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Gene: MIR29B2CHG |
Gene summary for MIR29B2CHG |
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Gene information | Species | Human | Gene symbol | MIR29B2CHG | Gene ID | 100128537 |
Gene name | MIR29B2 and MIR29C host gene | |
Gene Alias | C1orf132 | |
Cytomap | 1q32.2 | |
Gene Type | ncRNA | GO ID | GO:0008150 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100128537 | MIR29B2CHG | HTA12-26-1 | Human | Pancreas | PDAC | 1.19e-18 | 7.92e-01 | 0.3728 |
100128537 | MIR29B2CHG | HTA12-29-1 | Human | Pancreas | PDAC | 2.60e-33 | 7.36e-01 | 0.3722 |
100128537 | MIR29B2CHG | PTC01 | Human | Thyroid | PTC | 1.50e-26 | 5.15e-01 | 0.1899 |
100128537 | MIR29B2CHG | PTC03 | Human | Thyroid | PTC | 1.38e-20 | 6.97e-01 | 0.1784 |
100128537 | MIR29B2CHG | PTC04 | Human | Thyroid | PTC | 2.83e-29 | 4.97e-01 | 0.1927 |
100128537 | MIR29B2CHG | PTC05 | Human | Thyroid | PTC | 4.28e-31 | 9.00e-01 | 0.2065 |
100128537 | MIR29B2CHG | PTC06 | Human | Thyroid | PTC | 6.91e-41 | 9.59e-01 | 0.2057 |
100128537 | MIR29B2CHG | PTC07 | Human | Thyroid | PTC | 1.21e-24 | 4.63e-01 | 0.2044 |
100128537 | MIR29B2CHG | ATC1 | Human | Thyroid | ATC | 4.70e-02 | 1.39e-01 | 0.2878 |
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Tissue | Expression Dynamics | Abbreviation |
Thyroid | ![]() | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis | ||
PTC: Papillary thyroid cancer |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Thyroid | PTC | ![]() |
Thyroid | goiters | ![]() |
Thyroid | ATC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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