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Gene: C7orf73 |
Gene summary for C7ORF73 |
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Gene information | Species | Human | Gene symbol | C7orf73 | Gene ID | 647087 |
Gene name | short transmembrane mitochondrial protein 1 | |
Gene Alias | C7orf73 | |
Cytomap | 7q33 | |
Gene Type | protein-coding | GO ID | GO:0001816 | UniProtAcc | E0CX11 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
647087 | C7orf73 | HTA11_99999970781_79442 | Human | Colorectum | MSS | 4.93e-21 | 3.83e-01 | 0.294 |
647087 | C7orf73 | HTA11_99999965104_69814 | Human | Colorectum | MSS | 8.49e-18 | 5.98e-01 | 0.281 |
647087 | C7orf73 | HTA11_99999971662_82457 | Human | Colorectum | MSS | 9.10e-25 | 5.32e-01 | 0.3859 |
647087 | C7orf73 | HTA11_99999973899_84307 | Human | Colorectum | MSS | 1.86e-10 | 3.35e-01 | 0.2585 |
647087 | C7orf73 | HTA11_99999974143_84620 | Human | Colorectum | MSS | 4.93e-21 | 3.75e-01 | 0.3005 |
647087 | C7orf73 | AEH-subject1 | Human | Endometrium | AEH | 1.12e-54 | -6.46e-01 | -0.3059 |
647087 | C7orf73 | AEH-subject2 | Human | Endometrium | AEH | 3.14e-48 | -6.46e-01 | -0.2525 |
647087 | C7orf73 | AEH-subject3 | Human | Endometrium | AEH | 3.66e-55 | -6.46e-01 | -0.2576 |
647087 | C7orf73 | AEH-subject4 | Human | Endometrium | AEH | 4.88e-38 | -6.46e-01 | -0.2657 |
647087 | C7orf73 | AEH-subject5 | Human | Endometrium | AEH | 3.66e-55 | -6.46e-01 | -0.2953 |
647087 | C7orf73 | EEC-subject1 | Human | Endometrium | EEC | 6.20e-50 | -6.46e-01 | -0.2682 |
647087 | C7orf73 | EEC-subject2 | Human | Endometrium | EEC | 2.45e-51 | -6.46e-01 | -0.2607 |
647087 | C7orf73 | EEC-subject3 | Human | Endometrium | EEC | 8.27e-52 | -6.46e-01 | -0.2525 |
647087 | C7orf73 | EEC-subject4 | Human | Endometrium | EEC | 1.03e-53 | -6.46e-01 | -0.2571 |
647087 | C7orf73 | EEC-subject5 | Human | Endometrium | EEC | 1.25e-56 | -6.46e-01 | -0.249 |
647087 | C7orf73 | GSM5276934 | Human | Endometrium | EEC | 1.03e-53 | -6.46e-01 | -0.0913 |
647087 | C7orf73 | GSM5276935 | Human | Endometrium | EEC | 3.10e-53 | -6.46e-01 | -0.123 |
647087 | C7orf73 | GSM5276937 | Human | Endometrium | EEC | 1.47e-45 | -6.46e-01 | -0.0897 |
647087 | C7orf73 | GSM6177620_NYU_UCEC1_lib1_lib1 | Human | Endometrium | EEC | 4.85e-40 | -6.46e-01 | -0.1869 |
647087 | C7orf73 | GSM6177620_NYU_UCEC1_lib2_lib2 | Human | Endometrium | EEC | 5.68e-36 | -6.46e-01 | -0.1875 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Thyroid | PTC | ![]() |
Thyroid | goiters | ![]() |
Thyroid | ATC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
C7orf73 | SNV | Missense_Mutation | novel | c.60G>T | p.Gln20His | p.Q20H | E0CX11 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.977) | TCGA-F5-6814-01 | Colorectum | rectum adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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