GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000974325 | Oral cavity | NEOLP | response to carbohydrate | 45/2005 | 253/18723 | 4.43e-04 | 4.00e-03 | 45 |
GO:00311092 | Oral cavity | NEOLP | microtubule polymerization or depolymerization | 26/2005 | 122/18723 | 4.52e-04 | 4.06e-03 | 26 |
GO:003428425 | Oral cavity | NEOLP | response to monosaccharide | 41/2005 | 225/18723 | 4.69e-04 | 4.20e-03 | 41 |
GO:005149417 | Oral cavity | NEOLP | negative regulation of cytoskeleton organization | 32/2005 | 163/18723 | 5.07e-04 | 4.48e-03 | 32 |
GO:005068631 | Oral cavity | NEOLP | negative regulation of mRNA processing | 10/2005 | 29/18723 | 5.71e-04 | 4.96e-03 | 10 |
GO:001063932 | Oral cavity | NEOLP | negative regulation of organelle organization | 57/2005 | 348/18723 | 7.37e-04 | 6.03e-03 | 57 |
GO:000974624 | Oral cavity | NEOLP | response to hexose | 39/2005 | 219/18723 | 1.00e-03 | 7.68e-03 | 39 |
GO:007132223 | Oral cavity | NEOLP | cellular response to carbohydrate stimulus | 31/2005 | 163/18723 | 1.07e-03 | 8.08e-03 | 31 |
GO:005105113 | Oral cavity | NEOLP | negative regulation of transport | 72/2005 | 470/18723 | 1.14e-03 | 8.49e-03 | 72 |
GO:007267331 | Oral cavity | NEOLP | lamellipodium morphogenesis | 7/2005 | 17/18723 | 1.18e-03 | 8.72e-03 | 7 |
GO:190274522 | Oral cavity | NEOLP | positive regulation of lamellipodium organization | 11/2005 | 37/18723 | 1.26e-03 | 9.21e-03 | 11 |
GO:007133323 | Oral cavity | NEOLP | cellular response to glucose stimulus | 29/2005 | 151/18723 | 1.30e-03 | 9.44e-03 | 29 |
GO:000167824 | Oral cavity | NEOLP | cellular glucose homeostasis | 32/2005 | 172/18723 | 1.31e-03 | 9.48e-03 | 32 |
GO:007133123 | Oral cavity | NEOLP | cellular response to hexose stimulus | 29/2005 | 153/18723 | 1.60e-03 | 1.12e-02 | 29 |
GO:004511621 | Oral cavity | NEOLP | protein neddylation | 7/2005 | 18/18723 | 1.75e-03 | 1.21e-02 | 7 |
GO:007132623 | Oral cavity | NEOLP | cellular response to monosaccharide stimulus | 29/2005 | 154/18723 | 1.78e-03 | 1.22e-02 | 29 |
GO:000703022 | Oral cavity | NEOLP | Golgi organization | 29/2005 | 157/18723 | 2.40e-03 | 1.53e-02 | 29 |
GO:00310572 | Oral cavity | NEOLP | negative regulation of histone modification | 12/2005 | 46/18723 | 2.66e-03 | 1.66e-02 | 12 |
GO:19019833 | Oral cavity | NEOLP | regulation of protein acetylation | 17/2005 | 77/18723 | 2.80e-03 | 1.73e-02 | 17 |
GO:00070203 | Oral cavity | NEOLP | microtubule nucleation | 10/2005 | 35/18723 | 2.88e-03 | 1.77e-02 | 10 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
F7 | SNV | Missense_Mutation | novel | c.308N>A | p.Ser103Tyr | p.S103Y | P08709 | protein_coding | tolerated(0.17) | benign(0.028) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
F7 | SNV | Missense_Mutation | | c.729N>G | p.Ile243Met | p.I243M | P08709 | protein_coding | deleterious(0.04) | benign(0.157) | TCGA-AN-A0AM-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
F7 | SNV | Missense_Mutation | novel | c.1132N>A | p.Gly378Arg | p.G378R | P08709 | protein_coding | tolerated(0.22) | benign(0) | TCGA-AR-A2LJ-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | adriamycin | SD |
F7 | SNV | Missense_Mutation | rs749760143 | c.973N>A | p.Glu325Lys | p.E325K | P08709 | protein_coding | tolerated(0.05) | probably_damaging(0.933) | TCGA-C8-A1HM-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | doxorubicin | CR |
F7 | insertion | Frame_Shift_Ins | novel | c.731_732insGGGAAAATGGGCAGGTCAGC | p.Asn244LysfsTer28 | p.N244Kfs*28 | P08709 | protein_coding | | | TCGA-AN-A0AM-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
F7 | insertion | Frame_Shift_Ins | novel | c.757_758insGCAA | p.His253ArgfsTer29 | p.H253Rfs*29 | P08709 | protein_coding | | | TCGA-BH-A0HY-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | taxotere | CR |
F7 | insertion | In_Frame_Ins | novel | c.759_760insCCCAAGGCCGAATTGTGGGGGGCAAGG | p.His253_Cys254insProLysAlaGluLeuTrpGlyAlaArg | p.H253_C254insPKAELWGAR | P08709 | protein_coding | | | TCGA-BH-A0HY-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | taxotere | CR |
F7 | SNV | Missense_Mutation | | c.475N>C | p.Glu159Gln | p.E159Q | P08709 | protein_coding | deleterious(0.04) | benign(0.115) | TCGA-DR-A0ZM-01 | Cervix | cervical & endocervical cancer | Female | <65 | III/IV | Unspecific | Cisplatin | SD |
F7 | SNV | Missense_Mutation | novel | c.348N>C | p.Gln116His | p.Q116H | P08709 | protein_coding | deleterious(0.02) | probably_damaging(0.961) | TCGA-EA-A3HU-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
F7 | SNV | Missense_Mutation | | c.160N>A | p.Val54Ile | p.V54I | P08709 | protein_coding | tolerated(0.2) | benign(0.01) | TCGA-AA-3811-01 | Colorectum | colon adenocarcinoma | Female | >=65 | III/IV | Unknown | Unknown | PD |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | | Vatreptacog alfa (activated) | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | | Factor viia | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | | Recombinant factor VIIa PEGylated liposomal | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | | F-7TG | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | | BAX-817 | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | inhibitor | 178103166 | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | | CB-813 | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | | Activated recombinant FVII-albumin fusion protein | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | inhibitor | 252166701 | | |
2155 | F7 | ENZYME, DRUGGABLE GENOME, PROTEASE | | Eptacog alfa intravenous | | |