Q231H | P17097 | protein_coding | deleterious(0) | benign(0.276) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
ZNF7 | SNV | Missense_Mutation | rs548449450 | c.784N>A | p.Glu262Lys | p.E262K | P17097 | protein_coding | tolerated(0.56) | benign(0.003) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF7 | SNV | Missense_Mutation | novel | c.615N>A | p.Met205Ile | p.M205I | P17097 | protein_coding | tolerated(0.24) | benign(0) | TCGA-LL-A8F5-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cyclophosphamide | SD |
ZNF7 | insertion | Nonsense_Mutation | novel | c.1045_1046insGTTTCTGATTCTGAGGTCTGGTT | p.Glu349GlyfsTer3 | p.E349Gfs*3 | P17097 | protein_coding | | | TCGA-A7-A0CE-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
ZNF7 | insertion | In_Frame_Ins | novel | c.486_487insTCTTGGCAGCTCTTCCAGCCT | p.Asn162_Cys163insSerTrpGlnLeuPheGlnPro | p.N162_C163insSWQLFQP | P17097 | protein_coding | | | TCGA-A8-A06X-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF7 | insertion | Nonsense_Mutation | novel | c.1818_1819insTCACACTGGAGAAAAACCATTTAAATGTGATGAGTGTGGCAAAGG | p.Tyr606_Leu607insSerHisTrpArgLysThrIleTerMetTerTerValTrpGlnArg | p.Y606_L607insSHWRKTI*M**VWQR | P17097 | protein_coding | | | TCGA-A8-A095-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | 5-fluorouracil | CR |
ZNF7 | insertion | Frame_Shift_Ins | novel | c.1111_1112insACAGGACTTTCCTCAGAATCCTGGCTTTGGAGACGTTTCT | p.Arg371AsnfsTer68 | p.R371Nfs*68 | P17097 | protein_coding | | | TCGA-A8-A097-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | tamoxiphen | SD |
ZNF7 | insertion | In_Frame_Ins | novel | c.435_436insAGTGAA | p.Ser145_His146insSerGlu | p.S145_H146insSE | P17097 | protein_coding | | | TCGA-B6-A0RE-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF7 | insertion | Frame_Shift_Ins | novel | c.437_438insAGGTAAAAAGTATGAAACCACT | p.His146GlnfsTer24 | p.H146Qfs*24 | P17097 | protein_coding | | | TCGA-B6-A0RE-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |