GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0002064112 | Thyroid | PTC | epithelial cell development | 101/5968 | 220/18723 | 8.53e-06 | 9.74e-05 | 101 |
GO:000188519 | Thyroid | PTC | endothelial cell development | 37/5968 | 64/18723 | 1.62e-05 | 1.70e-04 | 37 |
GO:00301986 | Thyroid | PTC | extracellular matrix organization | 124/5968 | 301/18723 | 3.75e-04 | 2.53e-03 | 124 |
GO:00430626 | Thyroid | PTC | extracellular structure organization | 124/5968 | 302/18723 | 4.38e-04 | 2.92e-03 | 124 |
GO:0003158111 | Thyroid | PTC | endothelium development | 62/5968 | 136/18723 | 5.45e-04 | 3.48e-03 | 62 |
GO:004544619 | Thyroid | PTC | endothelial cell differentiation | 55/5968 | 118/18723 | 5.64e-04 | 3.59e-03 | 55 |
GO:00452296 | Thyroid | PTC | external encapsulating structure organization | 124/5968 | 304/18723 | 5.96e-04 | 3.79e-03 | 124 |
GO:003019812 | Thyroid | ATC | extracellular matrix organization | 152/6293 | 301/18723 | 8.63e-10 | 2.24e-08 | 152 |
GO:004306212 | Thyroid | ATC | extracellular structure organization | 152/6293 | 302/18723 | 1.17e-09 | 2.94e-08 | 152 |
GO:004522912 | Thyroid | ATC | external encapsulating structure organization | 152/6293 | 304/18723 | 2.11e-09 | 5.08e-08 | 152 |
GO:000206428 | Thyroid | ATC | epithelial cell development | 103/6293 | 220/18723 | 3.06e-05 | 2.55e-04 | 103 |
GO:000188526 | Thyroid | ATC | endothelial cell development | 36/6293 | 64/18723 | 1.62e-04 | 1.11e-03 | 36 |
GO:000315825 | Thyroid | ATC | endothelium development | 66/6293 | 136/18723 | 2.16e-04 | 1.42e-03 | 66 |
GO:004544623 | Thyroid | ATC | endothelial cell differentiation | 56/6293 | 118/18723 | 1.23e-03 | 6.44e-03 | 56 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
COL15A1 | SNV | Missense_Mutation | | c.2638A>G | p.Lys880Glu | p.K880E | P39059 | protein_coding | tolerated(0.81) | benign(0.001) | TCGA-A8-A09Z-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | | c.907N>C | p.Glu303Gln | p.E303Q | P39059 | protein_coding | deleterious(0.04) | benign(0.03) | TCGA-AN-A0XN-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | | c.1147N>T | p.Gly383Trp | p.G383W | P39059 | protein_coding | deleterious_low_confidence(0.03) | possibly_damaging(0.759) | TCGA-BH-A0B4-01 | Breast | breast invasive carcinoma | Male | >=65 | III/IV | Hormone Therapy | tamoxiphen | SD |
COL15A1 | SNV | Missense_Mutation | novel | c.2302N>C | p.Glu768Gln | p.E768Q | P39059 | protein_coding | deleterious(0.03) | probably_damaging(0.991) | TCGA-BH-A0B6-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | | c.3400N>A | p.Leu1134Met | p.L1134M | P39059 | protein_coding | tolerated(0.09) | probably_damaging(0.997) | TCGA-BH-A204-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
COL15A1 | SNV | Missense_Mutation | | c.1515N>A | p.Asp505Glu | p.D505E | P39059 | protein_coding | tolerated_low_confidence(0.09) | benign(0.001) | TCGA-C8-A12Q-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Unknown | Unknown | PD |
COL15A1 | insertion | In_Frame_Ins | novel | c.2300_2301insCATTCAAATGAGTGCATCAGCTTATCTCCAGGTGAACTGTCAATT | p.Gly767_Glu768insIleGlnMetSerAlaSerAlaTyrLeuGlnValAsnCysGlnLeu | p.G767_E768insIQMSASAYLQVNCQL | P39059 | protein_coding | | | TCGA-A2-A0EY-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
COL15A1 | insertion | Nonsense_Mutation | novel | c.564_565insGGTGAGTATTAAATCATGTTCTATGAAACTTCTGTTTCAGTGTTA | p.Gln188_Arg189insGlyGluTyrTerIleMetPheTyrGluThrSerValSerValLeu | p.Q188_R189insGEY*IMFYETSVSVL | P39059 | protein_coding | | | TCGA-A8-A07O-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | | CR |
COL15A1 | insertion | Nonsense_Mutation | novel | c.592_593insAATGTATG | p.Ser198Ter | p.S198* | P39059 | protein_coding | | | TCGA-A8-A0A1-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | tamoxiphen | SD |
COL15A1 | insertion | Frame_Shift_Ins | novel | c.593_594insAGAGCGCTTAGAGCAGGGCCTGGTGCAGA | p.Ser199GlufsTer67 | p.S199Efs*67 | P39059 | protein_coding | | | TCGA-A8-A0A1-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | tamoxiphen | SD |