GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:004578516 | Endometrium | AEH | positive regulation of cell adhesion | 96/2100 | 437/18723 | 5.50e-11 | 7.18e-09 | 96 |
GO:002240714 | Endometrium | AEH | regulation of cell-cell adhesion | 79/2100 | 448/18723 | 2.90e-05 | 5.40e-04 | 79 |
GO:002240910 | Endometrium | AEH | positive regulation of cell-cell adhesion | 54/2100 | 284/18723 | 6.94e-05 | 1.07e-03 | 54 |
GO:19030398 | Endometrium | AEH | positive regulation of leukocyte cell-cell adhesion | 46/2100 | 239/18723 | 1.72e-04 | 2.24e-03 | 46 |
GO:00421109 | Endometrium | AEH | T cell activation | 81/2100 | 487/18723 | 1.78e-04 | 2.30e-03 | 81 |
GO:00508709 | Endometrium | AEH | positive regulation of T cell activation | 41/2100 | 216/18723 | 5.08e-04 | 5.18e-03 | 41 |
GO:00071599 | Endometrium | AEH | leukocyte cell-cell adhesion | 63/2100 | 371/18723 | 5.11e-04 | 5.21e-03 | 63 |
GO:00508639 | Endometrium | AEH | regulation of T cell activation | 57/2100 | 329/18723 | 5.58e-04 | 5.59e-03 | 57 |
GO:00027645 | Endometrium | AEH | immune response-regulating signaling pathway | 76/2100 | 468/18723 | 5.76e-04 | 5.71e-03 | 76 |
GO:19030379 | Endometrium | AEH | regulation of leukocyte cell-cell adhesion | 57/2100 | 336/18723 | 9.42e-04 | 8.57e-03 | 57 |
GO:00508525 | Endometrium | AEH | T cell receptor signaling pathway | 26/2100 | 123/18723 | 1.03e-03 | 9.15e-03 | 26 |
GO:00026838 | Endometrium | AEH | negative regulation of immune system process | 69/2100 | 434/18723 | 1.76e-03 | 1.41e-02 | 69 |
GO:00420989 | Endometrium | AEH | T cell proliferation | 35/2100 | 199/18723 | 4.66e-03 | 2.98e-02 | 35 |
GO:00421298 | Endometrium | AEH | regulation of T cell proliferation | 31/2100 | 171/18723 | 4.73e-03 | 3.00e-02 | 31 |
GO:00018198 | Endometrium | AEH | positive regulation of cytokine production | 71/2100 | 467/18723 | 4.76e-03 | 3.02e-02 | 71 |
GO:00071627 | Endometrium | AEH | negative regulation of cell adhesion | 49/2100 | 303/18723 | 5.43e-03 | 3.37e-02 | 49 |
GO:00706638 | Endometrium | AEH | regulation of leukocyte proliferation | 41/2100 | 245/18723 | 5.77e-03 | 3.52e-02 | 41 |
GO:004578517 | Endometrium | EEC | positive regulation of cell adhesion | 98/2168 | 437/18723 | 6.15e-11 | 8.38e-09 | 98 |
GO:002240715 | Endometrium | EEC | regulation of cell-cell adhesion | 84/2168 | 448/18723 | 4.98e-06 | 1.24e-04 | 84 |
GO:002240914 | Endometrium | EEC | positive regulation of cell-cell adhesion | 56/2168 | 284/18723 | 4.36e-05 | 7.15e-04 | 56 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
TCN1 | SNV | Missense_Mutation | rs766356612 | c.275N>T | p.Ser92Leu | p.S92L | P20061 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-A2-A0EQ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
TCN1 | SNV | Missense_Mutation | novel | c.473N>C | p.Asn158Thr | p.N158T | P20061 | protein_coding | tolerated(0.14) | benign(0.098) | TCGA-A8-A08H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
TCN1 | SNV | Missense_Mutation | rs778765850 | c.451G>A | p.Val151Ile | p.V151I | P20061 | protein_coding | tolerated(0.18) | possibly_damaging(0.724) | TCGA-AN-A049-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
TCN1 | SNV | Missense_Mutation | | c.681N>C | p.Lys227Asn | p.K227N | P20061 | protein_coding | deleterious(0.04) | probably_damaging(0.979) | TCGA-B6-A0I8-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
TCN1 | SNV | Missense_Mutation | | c.681N>C | p.Lys227Asn | p.K227N | P20061 | protein_coding | deleterious(0.04) | probably_damaging(0.979) | TCGA-E9-A22B-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | tamoxiphen | SD |
TCN1 | SNV | Missense_Mutation | rs371448135 | c.1139N>A | p.Arg380His | p.R380H | P20061 | protein_coding | deleterious(0) | benign(0.039) | TCGA-C5-A7CK-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | SD |
TCN1 | SNV | Missense_Mutation | novel | c.1187N>T | p.Asn396Ile | p.N396I | P20061 | protein_coding | deleterious(0) | possibly_damaging(0.606) | TCGA-C5-A8YR-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | PD |
TCN1 | SNV | Missense_Mutation | | c.691N>C | p.Glu231Gln | p.E231Q | P20061 | protein_coding | tolerated(0.19) | benign(0.053) | TCGA-JW-A852-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | PD |
TCN1 | SNV | Missense_Mutation | novel | c.843C>G | p.Phe281Leu | p.F281L | P20061 | protein_coding | deleterious(0.03) | benign(0.376) | TCGA-VS-A8Q8-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | PD |
TCN1 | SNV | Missense_Mutation | | c.413N>A | p.Gly138Asp | p.G138D | P20061 | protein_coding | tolerated(0.14) | benign(0.031) | TCGA-AA-3663-01 | Colorectum | colon adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |