GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00609982 | Liver | NAFLD | regulation of dendritic spine development | 13/1882 | 61/18723 | 6.77e-03 | 4.79e-02 | 13 |
GO:000218112 | Liver | Cirrhotic | cytoplasmic translation | 120/4634 | 148/18723 | 2.95e-47 | 1.85e-43 | 120 |
GO:000989612 | Liver | Cirrhotic | positive regulation of catabolic process | 215/4634 | 492/18723 | 1.13e-20 | 3.56e-18 | 215 |
GO:190136111 | Liver | Cirrhotic | organic cyclic compound catabolic process | 213/4634 | 495/18723 | 1.58e-19 | 3.67e-17 | 213 |
GO:003133112 | Liver | Cirrhotic | positive regulation of cellular catabolic process | 190/4634 | 427/18723 | 1.94e-19 | 4.18e-17 | 190 |
GO:001943911 | Liver | Cirrhotic | aromatic compound catabolic process | 202/4634 | 467/18723 | 6.93e-19 | 1.28e-16 | 202 |
GO:190331111 | Liver | Cirrhotic | regulation of mRNA metabolic process | 140/4634 | 288/18723 | 1.07e-18 | 1.91e-16 | 140 |
GO:004427011 | Liver | Cirrhotic | cellular nitrogen compound catabolic process | 195/4634 | 451/18723 | 2.99e-18 | 4.94e-16 | 195 |
GO:004670011 | Liver | Cirrhotic | heterocycle catabolic process | 192/4634 | 445/18723 | 7.17e-18 | 1.12e-15 | 192 |
GO:005068411 | Liver | Cirrhotic | regulation of mRNA processing | 81/4634 | 137/18723 | 1.05e-17 | 1.60e-15 | 81 |
GO:000641712 | Liver | Cirrhotic | regulation of translation | 194/4634 | 468/18723 | 7.28e-16 | 8.79e-14 | 194 |
GO:003465511 | Liver | Cirrhotic | nucleobase-containing compound catabolic process | 171/4634 | 407/18723 | 9.07e-15 | 9.33e-13 | 171 |
GO:000640111 | Liver | Cirrhotic | RNA catabolic process | 126/4634 | 278/18723 | 4.64e-14 | 4.10e-12 | 126 |
GO:000640211 | Liver | Cirrhotic | mRNA catabolic process | 109/4634 | 232/18723 | 1.30e-13 | 1.09e-11 | 109 |
GO:00457277 | Liver | Cirrhotic | positive regulation of translation | 71/4634 | 136/18723 | 4.99e-12 | 3.52e-10 | 71 |
GO:003425012 | Liver | Cirrhotic | positive regulation of cellular amide metabolic process | 78/4634 | 162/18723 | 8.62e-11 | 4.66e-09 | 78 |
GO:000095611 | Liver | Cirrhotic | nuclear-transcribed mRNA catabolic process | 58/4634 | 112/18723 | 6.55e-10 | 3.06e-08 | 58 |
GO:190331311 | Liver | Cirrhotic | positive regulation of mRNA metabolic process | 56/4634 | 118/18723 | 7.05e-08 | 2.14e-06 | 56 |
GO:004348811 | Liver | Cirrhotic | regulation of mRNA stability | 69/4634 | 158/18723 | 1.44e-07 | 3.87e-06 | 69 |
GO:004348711 | Liver | Cirrhotic | regulation of RNA stability | 73/4634 | 170/18723 | 1.44e-07 | 3.87e-06 | 73 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CPEB3 | SNV | Missense_Mutation | | c.1096N>C | p.Gly366Arg | p.G366R | Q8NE35 | protein_coding | deleterious(0.02) | benign(0.261) | TCGA-AN-A0AR-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CPEB3 | SNV | Missense_Mutation | | c.19N>C | p.Met7Leu | p.M7L | Q8NE35 | protein_coding | tolerated_low_confidence(0.24) | benign(0.354) | TCGA-B6-A0IH-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
CPEB3 | insertion | Frame_Shift_Ins | rs763864563 | c.188_189insC | p.Ala64GlyfsTer258 | p.A64Gfs*258 | Q8NE35 | protein_coding | | | TCGA-AR-A5QN-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Chemotherapy | taxotere | SD |
CPEB3 | insertion | Frame_Shift_Ins | novel | c.258_259insGCAAGTGTGTGGCAAGGTGCCGGCATAGTCCCAGGATG | p.Pro87AlafsTer46 | p.P87Afs*46 | Q8NE35 | protein_coding | | | TCGA-B6-A0IB-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | PD |
CPEB3 | SNV | Missense_Mutation | rs764406144 | c.1653C>G | p.Ile551Met | p.I551M | Q8NE35 | protein_coding | deleterious(0) | probably_damaging(0.973) | TCGA-C5-A7CK-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | SD |
CPEB3 | SNV | Missense_Mutation | | c.1280C>T | p.Pro427Leu | p.P427L | Q8NE35 | protein_coding | deleterious(0) | possibly_damaging(0.621) | TCGA-EA-A50E-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | PD |
CPEB3 | SNV | Missense_Mutation | novel | c.645N>G | p.Ile215Met | p.I215M | Q8NE35 | protein_coding | tolerated(0.35) | benign(0.276) | TCGA-VS-A958-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
CPEB3 | SNV | Missense_Mutation | novel | c.1544N>G | p.Val515Gly | p.V515G | Q8NE35 | protein_coding | deleterious(0) | possibly_damaging(0.897) | TCGA-A6-6141-01 | Colorectum | colon adenocarcinoma | Male | <65 | I/II | Chemotherapy | 5-fu | SD |
CPEB3 | SNV | Missense_Mutation | | c.1712N>A | p.Arg571His | p.R571H | Q8NE35 | protein_coding | deleterious(0.03) | benign(0.263) | TCGA-A6-6653-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
CPEB3 | SNV | Missense_Mutation | novel | c.1682G>A | p.Arg561Gln | p.R561Q | Q8NE35 | protein_coding | deleterious(0.01) | possibly_damaging(0.831) | TCGA-AA-3672-01 | Colorectum | colon adenocarcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |