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Gene: VWA9 |
Gene summary for VWA9 |
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Gene information | Species | Human | Gene symbol | VWA9 | Gene ID | 81556 |
Gene name | integrator complex subunit 14 | |
Gene Alias | C15orf44 | |
Cytomap | 15q22.31 | |
Gene Type | protein-coding | GO ID | GO:0006139 | UniProtAcc | Q96SY0 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
81556 | VWA9 | P1T-E | Human | Esophagus | ESCC | 4.18e-02 | 2.33e-01 | 0.0875 |
81556 | VWA9 | P2T-E | Human | Esophagus | ESCC | 7.71e-29 | 5.41e-01 | 0.1177 |
81556 | VWA9 | P4T-E | Human | Esophagus | ESCC | 1.89e-23 | 5.75e-01 | 0.1323 |
81556 | VWA9 | P5T-E | Human | Esophagus | ESCC | 2.48e-13 | 1.96e-01 | 0.1327 |
81556 | VWA9 | P8T-E | Human | Esophagus | ESCC | 1.25e-21 | 3.38e-01 | 0.0889 |
81556 | VWA9 | P9T-E | Human | Esophagus | ESCC | 9.11e-09 | 2.23e-01 | 0.1131 |
81556 | VWA9 | P10T-E | Human | Esophagus | ESCC | 1.07e-23 | 3.30e-01 | 0.116 |
81556 | VWA9 | P11T-E | Human | Esophagus | ESCC | 4.38e-10 | 3.05e-01 | 0.1426 |
81556 | VWA9 | P12T-E | Human | Esophagus | ESCC | 7.79e-22 | 3.82e-01 | 0.1122 |
81556 | VWA9 | P15T-E | Human | Esophagus | ESCC | 2.90e-17 | 4.11e-01 | 0.1149 |
81556 | VWA9 | P16T-E | Human | Esophagus | ESCC | 6.26e-27 | 6.26e-01 | 0.1153 |
81556 | VWA9 | P20T-E | Human | Esophagus | ESCC | 4.33e-17 | 2.44e-01 | 0.1124 |
81556 | VWA9 | P21T-E | Human | Esophagus | ESCC | 8.67e-12 | 1.86e-01 | 0.1617 |
81556 | VWA9 | P22T-E | Human | Esophagus | ESCC | 2.27e-16 | 2.85e-01 | 0.1236 |
81556 | VWA9 | P23T-E | Human | Esophagus | ESCC | 8.58e-21 | 4.23e-01 | 0.108 |
81556 | VWA9 | P24T-E | Human | Esophagus | ESCC | 3.01e-09 | 2.69e-01 | 0.1287 |
81556 | VWA9 | P26T-E | Human | Esophagus | ESCC | 1.34e-24 | 4.00e-01 | 0.1276 |
81556 | VWA9 | P27T-E | Human | Esophagus | ESCC | 4.69e-17 | 2.49e-01 | 0.1055 |
81556 | VWA9 | P28T-E | Human | Esophagus | ESCC | 2.07e-16 | 2.02e-01 | 0.1149 |
81556 | VWA9 | P30T-E | Human | Esophagus | ESCC | 3.56e-19 | 6.39e-01 | 0.137 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Thyroid | PTC | ![]() |
Thyroid | goiters | ![]() |
Thyroid | ATC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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