GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000170111 | Liver | HCC | in utero embryonic development | 204/7958 | 367/18723 | 2.44e-07 | 4.30e-06 | 204 |
GO:000189211 | Liver | HCC | embryonic placenta development | 50/7958 | 82/18723 | 5.62e-04 | 3.61e-03 | 50 |
GO:000189011 | Liver | HCC | placenta development | 81/7958 | 144/18723 | 5.91e-04 | 3.75e-03 | 81 |
GO:00606694 | Liver | HCC | embryonic placenta morphogenesis | 19/7958 | 26/18723 | 1.57e-03 | 8.23e-03 | 19 |
GO:006145811 | Liver | HCC | reproductive system development | 205/7958 | 427/18723 | 1.16e-02 | 4.27e-02 | 205 |
GO:0001701111 | Thyroid | PTC | in utero embryonic development | 175/5968 | 367/18723 | 1.40e-10 | 4.73e-09 | 175 |
GO:000189224 | Thyroid | PTC | embryonic placenta development | 44/5968 | 82/18723 | 3.51e-05 | 3.30e-04 | 44 |
GO:0061458112 | Thyroid | PTC | reproductive system development | 173/5968 | 427/18723 | 8.70e-05 | 7.23e-04 | 173 |
GO:0048608111 | Thyroid | PTC | reproductive structure development | 170/5968 | 424/18723 | 1.86e-04 | 1.41e-03 | 170 |
GO:0001890112 | Thyroid | PTC | placenta development | 66/5968 | 144/18723 | 3.06e-04 | 2.14e-03 | 66 |
GO:006066917 | Thyroid | PTC | embryonic placenta morphogenesis | 16/5968 | 26/18723 | 1.75e-03 | 9.51e-03 | 16 |
GO:000170126 | Thyroid | ATC | in utero embryonic development | 183/6293 | 367/18723 | 6.62e-11 | 2.11e-09 | 183 |
GO:006145827 | Thyroid | ATC | reproductive system development | 193/6293 | 427/18723 | 3.32e-07 | 4.92e-06 | 193 |
GO:004860825 | Thyroid | ATC | reproductive structure development | 190/6293 | 424/18723 | 8.40e-07 | 1.11e-05 | 190 |
GO:000189026 | Thyroid | ATC | placenta development | 70/6293 | 144/18723 | 1.33e-04 | 9.33e-04 | 70 |
GO:0001892111 | Thyroid | ATC | embryonic placenta development | 42/6293 | 82/18723 | 7.34e-04 | 4.11e-03 | 42 |
GO:00485688 | Thyroid | ATC | embryonic organ development | 172/6293 | 427/18723 | 2.08e-03 | 9.84e-03 | 172 |
GO:006066918 | Thyroid | ATC | embryonic placenta morphogenesis | 15/6293 | 26/18723 | 9.95e-03 | 3.63e-02 | 15 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF568 | SNV | Missense_Mutation | novel | c.205N>G | p.Gln69Glu | p.Q69E | Q3ZCX4 | protein_coding | deleterious(0) | probably_damaging(0.991) | TCGA-3C-AALI-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unspecific | Poly E | Complete Response |
ZNF568 | SNV | Missense_Mutation | | c.1458G>A | p.Met486Ile | p.M486I | Q3ZCX4 | protein_coding | tolerated(0.48) | benign(0.269) | TCGA-BH-A0DO-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF568 | SNV | Missense_Mutation | | c.170N>A | p.Leu57His | p.L57H | Q3ZCX4 | protein_coding | deleterious(0) | possibly_damaging(0.771) | TCGA-D8-A1XW-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin+cyclophosphamide | SD |
ZNF568 | deletion | Frame_Shift_Del | novel | c.73delN | p.Ala26LeufsTer23 | p.A26Lfs*23 | Q3ZCX4 | protein_coding | | | TCGA-D8-A27V-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
ZNF568 | SNV | Missense_Mutation | novel | c.1091N>A | p.Cys364Tyr | p.C364Y | Q3ZCX4 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-C5-A1M7-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF568 | SNV | Missense_Mutation | novel | c.583N>C | p.Glu195Gln | p.E195Q | Q3ZCX4 | protein_coding | tolerated(1) | benign(0.001) | TCGA-C5-A7X8-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | SD |
ZNF568 | SNV | Missense_Mutation | | c.1409N>T | p.Gly470Val | p.G470V | Q3ZCX4 | protein_coding | deleterious(0) | probably_damaging(0.984) | TCGA-EK-A2IP-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF568 | SNV | Missense_Mutation | | c.38N>G | p.Val13Gly | p.V13G | Q3ZCX4 | protein_coding | deleterious_low_confidence(0.03) | benign(0) | TCGA-FU-A40J-01 | Cervix | cervical & endocervical cancer | Female | <65 | III/IV | Chemotherapy | carboplatin | CR |
ZNF568 | SNV | Missense_Mutation | | c.1124C>T | p.Ser375Leu | p.S375L | Q3ZCX4 | protein_coding | deleterious(0.01) | benign(0.354) | TCGA-JW-A5VL-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF568 | SNV | Missense_Mutation | novel | c.157N>A | p.Val53Met | p.V53M | | protein_coding | tolerated(0.05) | benign(0.142) | TCGA-VS-A8QH-01 | Cervix | cervical & endocervical cancer | Female | >=65 | I/II | Chemotherapy | gemcitabine | PD |