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Gene: ADAMTSL4-AS1 |
Gene summary for ADAMTSL4-AS1 |
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Gene information | Species | Human | Gene symbol | ADAMTSL4-AS1 | Gene ID | 574406 |
Gene name | ADAMTSL4 antisense RNA 1 | |
Gene Alias | C1orf138 | |
Cytomap | 1q21.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
574406 | ADAMTSL4-AS1 | CCI_1 | Human | Cervix | CC | 1.63e-11 | 9.79e-01 | 0.528 |
574406 | ADAMTSL4-AS1 | CCI_2 | Human | Cervix | CC | 1.69e-09 | 6.50e-01 | 0.5249 |
574406 | ADAMTSL4-AS1 | CCI_3 | Human | Cervix | CC | 1.10e-11 | 4.92e-01 | 0.516 |
574406 | ADAMTSL4-AS1 | HTA11_3410_2000001011 | Human | Colorectum | AD | 1.08e-08 | 1.93e-01 | 0.0155 |
574406 | ADAMTSL4-AS1 | HTA11_2487_2000001011 | Human | Colorectum | SER | 2.14e-15 | 5.13e-01 | -0.1808 |
574406 | ADAMTSL4-AS1 | HTA11_1938_2000001011 | Human | Colorectum | AD | 4.00e-03 | 1.74e-01 | -0.0811 |
574406 | ADAMTSL4-AS1 | HTA11_78_2000001011 | Human | Colorectum | AD | 6.11e-04 | 1.68e-01 | -0.1088 |
574406 | ADAMTSL4-AS1 | HTA11_347_2000001011 | Human | Colorectum | AD | 1.27e-13 | 3.44e-01 | -0.1954 |
574406 | ADAMTSL4-AS1 | HTA11_411_2000001011 | Human | Colorectum | SER | 2.50e-11 | 6.31e-01 | -0.2602 |
574406 | ADAMTSL4-AS1 | HTA11_2112_2000001011 | Human | Colorectum | SER | 1.88e-13 | 9.42e-01 | -0.2196 |
574406 | ADAMTSL4-AS1 | HTA11_3361_2000001011 | Human | Colorectum | AD | 3.86e-11 | 3.70e-01 | -0.1207 |
574406 | ADAMTSL4-AS1 | HTA11_83_2000001011 | Human | Colorectum | SER | 2.92e-07 | 2.84e-01 | -0.1526 |
574406 | ADAMTSL4-AS1 | HTA11_696_2000001011 | Human | Colorectum | AD | 4.78e-17 | 3.95e-01 | -0.1464 |
574406 | ADAMTSL4-AS1 | HTA11_866_2000001011 | Human | Colorectum | AD | 2.07e-08 | 2.48e-01 | -0.1001 |
574406 | ADAMTSL4-AS1 | HTA11_1391_2000001011 | Human | Colorectum | AD | 5.65e-19 | 4.68e-01 | -0.059 |
574406 | ADAMTSL4-AS1 | HTA11_5212_2000001011 | Human | Colorectum | AD | 1.91e-11 | 5.15e-01 | -0.2061 |
574406 | ADAMTSL4-AS1 | HTA11_546_2000001011 | Human | Colorectum | AD | 2.42e-10 | 4.02e-01 | -0.0842 |
574406 | ADAMTSL4-AS1 | HTA11_866_3004761011 | Human | Colorectum | AD | 2.47e-04 | 1.30e-01 | 0.096 |
574406 | ADAMTSL4-AS1 | HTA11_10711_2000001011 | Human | Colorectum | AD | 3.52e-05 | 1.83e-01 | 0.0338 |
574406 | ADAMTSL4-AS1 | HTA11_7696_3000711011 | Human | Colorectum | AD | 3.52e-13 | 2.38e-01 | 0.0674 |
Page: 1 2 3 4 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Thyroid | PTC | ![]() |
Thyroid | goiters | ![]() |
Thyroid | ATC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |