GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000640323 | Oral cavity | EOLP | RNA localization | 57/2218 | 201/18723 | 1.62e-10 | 1.68e-08 | 57 |
GO:005116824 | Oral cavity | EOLP | nuclear export | 47/2218 | 154/18723 | 4.45e-10 | 3.76e-08 | 47 |
GO:004682222 | Oral cavity | EOLP | regulation of nucleocytoplasmic transport | 37/2218 | 106/18723 | 4.85e-10 | 4.04e-08 | 37 |
GO:001593121 | Oral cavity | EOLP | nucleobase-containing compound transport | 58/2218 | 222/18723 | 3.44e-09 | 2.10e-07 | 58 |
GO:005065721 | Oral cavity | EOLP | nucleic acid transport | 47/2218 | 163/18723 | 3.53e-09 | 2.12e-07 | 47 |
GO:005065821 | Oral cavity | EOLP | RNA transport | 47/2218 | 163/18723 | 3.53e-09 | 2.12e-07 | 47 |
GO:001657023 | Oral cavity | EOLP | histone modification | 98/2218 | 463/18723 | 5.58e-09 | 2.96e-07 | 98 |
GO:005123622 | Oral cavity | EOLP | establishment of RNA localization | 47/2218 | 166/18723 | 6.73e-09 | 3.48e-07 | 47 |
GO:002241121 | Oral cavity | EOLP | cellular component disassembly | 94/2218 | 443/18723 | 1.00e-08 | 4.89e-07 | 94 |
GO:005102821 | Oral cavity | EOLP | mRNA transport | 38/2218 | 130/18723 | 7.28e-08 | 2.61e-06 | 38 |
GO:00510811 | Oral cavity | EOLP | nuclear envelope disassembly | 8/2218 | 11/18723 | 4.54e-06 | 9.41e-05 | 8 |
GO:003105622 | Oral cavity | EOLP | regulation of histone modification | 38/2218 | 152/18723 | 5.18e-06 | 1.05e-04 | 38 |
GO:00303971 | Oral cavity | EOLP | membrane disassembly | 8/2218 | 12/18723 | 1.22e-05 | 2.09e-04 | 8 |
GO:004683121 | Oral cavity | EOLP | regulation of RNA export from nucleus | 8/2218 | 12/18723 | 1.22e-05 | 2.09e-04 | 8 |
GO:000640521 | Oral cavity | EOLP | RNA export from nucleus | 24/2218 | 84/18723 | 2.70e-05 | 3.95e-04 | 24 |
GO:00322391 | Oral cavity | EOLP | regulation of nucleobase-containing compound transport | 8/2218 | 15/18723 | 1.14e-04 | 1.27e-03 | 8 |
GO:007142621 | Oral cavity | EOLP | ribonucleoprotein complex export from nucleus | 21/2218 | 76/18723 | 1.42e-04 | 1.53e-03 | 21 |
GO:007116621 | Oral cavity | EOLP | ribonucleoprotein complex localization | 21/2218 | 77/18723 | 1.74e-04 | 1.80e-03 | 21 |
GO:000640621 | Oral cavity | EOLP | mRNA export from nucleus | 17/2218 | 59/18723 | 3.48e-04 | 3.20e-03 | 17 |
GO:007142721 | Oral cavity | EOLP | mRNA-containing ribonucleoprotein complex export from nucleus | 17/2218 | 59/18723 | 3.48e-04 | 3.20e-03 | 17 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
AKAP8 | SNV | Missense_Mutation | rs764482753 | c.1192N>T | p.Arg398Cys | p.R398C | O43823 | protein_coding | deleterious(0) | probably_damaging(0.98) | TCGA-A8-A09Z-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
AKAP8 | SNV | Missense_Mutation | novel | c.1489C>T | p.Arg497Trp | p.R497W | O43823 | protein_coding | deleterious(0) | probably_damaging(0.995) | TCGA-AC-A2BK-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Chemotherapy | cytoxan | CR |
AKAP8 | SNV | Missense_Mutation | rs767177827 | c.1268C>G | p.Thr423Ser | p.T423S | O43823 | protein_coding | deleterious(0.01) | probably_damaging(0.998) | TCGA-AN-A04D-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
AKAP8 | SNV | Missense_Mutation | | c.1600A>C | p.Lys534Gln | p.K534Q | O43823 | protein_coding | deleterious(0.02) | probably_damaging(0.939) | TCGA-E2-A1L7-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | cyclophosphamide | PD |
AKAP8 | SNV | Missense_Mutation | novel | c.1997N>C | p.Arg666Thr | p.R666T | O43823 | protein_coding | tolerated_low_confidence(0.6) | benign(0.005) | TCGA-DR-A0ZM-01 | Cervix | cervical & endocervical cancer | Female | <65 | III/IV | Unspecific | Cisplatin | SD |
AKAP8 | SNV | Missense_Mutation | | c.1581N>C | p.Leu527Phe | p.L527F | O43823 | protein_coding | deleterious(0) | probably_damaging(0.964) | TCGA-EK-A2RA-01 | Cervix | cervical & endocervical cancer | Female | >=65 | I/II | Unknown | Unknown | SD |
AKAP8 | SNV | Missense_Mutation | | c.374C>T | p.Ser125Phe | p.S125F | O43823 | protein_coding | deleterious(0.05) | benign(0.072) | TCGA-EK-A3GN-01 | Cervix | cervical & endocervical cancer | Female | <65 | III/IV | Unknown | Unknown | SD |
AKAP8 | SNV | Missense_Mutation | novel | c.1015T>G | p.Ser339Ala | p.S339A | O43823 | protein_coding | tolerated(0.09) | possibly_damaging(0.565) | TCGA-5M-AAT6-01 | Colorectum | colon adenocarcinoma | Female | <65 | III/IV | Unknown | Unknown | PD |
AKAP8 | SNV | Missense_Mutation | | c.712N>T | p.Pro238Ser | p.P238S | O43823 | protein_coding | tolerated(0.08) | benign(0.062) | TCGA-AA-3492-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
AKAP8 | SNV | Missense_Mutation | | c.2006N>T | p.Pro669Leu | p.P669L | O43823 | protein_coding | tolerated_low_confidence(0.3) | benign(0) | TCGA-AA-3710-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |